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INTRODUCTION ACMEZID M TABLET is a combination of Gliclazide and Metformin, which belongs to the group of medicines called Antidiabetic agents. It is used in the management of diabetes mellitus when dietary measures, physical exercise, and weight loss alone are not sufficient to control blood...
ACMEZID M TABLET is a combination of Gliclazide and Metformin, which belongs to the group of medicines called Antidiabetic agents. It is used in the management of diabetes mellitus when dietary measures, physical exercise, and weight loss alone are not sufficient to control blood glucose.
ACMEZID M TABLET is not recommended for use if you have chronic obstructive pulmonary disease, kidney disease, or liver failure. Consult your doctor before taking it.
ACMEZID M TABLET is not recommended for use during pregnancy or in breastfeeding women. ACMEZID M TABLET is not recommended for use in children as safety and effectiveness have not been established. Consult your doctor before taking it.
The most common side effects of taking ACMEZID M TABLET are nausea, diarrhea, gastric pain, constipation, vomiting, metallic taste in the mouth, rash, pruritus, urticaria, erythema, and flushing. Consult your doctor if any of the side effects worsen.
ACMEZID M TABLET effectively controls blood glucose levels, where Gliclazide works by increasing the amount of insulin by stimulating the pancreas and helps control blood glucose levels. Metformin works by decreasing the production of glucose in the liver, decreasing the intestinal absorption of glucose, increasing insulin sensitivity, and allowing better glucose uptake and utilization by the body.
Take ACMEZID M TABLET, preferably just before meals, during meals, or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.
Include fiber-rich foods in your diet, such as fresh fruits, vegetables, and whole-grain cereals, and drink plenty of fluids. Exercise more regularly and stay active. Contact your doctor if constipation persists.
Drink lots of fluids, such as water or fruit juices, to keep yourself hydrated. Do not take any medicine on your own to treat diarrhea. Contact your doctor if your diarrhea does not improve.
Take ACMEZID M TABLET with a meal. Stick to simple meals. Avoid eating oily or spicy food. Contact your doctor if your nausea and vomiting do not improve.
Avoid hot baths because hot water can irritate your skin further. Do not scratch the affected area. Use sunscreen and wear protective clothing while going outside. Use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if your rashes worsen.
Rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heating pad on your stomach. Do not self-treat on your own, consult your doctor if the symptom does not improve on its own.
ACMEZID M TABLET is not recommended for use during pregnancy. Consult your doctor before taking it.
ACMEZID M TABLET is not recommended for use by breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.
Do not drive or operate any machinery if you have increased sweating, a fast heartbeat, vision disorders or difficulty in concentration, dizziness, weakness, or blurred vision after taking ACMEZID M TABLET.
Avoid consumption of alcohol while taking ACMEZID M TABLET, as it may increase the risk of unwanted side effects.
ACMEZID M TABLET is not recommended for use if you have kidney disease. Consult your doctor before taking it.
ACMEZID M TABLET is not recommended for use if you have liver failure. Consult your doctor before taking it.
Do not take ACMEZID M TABLET if you are allergic to Gliclazide, Metformin, or any of the other ingredients of this medicine.
ACMEZID M TABLET is not recommended for use if you have chronic obstructive pulmonary disease. Consult your doctor before taking it.
ACMEZID M TABLET is not recommended for use if you have coronary heart disease, cardiac failure, or peripheral vascular disease. Consult your doctor before taking it.
ACMEZID M TABLET is not recommended for use in children as safety and effectiveness have not been established. Consult your doctor before taking it.
ACMEZID M TABLET should be used with caution only in elderly patients with normal kidney function. Consult your doctor before taking it.
ACMEZID M TABLET is not recommended for use if you:
A. Drug-Drug interactions:
Before taking ACMEZID M TABLET, inform your doctor if you are taking any of the following medicines, such as:
Overdosage:
If you or anyone else accidentally took more ACMEZID M TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage may cause low blood sugar (hypoglycemia), and symptoms include dizziness, lightheadedness, hunger, nervousness, shaky feelings, drowsiness, confusion, perspiration, and palpitations. Severe hypoglycemic reactions include fits, neurological disorders, and lactic acidosis.
| Drug | : | Gliclazide, Metformin |
| Pharmacological Category | : | Sulfonylureas, Biguanides |
| Therapeutic Indication | : | Type II diabetes mellitus |
| Dosage Forms | : | Tablet |
Q: What if I forget to take ACMEZID M TABLET?
A: If you miss a dose of ACMEZID M TABLET, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Q: How does ACMEZID M TABLET work?
A: ACMEZID M TABLET effectively controls blood glucose levels, where Gliclazide works by increasing the amount of insulin by stimulating the pancreas and helping control blood glucose levels. Metformin works by decreasing the production of glucose in the liver, decreasing the intestinal absorption of glucose, increasing insulin sensitivity, and allowing better glucose uptake and utilization by the body.
Q: What are the side effects of taking ACMEZID M TABLET?
A: The most common side effects of taking ACMEZID M TABLET are nausea, diarrhea, gastric pain, constipation, vomiting, metallic taste in the mouth, rash, pruritus, urticaria, erythema, and flushing. Consult your doctor if any of the side effects worsen.
Q: Is ACMEZID M TABLET safe in pregnancy?
A: ACMEZID M TABLET is not recommended for use during pregnancy. Inform your doctor if you are pregnant or planning to have a baby before taking this medicine.
Q: Who should not take ACMEZID M TABLET?
A: ACMEZID M TABLET is not recommended for use if you have chronic obstructive pulmonary disease, kidney disease, and liver failure, type-1 diabetes mellitus, or have severe ketosis and acidosis, diabetic precoma and coma, severe trauma, or severe infections. Consult your doctor before taking it.
1. KD. Tripathi. Insulin, Oral Antidiabetic Drugs and Glucagon. Essentials of medical pharmacology. Eight edition. 2019. Page –295.
2. Corcoran C, Jacobs TF. Metformin. NIH National Library of Medicine, National center for biotechnology information. Statpearls. January 2023. [Accessed on 18th January 2024]. https://www.ncbi.nlm.nih.gov/books/NBK518983/
3. Panacea Biotec Limited. Gliclazide and metformin. [Revised in September 2014] [Accessed on 18th January 2024]. https://media.panaceabiotec.com/documents/2019/7/27/ProductMonograph-GlizidM-GliclazideplusMetformin.pdf
4. Brown & Burk UK Ltd. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 18th January 2024]. https://www.medicines.org.uk/emc/files/pil.10760.pdf
5. Drug bank. Gliclazide. [Accessed on 18th January 2024]. https://go.drugbank.com/drugs/DB01120
6. Drug bank. Metformin. [Accessed on 18th January 2024]. https://go.drugbank.com/drugs/DB00331
Written By Dr. N. Sai Swaroop, Pharm.D
Last updated on 23 Jan 2024 | 11:58 AM(IST)