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INTRODUCTION ASSURANS TABLET contains Sildenafil which belongs to the group of medicines called Phosphodiesterase type 5 (PDE 5) inhibitors. It is used for pulmonary arterial hypertension (PAH) in adults and children. Pulmonary arterial hypertension can be defined as an increased blood pressur...
ASSURANS TABLET contains Sildenafil which belongs to the group of medicines called Phosphodiesterase type 5 (PDE 5) inhibitors. It is used for pulmonary arterial hypertension (PAH) in adults and children. Pulmonary arterial hypertension can be defined as an increased blood pressure in the blood vessels that supplies the lungs. It can be caused due to narrowing of blood vessels (arteries) supplying the heart and the lungs. Symptoms of PAH might include shortness of breath, tiredness, weakness and feeling faint.
Before taking ASSURANS TABLET inform your doctor if you have any liver, kidney, or heart problems. It should be used with caution in patients with eye problems, stomach problems, anemia or penile deformity. Avoid consuming grapefruit juice while taking ASSURANS TABLET, as it may increase the risk of side effects.ASSURANS TABLET should be used in pregnant or breastfeeding women only if it is considered necessary by the physician.
Women of childbearing potential should use suitable contraceptive method to avoid pregnancy while undergoing therapy with ASSURANS TABLET. The most common side effects of ASSURANS TABLET are headache, muscle pain or stiffness, dizziness, blurred vision, or flushing. Consult your doctor if any of the side effect troubles you.
ASSURANS TABLET reduces blood pressure within the lungs, where sildenafil acts by blocking the effects of certain enzymes (PDE5) which limits blood flow to the lungs. As a result, it causes widening of blood vessels (arteries) supplying the lungs, improves blood supply to the lungs and enhances pulmonary function.
Take ASSURANS TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking ASSURANS TABLET without consulting your doctor.
Stop taking ASSURANS TABLET and contact your doctor immediately if you experience any of the following side effects:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Take ASSURANS TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.
ASSURANS TABLET is generally not recommended for use in pregnant unless considered necessary by the physician. Therefore, consult your doctor before taking it. Women of child-bearing potential should use proper contraceptive method to avoid pregnancy while undergoing therapy with ASSURANS TABLET.
ASSURANS TABLET should be used with caution for use in breastfeeding women. Therefore, consult your doctor before taking it.
Do not drive or operate any machines if you experience dizziness or blurred vision after taking ASSURANS TABLET.
Avoid consumption of alcohol while taking ASSURANS TABLET as it may reduce the effectiveness of ASSURANS TABLET.
ASSURANS TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
ASSURANS TABLET is not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other minor liver problems. Therefore, consult your doctor before taking it.
Do not take ASSURANS TABLET if you are allergic to Sildenafil.
ASSURANS TABLET should be used with caution in patients with pulmonary hypertension caused due to narrowing or blockade of veins (instead of arteries). Consult your doctor before taking.
ASSURANS TABLET is not recommended for use in patients with severe heart diseases (such as any recent heart attack or stroke, or severe low blood pressure). It should be used with caution in patients with other heart problems (such as problems in heart chambers or valves, low blood pressure at rest). Consult your doctor before taking it.
ASSURANS TABLET should be used in children and adolescents (aged between 1-18 years) only if prescribed by the physician. It is not recommended for use in infants aged below 1 year. Therefore, consult your doctor before taking.
ASSURANS TABLET should be used with caution in elderly patients. Consult your doctor before taking.
ASSURANS TABLET is not recommended for use if you:
Before taking ASSURANS TABLET inform your doctor if you have:
A. Drug-Drug interactions:
Before taking ASSURANS TABLET, inform your doctor if you are taking any of the following medicines such as:
B. Drug-Food Interactions:
Avoid drinking grapefruit juice while taking ASSURANS TABLET, as it may increase the risk of side effects.
Overdosage:
If you or anyone else accidentally took more ASSURANS TABLET, consult your doctor immediately as there can be chances of increased side effects.
| Drug | : | Sildenafil |
| Pharmacological Category | : | Phosphodiesterase type 5 inhibitors |
| Therapeutic Indication | : | Pulmonary Arterial Hypertension |
| Dosage Forms | : | Tablet, Capsule, Oral Disintegrating Strips, Oral Jelly, Injection, Effervescent Tablet, Spray |
Q: What are the uses of ASSURANS TABLET?
A: ASSURANS TABLET is used for pulmonary arterial hypertension (PAH) in both adults and in children. It reduces blood pressure within the lungs by relaxing the blood vessels supplying the lungs.
Q: What does ASSURANS TABLET do?
A: ASSURANS TABLET reduces blood pressure within the lungs, where sildenafil acts by blocking the effects of certain enzymes (PDE5) which limits blood flow to the lungs. As a result, it causes widening of blood vessels (arteries) supplying the lungs, improves blood supply to the lungs and enhances pulmonary functions.
Q: How to take ASSURANS TABLET?
A: ASSURANS TABLET should be taken as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: Can elderly men take ASSURANS TABLET?
A: Yes. ASSURANS TABLET should be used with caution in elderly patients, especially if they have any pre-existing heart conditions and taking medicines for it. Consult your doctor before taking.
Q: Can ASSURANS TABLET be used in women?
A: Yes. ASSURANS TABLET can be used in women for pulmonary arterial hypertension. However, it should be used in pregnant or breastfeeding women only if considered necessary by the physician. Therefore, consult your doctor before taking it. Women of child-bearing potential should use proper contraceptive method to avoid pregnancy while undergoing therapy with ASSURANS TABLET.
Q: What are the side effects of ASSURANS TABLET?
A: The most common side effects of ASSURANS TABLET are headache, muscle pain or stiffness, dizziness, blurred vision, or flushing. Consult your doctor if any of the side effect troubles you.
Q: What medicines should I avoid while taking ASSURANS TABLET?
A: Before taking ASSURANS TABLET inform your doctor about all the medicines that you use for current illness. Avoid concomittant use of similar medicines which can relaxes your blood pressure such as nitrates (Ex. nitroglycerin). It is also important to inform your doctor about the use of antibiotics (Ex. erythromycin, clarithromycin, telithromycin, rifampicin), antivirals (Ex. saquinavir and ritonavir) and antiepileptic drugs (Ex. carbamazepine, phenytoin).
Q: Can I consume alcohol while taking ASSURANS TABLET?
A: No. Consumption of alcohol while taking ASSURANS TABLET gives less efficient results. Avoid alcohol to achieve maximum benefits of ASSURANS TABLET.
1. K.D. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page – 303-304.
2. Sukhdeep Bhogal, Ola Khraisha, Mohammad Al Madani, Jennifer Treece, Steven Baumrucker and Timir K Paul. Sildenafil for Pulmonary Arterial Hypertension. NIH National Library of Medicine, National center for biotechnology information. July/Aug 2019. [Accessed on 27th November, 2023] https://pubmed.ncbi.nlm.nih.gov/30946047/
3. Gautam V Ramani and Myung H Park. Update on the clinical utility of sildenafil in the treatment of pulmonary arterial hypertension. NIH. National Library of Medicine. National Centre of Biotechnology Information. PMC. PubMed Central. May 2010. [Accessed on 27th November, 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880338/
4. Pfizer Ltd. Electronic Medicines Compendium (EMC). [Revised 1/2021] [Accessed on 27th November, 2023] https://www.medicines.org.uk/emc/files/pil.181.pdf
Written By Dr. Janet.C, Pharm.D
Last updated on 29 Nov 2023 | 11:27 AM(IST)