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INTRODUCTION RENDEF 6 TABLET contains Deflazacort which belongs to the group of medicines called Anti-Inflammatory and Immunomodulator Drugs. It is used to treat inflammation in asthma (inflamed airways), arthritis (pain and inflammation in the joints) and allergies. RENDE...
RENDEF 6 TABLET contains Deflazacort which belongs to the group of medicines called Anti-Inflammatory and Immunomodulator Drugs. It is used to treat inflammation in asthma (inflamed airways), arthritis (pain and inflammation in the joints) and allergies.
RENDEF 6 TABLET is also used in treatment of problems with your skin, kidney, heart, digestive system, eyes or blood and where your body has growths (tumours). It also used to prevent rejection after organ transplant operations.
RENDEF 6 TABLET is not recommended for use in patients who have any untreated systemic infection and had any vaccinations with live viruses.
Before taking RENDEF 6 TABLET, inform your doctor if you have epilepsy, problems in liver, kidney or heart, diabetes, high blood pressure, mental health problems, osteoporosis, glaucoma, oesophagitis, ulcerative colitis, diverticulitis or peptic ulcer and pheochromocytoma.
RENDEF 6 TABLET is generally not recommended for use in pregnant and breastfeeding women unless clearly advised by the doctor. RENDEF 6 TABLET should be used with caution in children and elderly patients due to increased risk of side effects.
The most common side effects of taking RENDEF 6 TABLET are excessive facial hair, increased weight, skin redness, rash, nausea and abdominal pain. Consult your doctor if any of the side effects worsen.
RENDEF 6 TABLET works by preventing the release of certain chemicals involved in the immune and allergic reactions, that result in inflammation. This type of action can reduce inflammation in a particular area, control various diseases characterised by excessive inflammation and treats autoimmune disease conditions where immune system attacks the body tissues. It also supresses white blood cells along with immune system to prevent the body from attacking foreign tissue in organ transplantation.
Take RENDEF 6 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Stop taking RENDEF 6 TABLET and contact your doctor immediately if you experience any of the following side effects:
Take fiber rich foods in your diet such as fresh fruits, vegetables and whole grain cereals and drink plenty of fluids. Exercise more regularly (such as daily walk) and stay active. Consult your doctor if the symptom gets worse.
Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.
Try to rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, consult your doctor.
RENDEF 6 TABLET is generally not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking RENDEF 6 TABLET.
RENDEF 6 TABLET should be used with caution in breastfeeding women unless considered clearly necessary. Consult your doctor before taking RENDEF 6 TABLET.
Do not drive or operate any machines if you feel dizzy or feel like everything around you is spinning or feel disorientated (vertigo) after taking RENDEF 6 TABLET.
RENDEF 6 TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking RENDEF 6 TABLET.
RENDEF 6 TABLET should be used with caution in patients with liver problems. Consult your doctor before taking RENDEF 6 TABLET.
Do not take RENDEF 6 TABLET if you are allergic to Deflazacort. It should be used with caution in patients who have ever had a bad reaction such as muscle weakness to any steroids.
RENDEF 6 TABLET should be used with caution in patients who had or have tuberculosis. Consult your doctor before taking RENDEF 6 TABLET.
RENDEF 6 TABLET should be used with caution in patients with high blood pressure or heart problems. Consult your doctor before taking RENDEF 6 TABLET.
RENDEF 6 TABLET should be used with caution in children. Your child’s doctor may adjust the dose based on child’s age and body and dose may be initiated with the lowest effective dose. Consult your child’s doctor for advice.
RENDEF 6 TABLET should be used with caution in elderly patients due to increased risk of side effects. Consult your doctor before taking RENDEF 6 TABLET.
RENDEF 6 TABLET is not recommended for use if you:
Before taking RENDEF 6 TABLET, inform your doctor if you:
A. Drug-Drug interactions:
Before taking RENDEF 6 TABLET, inform your doctor if you are taking any of the following medicines:
Overdosage:
If you or anyone else accidentally takes too much of RENDEF 6 TABLET, consult your doctor immediately or visit the nearby hospital.
| Drug | : | Deflazacort |
| Pharmacological Category | : | Glucocorticoids |
| Therapeutic Indication | : | Autoimmune diseases, Prevent rejection of organ transplantation and tumours |
| Dosage Forms | : | Tablet, Oral suspension, Suspension, Syrup |
Q. What is RENDEF 6 TABLET used for?
A. RENDEF 6 TABLET is used to treat inflammation including asthma, arthritis, allergies and problems in skin, heart, kidney, eyes, digestive system or blood. It is also used in certain type of cancer treatment and to suppress the immune system after transplant operations to prevent organ rejection.
Q. Does RENDEF 6 TABLET increase blood sugar?
A. Yes, you might experience increased thirst and needing to pass water more often than usual which could be signs of diabetes. If you are already diabetic, your doctor may prescribe more of your diabetes medicine to balance the effects of RENDEF 6 TABLET. Always consult your doctor for advice before taking RENDEF 6 TABLET.
Q. What are the side effects of RENDEF 6 TABLET?
A. RENDEF 6 TABLET can cause common side effects such as excessive facial hair, increased weight, puffy face appearance, skin redness, abdominal pain, constipation, irritability, abnormal behaviour, fever, back pain, bruise, nausea and nosebleeds. If any of these side effects get worsen, consult your doctor immediately.
Q. Can I stop taking RENDEF 6 TABLET suddenly?
A. No, you should not stop taking RENDEF 6 TABLET without consulting your doctor because it may cause problems such as high temperature, runny nose, red eyes, aching muscles and joints, itchy skin, and weight loss along with vomiting, headache and drowsiness. This is more likely to happen in children. If you had to stop the treatment with RENDEF 6 TABLET, the dose will be gradually reduced.
Q. Can I take vaccine while taking RENDEF 6 TABLET?
A. If you are going to have any injections or vaccinations, tell the doctor that you are taking RENDEF 6 TABLET. This includes those needed for a foreign holiday. Some vaccines should not be given to patients taking this medicine. This is because RENDEF 6 TABLET can affect the way some vaccines work.
1. KD. Tripathi. Steroids, Corticosteroids. Essentials of medical pharmacology. Fourth edition. 2013. Chapter 19. Page – 284 to 297.
2. Anthony Markham & Harriet M. Bryson. Deflazacort - A Review of its Pharmacological Properties and Therapeutic Efficacy. October 2012 [Accessed on 15th June 2022] https://link.springer.com/article/10.2165/00003495-199550020-00008
3. Laura C. McAdam, Amanda L. Mayo, Benjamin A. Alman, and W. Douglas Biggar. The Canadian experience with long term deflazacort treatment in Duchenne muscular dystrophy. [Revised in May 2012] [Accessed on 15th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440807/
4. Sanofi S.r.l. Electronic Medicines Compendium (EMC). [Revised in August 2022] [Accessed on 15th June 2022] https://www.medicines.org.uk/emc/files/pil.6287.pdf
5. Marathon Pharmaceuticals. U.S. Food & Drug Administration. [Revised in February 2017] [Accessed on 15th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/208684s000,208685s000lbl.pdf
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 17 Feb 2023 | 06:20 PM(IST)