INTRODUCTION

M THYRONI 100MCG TABLET contains Thyroxine , which belongs to the group of medicines called Synthetic thyroid hormones. It is used in the management of hypothyroidism.

M THYRONI 100MCG TABLET is not recommended for use if you have untreated hyperthyroidism, untreated subclinical or overt thyrotoxicosis, untreated adrenal insufficiency, or pituitary insufficiency. Consult your doctor before taking it.

M THYRONI 100MCG TABLET should be used with caution in patients with coronary heart disease such as acute myocardial infarction, acute myocarditis, acute pancarditis, angina pectoris, and hypertension. Consult your doctor before taking it.

M THYRONI 100MCG TABLET can be used safely in pregnant and breastfeeding women and requires dose adjustment. Consult your doctor before taking it.

The most common side effects of taking M THYRONI 100MCG TABLET are increased appetite, weight variations, headache, vomiting, diarrhea, changes in the menstrual cycle, fever, sensitivity to heat, cramps, and mood swings. Consult your doctor if any of the side effects worsen.

USES OF M THYRONI 100MCG TABLET

• To manage hypothyroidism

HOW M THYRONI 100MCG TABLET WORKS

M THYRONI 100MCG TABLET contains thyroxine, which controls the entire metabolic activity of the body and is very important for the proper functioning of our body.

DIRECTIONS FOR USE

Take M THYRONI 100MCG TABLET in the morning on an empty stomach at least half an hour before breakfast or as directed by the physician. Swallow the medicine with a glass of water. Do not chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.

SIDE EFFECTS OF M THYRONI 100MCG TABLET

HOW TO MANAGE SIDE EFFECTS

Diarrhea

Drink lots of fluids, such as water or fruit juices, to keep yourself hydrated. Do not take any medicine on your own to treat diarrhea. Contact your doctor if your diarrhea does not improve.

Headache

Rest and relax. Drink plenty of fluids, such as water or ORS (Oral Rehydrating Solution), and apply a pain-relieving balm to the head if necessary. Contact your doctor if your headache does not improve.

Nausea And Vomiting

Take M THYRONI 100MCG TABLET with a meal. Stick to simple meals. Avoid eating oily or spicy food. Contact your doctor if your vomiting does not improve.

WARNING & PRECAUTIONS

PREGNANCY

Safe

M THYRONI 100MCG TABLET can be used for women who are pregnant or are planning conception. Consult your doctor before taking it.

BREASTFEEDING

Safe

M THYRONI 100MCG TABLET can be used for breastfeeding women. Consult your doctor before taking it.

DRIVING AND USING MACHINES

Safe

M THYRONI 100MCG TABLET does not have any influence on the ability to drive or operate any machine.

KIDNEY

Consult your doctor

M THYRONI 100MCG TABLET does not have any significant effect on patients with kidney disease. Consult your doctor before taking it.

LIVER

Use with Caution

M THYRONI 100MCG TABLET should be used with caution in patients with liver disease due to impaired metabolism. Consult your doctor before taking it.

ALLERGY

Contraindicated

Do not take M THYRONI 100MCG TABLET if you are allergic to thyroxine or any other ingredients in this medicine.

HEART DISEASE

Use with Caution

M THYRONI 100MCG TABLET should be used with caution in patients with coronary heart disease such as acute myocardial infarction, acute myocarditis, acute pancarditis, angina pectoris, and hypertension. Consult your doctor before taking it.

USE IN PEDIATRICS

Contraindicated

M THYRONI 100MCG TABLET is not recommended for use in children and neonates under 2 years of age. Consult your doctor before taking it.

USE IN GERIATRICS

Use with Caution

M THYRONI 100MCG TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking M THYRONI 100MCG TABLET.

INTERACTIONS

A. Drug-drug interactions:

Before taking M THYRONI 100MCG TABLET, inform your doctor if you are taking any of the following medicines:

• cholestyramine, colestipol, clofibrate, simvastatin, and lovastatin (medicines used to manage high cholesterol levels in the blood)
• calcium, aluminium, magnesium, and iron supplements
• polystyrene sulfonates, kayexalate (used to manage high potassium levels in the blood)
• lanthanum, sevelamer (used to manage high phosphate levels in the blood)
• pantoprazole, rabeprazole, and sucralfate (medicines used to manage stomach ulcers)
• soya products and a high-fiber diet
• orlistat (a medicine used to reduce weight loss)
• propylthiouracil (used to manage hyperthyroidism)
• glucocorticoids (medicines used to manage inflammatory and autoimmune diseases) Ex. cortisone, prednisone
• propranolol (used to manage heart problems)
• lithium (used to manage mania)
• beta receptor blockers (medicines used to manage heart problems) Ex. propranolol, atenolol
• amiodarone (used to manage irregular heartbeats)
• iodinated contrast media (used in imaging techniques)
• salicylates (used to manage pain, fever, and inflammation) Ex. aspirin
• furosemide (used to manage heart problems)
• anticonvulsants such as carbamazepine and phenytoin (used to manage fits)
• oestrogen based contraceptives (medicines used to manage fertilization) Ex. ethinylestradiol, norethindrone
• sertraline, amitriptyline, and imipramine (medicines used to manage depression)
• chloroquine or proguanil (used to manage malaria)
• tyrosine kinase inhibitors (Ex. imatinib and sunitinib)
• barbiturates
• rifampicin (used to manage tuberculosis)
• St. John's Wort (Hypericum perforatum), an herbal medicine used to manage depression
• protease inhibitors, Ex. ritonavir (used to manage viral infections)
• methadone (used to manage pain)
• 5-flutouracil (used to manage cancer)
• Coumarin derivatives (medicines used to manage blood clotting) Ex. warfarin
• Digitalis (used to manage heart conditions)
• sympathomimetic agents (Ex. adrenaline), used to manage severe allergic reactions, cardiac arrest
• insulin or other anti-diabetic therapy Ex. metformin (used to manage diabetes mellitus)

Overdosage:

If you or anyone else accidentally took more M THYRONI 100MCG TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage may cause hyperthyroidism, and symptoms include agitation, confusion, irritability, hyperactivity, headache, sweating, mydriasis, fast heartbeat, irregular heartbeat, fast breathing, fever, increased bowel movements, and fits. Psychiatric symptoms associated with hyperthyroidism may also occur, including affectability, fatigue, anxiety, and nervousness. In severe cases, it causes a thyrotoxic crisis and leads to seizures, cardiac arrhythmias, heart failure, and coma.

SYNOPSIS

MORE INFORMATION

• Keep M THYRONI 100MCG TABLET out of the sight and reach of children
• Store M THYRONI 100MCG TABLET below 25°C

FAQs ABOUT M THYRONI 100MCG TABLET

Q: What if I forget to take M THYRONI 100MCG TABLET?

A: If you forgot to take a dose of M THYRONI 100MCG TABLET, take it as soon as you remember. However, if it is time for the next dose of M THYRONI 100MCG TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of M THYRONI 100MCG TABLET to compensate for the missed ones.

Q: Is M THYRONI 100MCG TABLET safe in pregnancy?

A: M THYRONI 100MCG TABLET can be used safely in pregnant women and requires dose adjustment. Inform your doctor if you are pregnant or planning to be pregnant before taking this medicine.

Q: What are the side effects of taking M THYRONI 100MCG TABLET?

A: The most common side effects of taking M THYRONI 100MCG TABLET are increased appetite, weight variations, headache, vomiting, diarrhea, changes in the menstrual cycle, fever, sensitivity to heat, cramps, and mood swings. Consult your doctor if any of the side effects worsen.

Q: What is the best time to take M THYRONI 100MCG TABLET?

A: Take M THYRONI 100MCG TABLET in the morning on an empty stomach at least half an hour before breakfast or as directed by the physician. Swallow the medicine with a glass of water. Do not chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.

Q: Who should not take M THYRONI 100MCG TABLET?

A: M THYRONI 100MCG TABLET is not recommended for use if you have untreated hyperthyroidism, untreated subclinical or overt thyrotoxicosis, untreated adrenal insufficiency, or pituitary insufficiency. Consult your doctor before taking it.

REFERENCES

1. KD. Tripathi. Thyroid hormones and thyroid inhibitors. Essentials of medical pharmacology. Eight edition. 2019. Page – 273.

2. Mateo RCI, Hennessey JV. Thyroxine and treatment of hypothyroidism: seven decades of experience. Endocrine. 2019. [Accessed on 13th January 2024]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794242/

3. GlaxoSmithKline Pharmaceuticals Limited. Thyroxine. [Revised in June 2023] [Accessed on 13th January 2024]. https://india-pharma.gsk.com/media/6368/eltroxin-tablets.pdf

4. Thyroxine sodium. Leeford Healthcare Ltd. [Accessed on 13th January 2024]. https://www.leeford.in/product/1115/thyroactiv-50

5. Drug bank. Levothyroxine. [Accessed on 13th January 2024]. https://go.drugbank.com/drugs/DB00451

USEFUL DIAGNOSTIC TESTS

• Thyroid Stimulating Hormone (TSH)
• Basic Thyroid Care
• Advance Thyroid Care
• Comprehensive Thyroid Care
• Thyroid Profile -Total (T3,T4&Tsh)
• Thyroid Profile- Free (Ft3, Ft4 & Tsh)
• Netmeds Thyroid Package
• Healthians Full Body Checkup With Thyroid And Cbc
• Thyroid Profile – C
• Thyroid Profile – A
• Thyroid Panel – 2
• Healthians Thyroid Test
• Thyroid Package – Advance
• Thyroid Package – Preventive
• Jaanch Thyroid Profile Advanced

AUTHOR DETAILS

Written By Dr. N. Sai Swaroop, Pharm.D
Last updated on 17 Jan 2024 | 12:54 PM(IST)