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INTRODUCTION LETHYROX 12.5MCG TABLET contains Levothyroxine which belong to the group of medicines known as Thyroid hormones. It is a synthetic thyroid hormone which is chemically identical to thyroxine produced by the thyroid gland. It helps in replacing missing thyroid hormone and in all for...
LETHYROX 12.5MCG TABLET contains Levothyroxine which belong to the group of medicines known as Thyroid hormones. It is a synthetic thyroid hormone which is chemically identical to thyroxine produced by the thyroid gland. It helps in replacing missing thyroid hormone and in all forms of underactive thyroid function (hypothyroidism) or after the removal of the thyroid gland. Thyroid hormone is vital for the normal growth and development. Lack of right number of thyroid hormones leads to slowing down in natural functions of our body.
Hypothyroidism is a condition where enough thyroid hormone required are not produced by the body. Some of the most common symptoms of hypothyroidism are tiredness, weight gain and feeling depressed. LETHYROX 12.5MCG TABLET helps in replacing the thyroxine that your thyroid gland cannot produce and prevent the symptoms of hypothyroidism.
Always take LETHYROX 12.5MCG TABLET exactly as prescribed by your doctor. Before taking this medicine tell your doctor if you have or ever had kidney disease, heart disease, or pancreas problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.
The most common side effects such as restlessness, insomnia, diarrhea, changes in menstrual cycle in women. Consult your doctor for advice if you experience any above side effects or it persists for a longer duration.
It helps:
LETHYROX 12.5MCG TABLET is a synthetic thyroid hormone which is identical to natural occurring thyroid hormone thyroxine or T4, produced by the thyroid gland. Thyroxine regulates the production of another hormone called thyroid stimulating hormone (TSH) which in turn controls how much thyroxine is produced. Levothyroxine regulates TSH production in the same way and therefore, substitutes for a lack of endogenous thyroxine (produced by the thyroid gland).
Take LETHYROX 12.5MCG TABLET exactly as prescribed by your doctor. Swallow the medicine with a glass of water. Do not chew or crush the medicine. Your doctor will prescribe the right dose depends on your age, body weight and disease condition.
Stop taking and consult your doctor immediately if you experience the following:
Drink lots of fluid, such as water or squash, to avoid dehydration. Do not take any other medicines without consulting your doctor.
Take rest and drink plenty of fluids. Apply a cold, wet cloth or ice pack to your forehead. Rest in a quiet, comfortable, dark room.
Eat a healthy diet includes enough calcium and vitamin D. Maintain healthy weight to ease stress and strain on your joints. Exercise regularly.
Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
LETHYROX 12.5MCG TABLET is not recommended for use in pregnant women unless necessary. Consult your doctor for advice.
LETHYROX 12.5MCG TABLET is not recommended for use in breastfeeding women unless necessary. Consult your doctor for advice.
Consumption of alcohol is not recommended during treatment with LETHYROX 12.5MCG TABLET.
LETHYROX 12.5MCG TABLET should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
LETHYROX 12.5MCG TABLET should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
Do not take this medicine if you are allergic (hypersensitive) to Levothyroxine or any other ingredients of this medicine.
LETHYROX 12.5MCG TABLET is not recommended in patients with myocardial infarction, acute inflammation of the heart muscle and acute inflammation of heart walls. It should be taken with caution in patients with severe heart disease. Consult your doctor for advice.
Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition.
LETHYROX 12.5MCG TABLET is not recommended if you:
Before taking LETHYROX 12.5MCG TABLET, inform your doctor if you have:
A. Drug-Drug Interaction:
Tell your doctor if you are taking or recently taken any other medicines, including medicines obtained without a prescription or the following:
Overdosage:
If you or anyone else accidentally takes too much of LETHYROX 12.5MCG TABLET consult your doctor immediately or visit the nearby hospital. Signs of an overdose may include fever, chest pain (angina), racing or irregular heartbeat, muscle cramps, headache, restlessness, flushing, sweating, diarrhoea, shaking (tremor), difficulty sleeping (insomnia) and very high temperature (hyperpyrexia).
| Drug | : | Levothyroxine sodium |
| Pharmacological Category | : |
Synthetic Thyroid Hormone |
| Therapeutic Indication | : | Hypothyroidism |
| Dosage Forms | : | Tablet |
A: It helps in replacing the thyroxine that the thyroid gland cannot produce and also helps to manage the symptoms of hypothyroidism.
A: The absorption of this medicine in the gut is decreased when taking with some foods and other medicines. Hence patients are usually instructed to take on an empty stomach 30-60 minutes before food intake to avoid erratic absorption of this medicine.
A: Take LETHYROX 12.5MCG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration depending upon your age, body weight and disease condition.
A: If you forgot to take a dose of LETHYROX 12.5MCG TABLET, take it as soon as you remember. However, if it is time for the next dose of LETHYROX 12.5MCG TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of LETHYROX 12.5MCG TABLET to compensate the missed ones.
A: No. You should not stop taking LETHYROX 12.5MCG TABLET without consulting the doctor because it may cause some side effects.
A: No, taking a higher dose of LETHYROX 12.5MCG TABLET will not be effective. Always stick to the dose and duration prescribed by your doctor.
A: LETHYROX 12.5MCG TABLET is not recommended for patients with heart problems. Consult your doctor for advice.
A: LETHYROX 12.5MCG TABLET should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.
1. KD. Tripathi. Hormones and related drugs. Essentials of medical pharmacology. Eighth edition. 2013. Page – 384.
2. Goodman and Gilman’s: The Pharmacological Basis of Therapeutics. Chapter – 39; Thyroid and antithyroid drugs; 12th ed. New York, New York: McGraw-Hill Medical, 2011. Page – 1130.
3. Roselyn Cristelle I. Mateo and James V. Hennessey; Thyroxine and treatment of hypothyroidism: seven decades of experience. [Published on 2019] [Accessed on January 19th, 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794242/
4. Philippe Colucci, Corinne Seng Yue, Murray Ducharme and Salvatore Benvenga; A Review of the Pharmacokinetics of Levothyroxine for the Treatment of Hypothyroidism; [Published on 2013] [Accessed on January 19th, 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193522/
5. Accord, Barnstaple, U.K.; Electronic Medicines Compendium (EMC); [Revised on Feb 2020] [Accessed on January 19th, 2024] https://www.medicines.org.uk/emc/files/pil.5805.pdf
6. Custom Pharmaceuticals Ltd., Health products regulatory authority (HPRA); [Revised on July 2014] [Accessed on January 19th, 2024] https://www.hpra.ie/img/uploaded/swedocuments/2138853.PPA1151_064_001.c4cad-f9b6-4592-8f62-e5117afd1ebe.000001Eltroxin%20Combined%20PIL.140708.pdf
Written By Dr. Janet.C, Pharm.D
Last updated on 19 Jan 2024 | 04:25 PM(IST)