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INTRODUCTION CARBIROSE 5 TABLET contains Carbimazole which belongs to the group of medicines called Antithyroid agents. It is used to reduce the formation of thyroid hormones in adults and children with an overactive thyroid gland (Hyperthyroidism). This medicine is also helps to restore the n...
CARBIROSE 5 TABLET contains Carbimazole which belongs to the group of medicines called Antithyroid agents. It is used to reduce the formation of thyroid hormones in adults and children with an overactive thyroid gland (Hyperthyroidism). This medicine is also helps to restore the normal function of the thyroid before its partial removal by surgery.
Your doctor may take blood or liver tests to determine how you are responding to the treatment. CARBIROSE 5 TABLET is not recommended for use in patients with severe liver, blood disorders or history of inflammation of the pancreas (acute pancreatitis). Before taking CARBIROSE 5 TABLET inform your doctor if you have bone marrow depression, mild or moderate liver problems, swelling in neck called an intrathoracic goiter or intolerant to certain sugars.
CARBIROSE 5 TABLET should be used with caution in pregnant women as it can harm the unborn baby. It is not recommended for use in breast-feeding women. Consult your doctor before taking. CARBIROSE 5 TABLET is not recommended for use in children below 2 years of age and should be used with caution in elderly patients above 65 years of age. The common side effects of taking CARBIROSE 5 TABLET are nausea, headache, arthralgia, mild gastric distress, skin rashes and pruritus. Contact your doctor if you experience any above side effects or persists for a longer duration.
CARBIROSE 5 TABLET consists of Carbimazole, a thionamide, is a pro-drug which undergoes rapid and virtually complete metabolism to the active metabolite, thiamazole, also known as methimazole. The method of action is believed to be inhibition of the organification of iodide and the coupling of iodothyronine residues which in turn suppress the synthesis of thyroid hormones.
Take CARBIROSE 5 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Stop taking CARBIROSE 5 TABLET and consult your doctor immediately if you experience any of the following side effects:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Consult your doctor if your headache worsens.
Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your vomiting worsens.
CARBIROSE 5 TABLET should be used with caution in pregnant women or women planning to have a baby. It will be given to you only if the potential benefit outweighs the potential risk to you and your unborn baby. Consult your doctor before taking it.
CARBIROSE 5 TABLET is generally not recommended for use in breastfeeding women as it may pass through breast milk. Consult your doctor before taking it.
Do not drive or operate any machines if you experience any unusual effects after taking CARBIROSE 5 TABLET.
CARBIROSE 5 TABLET is not recommended for use in patients with severe liver disease. It should be used with caution in patients with mild to moderate liver disease. Consult your doctor before taking it.
Do not take CARBIROSE 5 TABLET if you are allergic to Carbimazole or any other ingredients of this medicine.
CARBIROSE 5 TABLET is not recommended for use in children below 2 years of age. Consult your doctor before taking the medicine.
CARBIROSE 5 TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking the medicine.
CARBIROSE 5 TABLET is not recommended for use if you:
Before taking CARBIROSE 5 TABLET inform your doctor if you:
A, Drug-Drug interactions:
Before taking CARBIROSE 5 TABLET, inform your doctor if you are taking any of the following medicine:
Overdosage:
If you or anyone else accidentally takes too much of CARBIROSE 5 TABLET, consult your doctor immediately or visit the nearest hospital.
| Drug | : | Carbimazole |
| Pharmacological Category | : | Sulfur-containing imidazole derivative agents |
| Therapeutic Indication | : | Used to manage hypertension |
| Dosage Forms | : | Tablet |
A: CARBIROSE 5 TABLET is not recommended for use in patients with severe liver disease. It should be used with caution in patients with mild to moderate liver disease. Consult your doctor before taking the medicine.
A: CARBIROSE 5 TABLET is used to reduce the formation of thyroid hormones in adults and children with an overactive thyroid gland (Hyperthyroidism). This medicine is also helps to restore the normal function of the thyroid before its partial removal by surgery.
A: Yes, CARBIROSE 5 TABLET may cause tiredness in some individual. Consult your doctor for advice if you experience any side effects after taking the medicine.
A: CARBIROSE 5 TABLET consists of Carbimazole, a thionamide, is a pro-drug which undergoes rapid and virtually complete metabolism to the active metabolite, thiamazole, also known as methimazole. The method of action is believed to be inhibition of the organification of iodide and the coupling of iodothyronine residues which in turn suppress the synthesis of thyroid hormones.
A: During treatment follow regular blood tests to monitor the thyroid hormone levels. The most common side effects are feeling sick, upset stomach, headache, joint pain, skin rash and itching. Consult your doctor for advice if you experience unusual side effects for a longer duration.
A: CARBIROSE 5 TABLET may cause sleepiness in some individuals. Hence, these side effects may subside on their own. If they bothers for a longer time or worsen, consult your doctor for advice.
A: CARBIROSE 5 TABLET is the drug of choice for graves hyperthyroidism, and will usually decrease the thyroid hormone concentration to normal levels over 4–8 weeks. Always consult your doctor before taking the medicine.
A: CARBIROSE 5 TABLET may cause joint pain and an itchy rash. It acutely reduce the white cell count in the body and thus reduce the body's ability to fight infections.
A: If you have any kidney diseases or conditions, consult your doctor before taking the medicine.
A: If you have started taking CARBIROSE 5 TABLET the dose of warfarin may need adjustment. Consult your doctor and get your bleeding time checked so that the dose can be adjusted according to the results of the investigations.
1. Gregory A. Brent and Ronald J. Koenig. Thyroid and Antithyroid Drugs. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical. 2018. Page – 787-801.
2. Chiu Chi Tsang,Wai Shan Hui, Kwun Man Lo, Jonas Hon Ming Yeung, and Yuk Lun Cheng. Anti-Thyroid Drugs-Related Myopathy: Is Carbimazole the Real Culprit? National Library of Medicine, National center for biotechnology information. PubMed central. January 2015 [Accessed on January 06th, 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338648/
3. Henry B Burch and David S Cooper. Antithyroid drug therapy: 70 years later. European journal of Endocrinology. November 2018. [Accessed on January 06th, 2024] https://eje.bioscientifica.com/view/journals/eje/179/5/EJE-18-0678.xml
4. Tioarma B.V. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on January 06th, 2024] https://www.medicines.org.uk/emc/files/pil.10283.pdf
5. Central Pharma (Contract Packing) Limited. Electronic Medicines Compendium (EMC). [Revised in November 2020] [Accessed on January 06th, 2024] https://www.medicines.org.uk/emc/files/pil.10328.pdf
Written By Dr. Janet.C, Pharm.D
Last updated on 12 Jan 2024 | 04:34 PM(IST)