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INTRODUCTION ALDACTONE 25MG TABLET contains Spironolactone which belongs to the group of medicines called Diuretics. It is used to treat fluid accumulation in the tissues due to heart disorders and in the abdominal cavity, severe heart failure (NYHA III-IV), and certain kidney disorders....
ALDACTONE 25MG TABLET contains Spironolactone which belongs to the group of medicines called Diuretics. It is used to treat fluid accumulation in the tissues due to heart disorders and in the abdominal cavity, severe heart failure (NYHA III-IV), and certain kidney disorders.
ALDACTONE 25MG TABLET is also used to treat high blood pressure along with a salt-free diet and diuretics. It can also be used to diagnose and treat Conn’s disease (a disorder in which excess levels of aldosterone is produced in the adrenal cortex).
Fluid regularly drains into body tissues from the blood. When this fluid isn’t removed from the tissue, fluid retention (edema) occurs, causing symptoms like swelling and aching of affected body parts such as feet, ankles, or hands.
Prior to the treatment, your doctor may want you to take several tests to understand your existing condition.
Avoid consumption of alcohol during treatment with ALDACTONE 25MG TABLET. Before taking ALDACTONE 25MG TABLET, inform your doctor if you have any liver, heart, or kidney problems, or low sodium and high potassium levels.
ALDACTONE 25MG TABLET is not recommended for use among pregnant women. It should be used in breastfeeding women only if specifically directed by your doctor, therefore consult your doctor before taking it.
ALDACTONE 25MG TABLET is not recommended for use in children with moderate to severe kidney disease. It should be used with caution in elderly patients especially in patients having kidney diseases. Consult with your doctor.
The most common side effects of taking ALDACTONE 25MG TABLET are enlarged breasts in men, headache, indigestion, diarrhea, extreme tiredness, and drowsiness. Contact your doctor if any of the symptoms worsen.
Treats,
ALDACTONE 25MG TABLET works by competitively binding to receptors at the aldosterone-dependent sodium-potassium exchange site in the kidney tubules, causing increased amounts of sodium and water to be excreted, while retaining potassium.
Take ALDACTONE 25MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking ALDACTONE 25MG TABLET unless your doctor advises you to stop.
Stop taking ALDACTONE 25MG TABLET and contact your doctor immediately if you experience any of the following side effects:
Diarrhea:
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Ask for your doctor’s advice if diarrhea doesn’t improve.
Nausea:
Take ALDACTONE 25MG TABLET with or after meals. Stick to simple meals while taking this medicine. Avoid eating rich or spicy food. Do not take any medication on your own. Ask for your doctor’s advice if nausea doesn’t improve.
Headache:
Try to take rest and don’t involve yourself in exertive activities. Rest in a quiet and dark room. Apply a pain-relieving balm on your forehead. Ask for your doctor’s advice if headache doesn’t improve
Vomiting:
Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, oily, or sweet foods. Avoid carbonated drinks. Ask for your doctor’s advice if vomiting doesn’t improve.
ALDACTONE 25MG TABLET is not recommended for use in pregnant women. Consult your doctor before taking it.
ALDACTONE 25MG TABLET should be used in breastfeeding women only if specifically directed by your doctor. Consult your doctor before taking it.
Do not drive or operate any machines if you experience dizziness, headache, or confusion after taking ALDACTONE 25MG TABLET.
Avoid consumption of alcohol during treatment with ALDACTONE 25MG TABLET.
ALDACTONE 25MG TABLET is not recommended for use in patients with severely impaired kidney function or a sudden or rapidly worsening kidney disease, including those in which no urine, or very little urine, is being produced. It should be used with caution in patients with other kidney disorders like severe renal dysfunction. Consult your doctor before taking ALDACTONE 25MG TABLET.
ALDACTONE 25MG TABLET should be used with caution in patients with severe liver disorders. Consult your doctor before taking it.
Do not take ALDACTONE 25MG TABLET if you are allergic to Spironolactone.
ALDACTONE 25MG TABLET is not recommended for use if you:
Use in pediatrics:
ALDACTONE 25MG TABLET is not recommended for use in children with moderate to severe kidney disease. It should be used with caution in children with hypertension. They should be treated under guidance of a paediatrician. Consult your child’s doctor before giving ALDACTONE 25MG TABLET to your child.
Use in geriatrics:
ALDACTONE 25MG TABLET should be used with caution in elderly patients, especially those with kidney impairment. Consult your doctor before taking it.
A. Drug - Drug interactions:
Before taking ALDACTONE 25MG TABLET, inform your doctor if you are taking any of the following medicine:
B. Drug - Food interaction:
Avoid having foods rich in potassium while taking ALDACTONE 25MG TABLET.
Overdosage:
If you or anyone else accidentally take too much of ALDACTONE 25MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include nausea, vomiting, drowsiness, confusion, skin rash or diarrhea.
| Drug | : | Spironolactone |
| Pharmacological Category | : | Potassium-sparing diuretic |
| Therapeutic Indication | : | Fluid retention, Hypertension, Heart failure, Kidney disorders, Conn’s disease |
| Dosage Forms | : | Tablet |
Can ALDACTONE 25MG TABLET be used in children?
ALDACTONE 25MG TABLET is not recommended for use in children with moderate to severe kidney disease. It should be used with caution in children with hypertension. They should be treated under guidance of a paediatrician. Your doctor will decide the correct dose or select a suitable alternative therapy for your child.
Can ALDACTONE 25MG TABLET cause erectile dysfunction?
Erectile dysfunction is an uncommon side effect of ALDACTONE 25MG TABLET. Consult your physician if you have trouble getting an erection or related symptoms.
Is ALDACTONE 25MG TABLET safe to use in pregnancy?
ALDACTONE 25MG TABLET is not recommended for use in pregnant women. So before taking ALDACTONE 25MG TABLET, inform your doctor if you are pregnant, think you might be pregnant, or planning to get pregnant.
Can I stop taking ALDACTONE 25MG TABLET?
Do not stop taking ALDACTONE 25MG TABLET unless your doctor advises you to stop. Your original symptoms may return if you stop taking it suddenly. Ask for your doctor’s advice if you wish to discontinue taking ALDACTONE 25MG TABLET.
Can ALDACTONE 25MG TABLET be crushed?
ALDACTONE 25MG TABLET should be generally swallowed wholly with a glass of water, but to make it easier for children to take, the medicine may first be ground or crushed and then mixed in a glass of water by stirring. If you have any further doubts regarding use of ALDACTONE 25MG TABLET, contact your doctor.
What if I forget to take a dose of ALDACTONE 25MG TABLET?
If you forget to take a dose of ALDACTONE 25MG TABLET, take it as soon as you remember, and then continue your treatment as usual. Do not take the medicine twice to make up for the forgotten dose. If you have any further doubts regarding use of ALDACTONE 25MG TABLET, contact your doctor.
1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Hypertension. Pharmacotherapy Handbook. Ninth edition. Page- 87.
2. Andreas P Kalogeropoulos,, Jincy Thankachen, Javed Butler, James C Fang. Diuretic and renal effects of spironolactone and heart failure hospitalizations: a TOPCAT Americas analysis. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubmed.gov. September 2020. [Accessed 27th May 2022] https://pubmed.ncbi.nlm.nih.gov/32469156/
3. Chen C, Zhu XY, Li D, Lin Q, Zhou K. Clinical efficacy and safety of spironolactone in patients with resistant hypertension: A systematic review and meta-analysis. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubmed.gov. August 2020. [Accessed 27th May 2022] https://pubmed.ncbi.nlm.nih.gov/32846786/
4. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed 27th May 2022] https://www.medicines.org.uk/emc/files/pil.5123.pdf
5. Pfizer Labs. Spironolactone. [Revised in February 2021] [Accessed 27th May 2022] https://labeling.pfizer.com/ShowLabeling.aspx?format=PDF&id=520
6. Fluid retention (oedema). Better Health Channel. [Accessed 27th May 2022] https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/Fluid-retention-oedema
Written By Dr. Priyanka Goel, BDS
Last updated on 02 Dec 2022 | 06:09 PM(IST)