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INTRODUCTION ACMETO XL 50 TABLET contains Metoprolol, which belongs to the group of medicines called Beta-blockers. It is used to treat high blood pressure, angina pectoris (chest pain), and heart failure. It is also used to treat arrhythmias or palpitations, and to prevent heart attacks and m...
ACMETO XL 50 TABLET contains Metoprolol, which belongs to the group of medicines called Beta-blockers. It is used to treat high blood pressure, angina pectoris (chest pain), and heart failure. It is also used to treat arrhythmias or palpitations, and to prevent heart attacks and migraines.
Avoid alcohol consumption while taking ACMETO XL 50 TABLET as it lowers blood pressure. ACMETO XL 50 TABLET is not recommended for use in patients with asthma, COPD, severe bradycardia, second or third-degree heart block, cardiogenic shock, decompensated cardiac failure, sick sinus syndrome (unless a permanent pacemaker is present) and untreated pheochromocytoma. ACMETO XL 50 TABLET should be used with caution in patients with diabetes, stroke, liver or kidney disease, myocardial infarction, angina pectoris, and heart failure.
ACMETO XL 50 TABLET is not recommended for use in pregnant women unless considered necessary. ACMETO XL 50 TABLET should be used with caution in breastfeeding women, as it may pass through breast milk. ACMETO XL 50 TABLET is not recommended for use in children less than 6 years of age. ACMETO XL 50 TABLET should be used with caution in elderly patients aged 65 years or above.
The most common side effects of taking ACMETO XL 50 TABLET are experiencing faints upon standing due to low blood pressure, tiredness, slow heartbeat, palpitations, dizziness, headache, cold hands, and feet, etc. Contact your physician if any of your symptoms get worse or persist.
Treats:
In hypertension, ACMETO XL 50 TABLET works by blocking the effect of adrenaline on the heart and decreasing cardiac output, also reducing the outflow of sympathetic neurons, and suppressing renin activity (normally responsible for the increase in blood pressure). Together, these actions lower blood pressure effectively.
In angina pectoris, ACMETO XL 50 TABLET works by blocking adrenaline effects on the heart and decreases the heart rate, blood pressure, and extent of heart contraction. It also reduces the oxygen requirements of the heart, providing relief from angina.
In heart failure, ACMETO XL 50 TABLET slows down the heart rate and makes it easier for the heart to pump blood around the body.
Take ACMETO XL 50 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Stop taking ACMETO XL 50 TABLET and contact your physician immediately if you experience any of the following side effects:
Headache:
Rest and relax. Drink plenty of fluids to keep yourself hydrated. Apply a pain-relieving balm on the head if necessary. Contact your doctor if your headache does not improve.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any machines if you feel dizzy. Do not drink alcohol, as it can aggravate your dizziness. Contact your doctor if your dizziness does not improve.
Nausea, vomiting:
Take the medicine with or just after a meal. Stick to simple meals. Avoid eating oily or spicy foods. Contact your doctor if nausea and vomiting do not improve.
Stomach pain:
Try to rest and relax. Eat small meals but take them frequently. Keep a heating pad on your stomach. Contact your doctor if the stomach pain gets worse.
Diarrhoea:
Drink lots of fluids, such as water or fruit juice, to keep you hydrated. Do not take any medicine on your own to treat diarrhoea. Contact your doctor if your diarrhoea does not improve.
Constipation:
Eat fiber-rich foods such as fresh fruits, vegetables, and cereals. Drink more water and exercise regularly. Contact your doctor if constipation does not improve.
Skin rash:
Avoid hot showers, as they may irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if the rashes get worse.
ACMETO XL 50 TABLET is not recommended for use in pregnant women unless considered necessary by your doctor. Contact your doctor before taking ACMETO XL 50 TABLET.
ACMETO XL 50 TABLET should be used with caution in breastfeeding women as it may pass through breast milk. Contact your doctor before taking ACMETO XL 50 TABLET.
Do not drive or operate any machines if you feel dizzy and tired after taking ACMETO XL 50 TABLET.
Avoid alcohol consumption while taking ACMETO XL 50 TABLET as it lowers your blood pressure.
ACMETO XL 50 TABLET should be used with caution in patients with kidney diseases such as abnormal function. Contact your doctor before taking ACMETO XL 50 TABLET.
ACMETO XL 50 TABLET should be used with caution in patients with liver diseases. Contact your doctor before taking ACMETO XL 50 TABLET.
Do not take ACMETO XL 50 TABLET if you are allergic to Metoprolol or any other ingredients in this medicine.
ACMETO XL 50 TABLET is not recommended for use in patients with bronchospastic diseases like asthma or COPD. Contact your doctor before taking ACMETO XL 50 TABLET.
ACMETO XL 50 TABLET is not recommended for use in patients with severe bradycardia, low blood pressure, second or third-degree heart block, cardiogenic shock, decompensated cardiac failure, or sick sinus syndrome (unless a permanent pacemaker is present) and should be used with caution in patients with 1st-degree heart block, myocardial infarction, angina pectoris, heart failure, diseases of the heart valve, or enlarged heart muscle. Contact your doctor before taking ACMETO XL 50 TABLET.
ACMETO XL 50 TABLET is not recommended for use if you have:
Before taking ACMETO XL 50 TABLET, inform your doctor if you have:
Use in paediatrics:
ACMETO XL 50 TABLET is not recommended for use in children less than 6 years of age. Contact your doctor before taking ACMETO XL 50 TABLET.
Use in geriatrics:
ACMETO XL 50 TABLET should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking ACMETO XL 50 TABLET.
A. Drug-Drug interactions:
Before taking ACMETO XL 50 TABLET, inform your doctor if you are taking any of the following medicine:
Overdosage:
If you or anyone else has accidentally taken too much of ACMETO XL 50 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea, vomiting, bluish discolouration of the skin, severe bradycardia, low blood pressure (fatigue, dizziness), atrioventricular block, heart failure, bronchospasm or shortness of breath, hypoxia, cardiac arrest, cardiogenic shock, impairment of consciousness or coma.
| Drug | : |
Metoprolol |
| Pharmacological Category | : |
Beta-blockers |
| Therapeutic Indication | : |
High blood pressure, Angina pectoris, Heart failure |
| Dosage Forms | : |
Tablet, Capsule, Injection |
How ACMETO XL 50 TABLET work?
In hypertension, ACMETO XL 50 TABLET works by blocking the effect of adrenaline on the heart and decreasing cardiac output, also reducing the outflow of sympathetic neurons and suppressing renin activity (normally responsible for an increase in blood pressure). Together, these actions lower blood pressure effectively.
In angina pectoris, ACMETO XL 50 TABLET works by blocking adrenaline effects on the heart and decreases the heart rate, blood pressure, and extent of heart contraction. It also reduces the oxygen requirements of the heart, providing relief from angina.
In heart failure, ACMETO XL 50 TABLET slows down the heart rate and makes it easier for the heart to pump blood around the body.
What is ACMETO XL 50 TABLET used for?
ACMETO XL 50 TABLET contains Metoprolol, which belongs to the group of medicines called Beta-blockers. It is used to treat high blood pressure, angina pectoris (chest pain), and heart failure. It is also used to treat arrhythmias or palpitations and to prevent heart attacks and migraines. Contact your doctor before taking ACMETO XL 50 TABLET.
Can ACMETO XL 50 TABLET be used for treating asthma?
ACMETO XL 50 TABLET is not recommended for use in patients with bronchospastic diseases like asthma or COPD. Contact your doctor before taking it.
Can ACMETO XL 50 TABLET cause high blood sugar?
Yes. ACMETO XL 50 TABLET may raise blood sugar levels and should be used with caution in patients with diabetes or low blood sugar. Contact your doctor before taking ACMETO XL 50 TABLET.
Can ACMETO XL 50 TABLET cause low blood pressure?
Yes. ACMETO XL 50 TABLET can cause low blood pressure and causes dizziness, headache, sweating, and faintness on standing up. Contact your doctor before taking ACMETO XL 50 TABLET.
Can I stop taking ACMETO XL 50 TABLET if I feel better?
Do not stop ACMETO XL 50 TABLET suddenly without informing your physician. As it may lead to an exacerbation of angina pectoris (chest pain) or myocardial infarction (heart attack). Contact your doctor before stop taking it.
1. K D Tripathi. Cardiovascular drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page - 523, 545, 564.
2. Bethesda (MD). Metoprolol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubMed, 2006. [Accessed on 30th June 2022] https://www.ncbi.nlm.nih.gov/books/NBK501156/
3. Jason Morris, Alexis Dunham. Metoprolol. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov, January 2022. [Accessed on 30th June 2022] https://www.ncbi.nlm.nih.gov/books/NBK532923/
4. Aralez Pharmaceuticals US Inc. Metoprolol. [Revised in December 2016] [Accessed on 30th June 2022] https://www.toprol-xlhcp.com/assets/Toprol-PI-Clean.pdf
5. Dr Reddy’s Laboratories Limited. Metoprolol. [Revised in April 2016] [Accessed on 30th June 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4d382c97-704d-1603-e054-00144ff8d46c
6. STADA Arzneimittel AG. Metoprolol. [Accessed on 30th June 2022] https://file.wuxuwang.com/hma/DK_H_1308_001_FinalPL.pdf
Written By Dr. Dhivakaran R, BDS
Last updated on 01 Oct 2022 | 03:38 PM(IST)