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INTRODUCTION ADVASTAT GOLD 10 TABLET is a combination of Aspirin, Clopidogrel and Rosuvastatin which belongs to the group of medicines called Antiplatelets and HMG-CoA reductase inhibitors respectively. ADVASTAT GOLD 10 TABLET is indicated for the treatment of acute coronary syndrome, myocardi...
ADVASTAT GOLD 10 TABLET is a combination of Aspirin, Clopidogrel and Rosuvastatin which belongs to the group of medicines called Antiplatelets and HMG-CoA reductase inhibitors respectively. ADVASTAT GOLD 10 TABLET is indicated for the treatment of acute coronary syndrome, myocardial infarction (heart attack), angina (chest pain) or stroke (reduced blood supply to brain leading to brain death) that were caused due to clot or plaque formation in the blood vessels supplying the heart.
Acute coronary syndrome is a heart condition caused by plaque rupture or clot formation in the coronary arteries. Symptoms include heart attack, chest pressure or pain while at rest, shortness of breath and sweating.
Along treatment with ADVASTAT GOLD 10 TABLET follow a healthy low-fat diet as advised by doctor to achieve better results.
Avoid drinking alcohol during the therapy, as it could increase the risk of bleeding in the gastrointestinal tract. ADVASTAT GOLD 10 TABLET is not recommended for use in patients having severe liver, kidney or heart disease. Consult your doctor before taking this medicine.
ADVASTAT GOLD 10 TABLET is generally not recommended for use in pregnant or breastfeeding women and in children (below 18 years). Consult your doctor for an alternative therapy.
The most common side effects of taking ADVASTAT GOLD 10 TABLET are increased bleeding tendency, nausea, indigestion, diarrhea, stomach pain, constipation, muscle pain, dizziness and headache. Contact your doctor if any of these symptoms worsen.
ADVASTAT GOLD 10 TABLET effectively improves cardiac function and reduces the risk of heart problems, where clopidogrel acts by inhibiting platelet aggregation in the coronary arteries, aspirin acts by blocking the actions of an enzyme called cyclo-oxygenase 1 which is believed to be responsible for catalyzing the synthesis of platelets and rosuvastatin acts by inhibiting the action of an enzyme called HMG-CoA reductase, which is required to catalyze the formation of cholesterol, thus preventing clot or plaque formation in the coronary arteries leading to an uninterrupted supply of oxygen and blood to the heart.
Take ADVASTAT GOLD 10 TABLET as advised by your physician. Swallow ADVASTAT GOLD 10 TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Stop taking ADVASTAT GOLD 10 TABLET and contact your doctor immediately if you experience any of the following side effects:
Nausea and vomiting:
Try to take ADVASTAT GOLD 10 TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom did not improve.
Diarrhea:
Drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom did not improve.
Headache:
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.
Constipation :
Eat fiber rich foods such as fresh fruits, vegetables and cereals and drink plenty of water. Try to exercise more regularly. Consult your doctor if the symptom did not improve on its own.
Stomach pain:
Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom did not improve on its own.
ADVASTAT GOLD 10 TABLET is not recommended for use in pregnant women. However, consult your doctor before taking ADVASTAT GOLD 10 TABLET. Women of child-bearing potential should use suitable contraceptive method to avoid pregnancy while taking ADVASTAT GOLD 10 TABLET.
ADVASTAT GOLD 10 TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking ADVASTAT GOLD 10 TABLET.
ADVASTAT GOLD 10 TABLET does not affect your ability to drive or operate machines. However, if you experience dizziness during treatment with ADVASTAT GOLD 10 TABLET, do not drive or operate any machines. Consult your doctor before taking ADVASTAT GOLD 10 TABLET.
Avoid consumption of alcohol while taking ADVASTAT GOLD 10 TABLET as it may increase the risk of stomach bleeding and aggravate your existing condition.
ADVASTAT GOLD 10 TABLET is not recommended for use in patients having moderate-to-severe kidney disease and ADVASTAT GOLD 10 TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking ADVASTAT GOLD 10 TABLET.
ADVASTAT GOLD 10 TABLET is not recommended for use in patients having severe liver disease and active liver disease (including persistent elevations of serum transaminases exceeding three times the upper limit) and ADVASTAT GOLD 10 TABLET should be used with caution in patients with history of liver disease. Consult your doctor before taking ADVASTAT GOLD 10 TABLET.
Do not take ADVASTAT GOLD 10 TABLET if you are allergic to Clopidogrel, Rosuvastatin, Aspirin or prostaglandin synthetase inhibitors (Ex. naproxen, ibuprofen, mefenamic acid and indomethacin).
ADVASTAT GOLD 10 TABLET should be used with caution in patients with interstitial lung disease or severe respiratory failure. Consult your doctor before taking ADVASTAT GOLD 10 TABLET.
ADVASTAT GOLD 10 TABLET is not recommended for use in patients with recent ischemic stroke. Consult your doctor before taking ADVASTAT GOLD 10 TABLET.
ADVASTAT GOLD 10 TABLET is not recommended for use if you:
Before taking ADVASTAT GOLD 10 TABLET, inform your doctor if you have:
Use in pediatrics:
ADVASTAT GOLD 10 TABLET is strictly not recommended for use in children under 6 years of age and generally not recommended for use in children and adolescents (under 18 years of age) unless prescribed by your physician due to increased risk of bleeding. Consult your doctor before taking ADVASTAT GOLD 10 TABLET.
Use in geriatrics:
ADVASTAT GOLD 10 TABLET should be used with caution in elderly patients (aged 70 years or above) because of increased risk of gastro-intestinal bleeding and perforation when used for prolonged duration (if prolonged therapy is essential, patients should be reviewed regularly). Consult your doctor before taking ADVASTAT GOLD 10 TABLET.
A. Drug-Drug interactions:
Before taking ADVASTAT GOLD 10 TABLET inform to your doctor, if you are taking any of these medicines:
Overdosage:
If you or anyone else take too much of ADVASTAT GOLD 10 TABLET, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms of ADVASTAT GOLD 10 TABLET might include increased bleeding, confusion, disorientation, coma, convulsions, vomiting, tinnitus (ringing in the ears), vertigo (spinning sensation), sweating, warm extremities with bounding pulses, increased respiratory rate and hyperventilation.
| Drug | : | Aspirin, Clopidogrel, Rosuvastatin |
| Pharmacological Category | : |
Antiplatelets, HMG-CoA reductase inhibitors |
| Therapeutic Indication | : |
Acute coronary syndrome, Myocardial infarction, Angina, Stroke |
| Dosage Forms | : | Tablet, Capsule |
Can ADVASTAT GOLD 10 TABLET make me bleed more?
Yes. ADVASTAT GOLD 10 TABLET can increase your tendency to bleed and therefore it should be used with caution in patients having bleeding disorders like hemophilia, bleeding in the gut, brain or under the skin or others. While taking ADVASTAT GOLD 10 TABLET if you experience any symptoms like blood in vomit or urine, coughing up blood, black stools or purple spots under the skin, contact your doctor immediately as it could be a sign of severe internal bleeding.
Can ADVASTAT GOLD 10 TABLET be taken during periods?
ADVASTAT GOLD 10 TABLET generally can increase your tendency to bleed and if taken during periods, it may cause heavy menstrual bleeding. Consult your doctor before taking ADVASTAT GOLD 10 TABLET. Your doctor might either ask you to discontinue the treatment with ADVASTAT GOLD 10 TABLET for some time or may suggest an alternative therapy to improve your disease condition.
Can I continue to take ADVASTAT GOLD 10 TABLET before any planned surgeries?
No. Avoid taking ADVASTAT GOLD 10 TABLET if you are going to undergo any surgery (including dental surgery) because this medicine can make you bleed more than usual. Your doctor might either ask you to discontinue the treatment with ADVASTAT GOLD 10 TABLET for some time or may suggest an alternative therapy to improve your disease condition.
Can ADVASTAT GOLD 10 TABLET be used in children?
No. ADVASTAT GOLD 10 TABLET is not recommended for use in children and adolescents (under 18 years) unless prescribed by your physician. ADVASTAT GOLD 10 TABLET is strictly not recommended for use in children aged less than 6 years due to risk of increased side effects. Consult your doctor before taking ADVASTAT GOLD 10 TABLET.
Can I try to get pregnant while taking ADVASTAT GOLD 10 TABLET?
No. ADVASTAT GOLD 10 TABLET should be discontinued from use if you are trying to get pregnant because, it may cause severe abnormalities to the growing fetus. Also, it is advised that women of child-bearing potential should use suitable contraceptive method to avoid pregnancy while taking ADVASTAT GOLD 10 TABLET.
Can I consume alcohol while taking ADVASTAT GOLD 10 TABLET?
No. Avoid consumption of alcohol while taking ADVASTAT GOLD 10 TABLET as it could aggravate your existing disease condition and increase the risk of bleeding. Before taking ADVASTAT GOLD 10 TABLET inform your doctor if you are alcoholic or have history of alcohol abuse.
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Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 25 Oct 2022 | 06:32 PM(IST)