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INTRODUCTION ADVASTAT CV 20MG CAPSULE is a combination of Clopidogrel and Rosuvastatin which belongs to the group of medicines called Antiplatelets and HMG-CoA reductase inhibitors respectively. ADVASTAT CV 20MG CAPSULE is indicated for the treatment and prevention of cardiovascular diseases s...
ADVASTAT CV 20MG CAPSULE is a combination of Clopidogrel and Rosuvastatin which belongs to the group of medicines called Antiplatelets and HMG-CoA reductase inhibitors respectively. ADVASTAT CV 20MG CAPSULE is indicated for the treatment and prevention of cardiovascular diseases such as acute coronary syndrome, myocardial infarction (also known as a heart attack), angina (chest pain due to inadequate blood supply to the heart) and stroke (reduced blood supply to the brain leading to brain death), among patients with elevated cholesterol and/or triglyceride levels along with a suitable diet, exercise and weight management regimen.
An acute coronary syndrome is a heart condition caused by plaque rupture or clot formation in the coronary arteries. Symptoms include heart attack, chest pressure or pain while at rest, shortness of breath and sweating.
During and prior to treatment with ADVASTAT CV 20MG CAPSULE, your doctor would recommend several blood tests to check your liver function.
ADVASTAT CV 20MG CAPSULE generally increases your tendency to bleed and so if you cut or injure yourself, it may take a little longer for the bleeding to stop. Bleeding for minor injuries like small cut or shaving is of no concern.
However, if you experience excessive bleeding for a prolonged period, contact your doctor. Before taking ADVASTAT CV 20MG CAPSULE inform your doctor if you have any liver, kidney or lung disease.
ADVASTAT CV 20MG CAPSULE is generally not suitable for use in pregnant or breastfeeding women and in children or adolescents (aged below 18 years). ADVASTAT CV 20MG CAPSULE should be used with caution in elderly patients (aged 65 years or above).
The most common side effects of taking ADVASTAT CV 20MG CAPSULE are headache, dizziness, nausea, stomach pain or increased bleeding tendency. Consult your doctor if any of the side effects worsen.
ADVASTAT CV 20MG CAPSULE reduces the risk of heart problems, where clopidogrel acts by irreversibly inhibiting the aggregation of platelet in the coronary arteries and rosuvastatin acts by inhibiting the action of an enzyme called HMG-CoA reductase which is responsible for catalyzing cholesterol biosynthesis in the body, thus reducing the chances of plaque formation/blood clots in the coronary arteries leading to the prevention of fatal cardiac outcomes.
Take ADVASTAT CV 20MG CAPSULE as advised by your physician. Swallow ADVASTAT CV 20MG CAPSULE with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
Stop taking ADVASTAT CV 20MG CAPSULE and contact your doctor immediately if you experience any of the following side effects:
Nausea and vomiting:
Try to take ADVASTAT CV 20MG CAPSULE with or just after a meal or a snack. Stick to simple meals. Avoid eating oil-rich or spicy foods. Consult your doctor if the symptom did not improve.
Headache:
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.
Constipation :
Eat fibre-rich foods such as fresh fruits, vegetables, cereals and drink plenty of water. Try to exercise more regularly. Consult your doctor if the symptom did not improve on its own.
Stomach pain:
Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heating pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom did not improve on its own.
Skin rash:
Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if the symptom did not improve.
ADVASTAT CV 20MG CAPSULE is not recommended for use in pregnant women. Consult your doctor before taking this medicine. If you became pregnant while taking ADVASTAT CV 20MG CAPSULE, stop taking it and consult your doctor immediately. Women of child-bearing potential should use a suitable contraceptive method to avoid pregnancy while taking ADVASTAT CV 20MG CAPSULE.
ADVASTAT CV 20MG CAPSULE is not recommended for use in breastfeeding women. Consult your doctor before taking ADVASTAT CV 20MG CAPSULE.
Do not drive or operate any heavy tools or machines if you experience dizziness after taking ADVASTAT CV 20MG CAPSULE.
Avoid consumption of alcohol while taking ADVASTAT CV 20MG CAPSULE, as it could aggravate your existing disease condition.
ADVASTAT CV 20MG CAPSULE is not recommended for use in patients with severe kidney disease and should be used with caution in patients with kidney problems. Consult your doctor before taking ADVASTAT CV 20MG CAPSULE.
ADVASTAT CV 20MG CAPSULE is not recommended for use in patients with liver disease. Consult your doctor before taking ADVASTAT CV 20MG CAPSULE.
Do not take ADVASTAT CV 20MG CAPSULE if you are allergic to Clopidogrel or Rosuvastatin.
ADVASTAT CV 20MG CAPSULE should be taken with caution in patients with severe respiratory failure. Consult your doctor before taking ADVASTAT CV 20MG CAPSULE.
ADVASTAT CV 20MG CAPSULE is not recommended for use if you:
Before taking ADVASTAT CV 20MG CAPSULE, inform your physician if you:
Use in pediatrics:
ADVASTAT CV 20MG CAPSULE is not suitable for use in children and adolescents (aged below 18 years) due to risk of bleeding (such as stomach ulcer, blood disorders leading to bleeding into tissues, organs or joints of the body, recent serious injury, recent surgery (including dental), ischemic stroke (occurred within last 7 days), planned surgery (in next 7 days). It is strictly not recommended for use in children aged below 6 years. Consult your child’s doctor for advice.
Use in geriatrics:
ADVASTAT CV 20MG CAPSULE should be used with caution in elderly patients (aged 65 years or above). Proper dose adjustments and careful monitoring are required in such patients. Consult your doctor before taking ADVASTAT CV 20MG CAPSULE.
A. Drug-Drug interactions:
Before taking ADVASTAT CV 20MG CAPSULE inform your doctor, if you are taking any of these medicines:
Overdosage:
If you or anyone else accidentally take too much of ADVASTAT CV 20MG CAPSULE, contact your doctor immediately or go to a hospital straight away. Overdosage of ADVASTAT CV 20MG CAPSULE may lead to prolonged bleeding time and subsequent bleeding complications.
| Drug | : | Clopidogrel, Rosuvastatin |
| Pharmacological Category | : | Antiplatelets, HMG-CoA reductase inhibitors |
| Therapeutic Indication | : | Myocardial infarction, Angina, Acute coronary Syndrome and stroke |
| Dosage Forms | : | Tablet, Capsule |
Can I consume alcohol while taking [GBBNKEYWORD]?
No, avoid consumption of alcohol while taking ADVASTAT CV 20MG CAPSULE, as it could aggravate your existing disease condition. Follow the lifestyle modification suggested by your doctor such as quitting smoking or alcohol consumption during this therapy to achieve better results. Before taking ADVASTAT CV 20MG CAPSULE inform your doctor if you are an alcoholic.
Can ADVASTAT CV 20MG CAPSULE be taken during pregnancy?
No, ADVASTAT CV 20MG CAPSULE is not recommended for use in pregnant women. Consult your doctor before taking this medicine. If you become pregnant while taking ADVASTAT CV 20MG CAPSULE, stop taking it and consult your doctor immediately. Women of childbearing potential should use a suitable contraceptive method to avoid pregnancy while taking ADVASTAT CV 20MG CAPSULE.
Can ADVASTAT CV 20MG CAPSULE cause diabetes?
Yes, ADVASTAT CV 20MG CAPSULE can cause your blood sugar levels to increase, which is highly predominant among individuals who already have any risk factors for developing diabetes (such as being obese or overweight, having high blood pressure or having pre-diabetes). While taking ADVASTAT CV 20MG CAPSULE follow a low-carb diet and avoid smoking or consuming alcohol. Manage your body weight by doing regular physical activity as instructed by your doctor.
Can I take aspirin along with ADVASTAT CV 20MG CAPSULE?
Although the combination of aspirin with clopidogrel and rosuvastatin is considered safe, consult your doctor before taking ADVASTAT CV 20MG CAPSULE. Try to avoid the concomitant administration of other antiplatelet medicine without consulting your doctor. Your doctor will decide the correct dosing regimen for you depending on your health condition.
Can ADVASTAT CV 20MG CAPSULE prevent a heart attack?
Yes, ADVASTAT CV 20MG CAPSULE can prevent the incidence of heart attack. It acts by blocking the aggregation of platelets and by reducing plaque or clot formation in the blood vessels which contributes to the prophylactic effects of heart attack. Before taking ADVASTAT CV 20MG CAPSULE inform your doctor if you have pre-existing heart problems.
Can ADVASTAT CV 20MG CAPSULE cause blood in stool?
ADVASTAT CV 20MG CAPSULE generally increases your tendency to bleed and can cause black or blood-stained stools due to increased bleeding in the gut. If you have any existing condition that can make you bleed more (such as presence of stomach ulcer) please inform your doctor before taking ADVASTAT CV 20MG CAPSULE.
What to do If I forget to take ADVASTAT CV 20MG CAPSULE?
You should take ADVASTAT CV 20MG CAPSULE immediately when you remember. If it is time for your next dose of ADVASTAT CV 20MG CAPSULE skip the dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.
What is ADVASTAT CV 20MG CAPSULE used for?
ADVASTAT CV 20MG CAPSULE is used to treat and prevent the risk of cardiovascular diseases such as acute coronary syndrome, myocardial infarction, angina and stroke among patients with elevated cholesterol and triglyceride levels. Consult your doctor before taking ADVASTAT CV 20MG CAPSULE.
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Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 02 Dec 2022 | 12:47 PM(IST)