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INTRODUCTION P COOL CREAM contains Calamine, Lignocaine(lidocaine), and Phenylephrine which belong to the group of medicines called antipruritic, anaesthetics, and sympathomimetic agents. P COOL CREAM is used in adults to relieve pain and bleeding associated with piles, anal fissures, and hae...
P COOL CREAM contains Calamine, Lignocaine(lidocaine), and Phenylephrine which belong to the group of medicines called antipruritic, anaesthetics, and sympathomimetic agents. P COOL CREAM is used in adults to relieve pain and bleeding associated with piles, anal fissures, and haemorrhoids.
Piles (haemorrhoids) are tissue growth in and around the anus due to the enlargement of veins in the lower anus or rectum, which leads to discomfort such as pain, itching, blood in the stool, discomfort when pooping, etc. An anal fissure is a tear or cracks in the lining of the anus or anal canal with symptoms of severe pain while pooping, blood in the poop, etc.
P COOL CREAM is not recommended for use in areas of trauma (injury to the mucosa due to chemical, physical, or thermal injury) or patients with hypersensitivity to the ingredients. Before using P COOL CREAM, inform your doctor if you have any heart diseases, increased blood pressure, diabetes, an enlarged prostate gland, thyroid problems, etc.
P COOL CREAM should be used with caution in patients who are pregnant, breastfeeding, elderly, or have children. Possible side effects of P COOL CREAM are irritation, headache, rectal bleeding, anxiety, skin dryness, etc. Consult your doctor if any of the symptoms are worsening.
It is used in adults to relieve pain and bleeding associated with:
P COOL CREAM contains calamine, lignocaine (lidocaine), and phenylephrine. Calamine relieves itching and soothes the skin. When applied to the skin, the aqueous component of calamine lotion evaporates. The heat required for evaporation is taken from the body, which gives a cooling effect at the site of application.
Calamine has antibacterial properties, which help prevent infections. Phenylephrine is a decongestant that shrinks swollen blood vessels. Enlarged blood vessels result in piles, so phenylephrine helps treat the symptoms of burning, itching, and swelling associated with piles. Lidocaine blocks the pain alerts from the nerves to the brain, thereby decreasing the feeling of pain.
Always use P COOL CREAM as directed by your physician. It is for external use only. Do not use it on your eyes. Take a small amount of P COOL CREAM in a fingercot. Insert it slowly into the anal opening and apply with gentle rotation. You can also apply P COOL CREAM with a penta applicator.
For that, remove the cap of the tube and insert the Penta applicator into the tube. Insert this into the anal opening. Push the medicine from behind slowly. Remove the applicator and clean it after separating it from the tube. Do not share your applicator with anyone else. Your doctor will determine the required dose and duration of P COOL CREAM for you as per your age and disease condition.
Stop using P COOL CREAM and contact your doctor immediately if you notice any of the symptoms:
P COOL CREAM should be used with caution if you are pregnant, especially in early pregnancy where organogenesis (development of the organ in baby) takes place. Consult your doctor before using P COOL CREAM.
P COOL CREAM should be used with caution in breastfeeding women, as it may pass through the breast milk. Consult your doctor before using P COOL CREAM.
P COOL CREAM should be used with caution in patients who suffer from serious liver diseases as they are at risk of developing lidocaine toxicity. (Numbness, dizziness, tongue paresthesia etc.) Consult your doctor before using P COOL CREAM.
If you are allergic to calamine, lignocaine (lidocaine), phenylephrine, or any of the other ingredients in P COOL CREAM, do not use it. Consult your doctor before using P COOL CREAM.
P COOL CREAM should be used with caution in patients with pulmonary compromise (deterioration in respiratory function with a high likelihood of rapid progression to respiratory failure and death), as there is a higher chance of getting methemoglobinemia. Consult your doctor before using P COOL CREAM.
P COOL CREAM should be used with caution in patients suffering from heart diseases and increased blood pressure. Consult your doctor before using P COOL CREAM.
P COOL CREAM should be used with caution in children. Infants under 6 months of age are at a higher risk of developing methemoglobinemia (bluish discolouration of the skin, pallor, weakness, abnormal heart rate, comma etc.) while using P COOL CREAM. Consult your doctor before using it.
P COOL CREAM should be used with caution in elderly people. Consult your doctor before taking it.
P COOL CREAM is not recommended to use in:
Before using P COOL CREAM inform your doctor if you are having:
A. Drug-Drug interaction:
Before using P COOL CREAM inform your doctor if you are taking the following medicines:
Overdosage:
If you or anyone else accidentally use too much of P COOL CREAM, consult your doctor or visit the nearby hospital.
| Drug | : | Calamine, Lignocaine(lidocaine), Phenylephrine |
| Pharmacological Category | : |
Antipruritic, Anaesthetics, Sympathomimetic agents |
| Therapeutic Indication | : |
Used in adults to relieve pain and bleeding associated with piles, anal fissures, and haemorrhoids |
| Dosage Forms | : |
Cream |
Q: What is P COOL CREAM used for?
A: P COOL CREAM is used in adults to relieve pain and bleeding associated with piles, anal fissures, and haemorrhoids. Piles (haemorrhoids) are tissue growth in and around the anus due to the enlargement of veins in the lower anus or rectum, which leads to discomfort such as pain, itching, blood in the stool, discomfort when pooping, etc. An anal fissure is a tear or cracks in the lining of the anus or anal canal with symptoms of severe pain while pooping, blood in the poop, etc. consult a doctor before using P COOL CREAM.
Q: What are the possible side effects of using P COOL CREAM?
A: Possible side effects of P COOL CREAM are irritation, headache, rectal bleeding, anxiety, skin dryness, etc. Consult your doctor if any of the symptoms are worsening.
Q: How does P COOL CREAM work?
A: P COOL CREAM contains calamine, lignocaine (lidocaine), and phenylephrine. Calamine relieves itching and soothes the skin. When applied to the skin, the aqueous component of calamine lotion evaporates. The heat required for evaporation is taken from the body, which gives a cooling effect at the site of application.
Calamine has antibacterial properties, which help prevent infections. Phenylephrine is a decongestant that shrinks swollen blood vessels. Enlarged blood vessels result in piles, so phenylephrine helps treat the symptoms of burning, itching, and swelling associated with piles. Lidocaine blocks the pain alerts from the nerves to the brain, thereby decreasing the feeling of pain.
Q: How to use P COOL CREAM ?
A: Always use P COOL CREAM as directed by your physician. It is for external use only. Do not use it on your eyes. Avoid contact with the eyes, nose, and mouth. Take a small amount of P COOL CREAM in a fingercot. Slowly insert it inside the anal opening and apply it through gentle rotation. You can also apply P COOL CREAM with a penta applicator.
For that, remove the cap of the tube and insert the Penta applicator into the tube. Insert this into the anal opening. Push the medicine from behind slowly. Remove the applicator and clean it after separating it from the tube. Do not share your applicator with anyone else. Your doctor will determine the required dose and duration of P COOL CREAM for you as per your age and disease condition.
Q: What are the ingredients of P COOL CREAM?
A: P COOL CREAM contains 5% w/w calamine, 3% w/w lignocaine (lidocaine), 0.1% w/w phenylephrine, and 0.1% w/w chlorocresol as ingredients.
Q: Can I use P COOL CREAM if I am pregnant?
A: P COOL CREAM should be used with caution if you are pregnant, especially in early pregnancy where organogenesis (the development of organs in the baby) takes place. Consult your doctor before using P COOL CREAM.
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3. Cheetham, M. J., M. A. Kamm, and R. K. S. Phillips. Topical phenylephrine increases anal canal resting pressure in patients with faecal incontinence. Cheetham, M. J., M. A. Kamm, and R. K. S. Phillips. Topical phenylephrine increases anal canal resting pressure in patients with faecal incontinence. Gut 48, no. 3 (2001). [Published in March 2001] [Accessed on 5th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1760141/
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6. Medicaid. Lidocaine [Published on 1st April 2020][Accessed on 5th September 2022] https://www.medicaid.nv.gov/Downloads/provider/Topical_Analgesics_Antipruritics%202020-09.pdf
7. Mskcc. Phenylephrine. [Revised on 4th September 2022] [Accessed on 5th September 2022] https://www.mskcc.org/cancer-care/patient-education/phenylephrine-topical-01
8. Cigna health. Phenylephrine. [Revised on 23rd May 2018] [Accessed on 5th September 2022] https://www.cigna.com/knowledge-center/hw/medications/phenylephrine-d04298a1
9. Group pharmaceuticals. Calamine + lidocaine+ phenylephrine. [Accessed on 5th September 2022] https://www.grouppharma.com/multi-speciality/p-cool/
Written By Dr. Dhivakaran R, BDS
Last updated on 10 Mar 2023 | 05:16 PM(IST)