INTRODUCTION

SALBUTAMOL 2MG contains Calcium dobesilate which belongs to the group of medicines called Vasoprotective agents. It is used to treat microangiopathies such as diabetic retinopathy, hemorrhoidal syndrome (condition of inflamed and swollen blood vessels in rectum or around anus), chronic venous insufficiency/vascular dysfunction (condition of leg veins in which blood gets pooled in the legs due to failure of valves present in leg veins presenting with pain, cramps, and inactivity of legs) and adjuvant to superficial thrombophlebitis (causing clot in superficial veins), and other microcirculation disorders of arteriovenous origin.

Microangiopathy or microcirculation disorder is a disease of small blood vessels in which walls of those vessels become weak and bleed, resulting in reduced blood flow. In diabetic retinopathy, microangiopathy reduces the blood flow to retina, causing floaters (dark spots in the vision), blurred vision or even blindness.

SALBUTAMOL 2MG is not recommended for use in patients who are allergic to calcium dobesilate. It should be used with caution in patients with liver diseases such as obstructive jaundice, diabetic retinopathy (eye disorder that occurs due to diabetes), venous disorder such as varicose veins (enlarged veins in legs and feet), and dialysis patients with serious renal failure. SALBUTAMOL 2MG is not recommended for use in pregnant and breastfeeding women, also it should be used with caution in children and adolescents (below 18 years of age). Consult your doctor before taking it. The most common side effects associated with the use of SALBUTAMOL 2MG are fever, bloating, constipation, diarrhoea, pain, nausea, vomiting and arthralgia (joint pain). Consult your doctor if any of the symptom worsens.

USES OF SALBUTAMOL 2MG

• Treats microangiopathies especially in diabetic retinopathy
• Treats hemorrhoidal syndrome and chronic venous insufficiency
• Used as an adjuvant to superficial thrombophlebitis and also treats other microcirculation disorders

HOW SALBUTAMOL 2MG WORKS

SALBUTAMOL 2MG works by reducing the permeability or leakage in the blood vessels by acting on collagen chains, resulting in strengthening of the vessel walls which also reduces the action of the chemical messengers that increase the permeability of vessel walls, thereby resulting in reduced bleeding in small vessels.

DIRECTIONS FOR USE

Take SALBUTAMOL 2MG as advised by your physician. Swallow the medicine with a glass of water and take this medicine along with food. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF SALBUTAMOL 2MG

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink lot of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to treat diarrhoea and consult your doctor if the symptom gets worse.

Nausea and vomiting:

Try to take SALBUTAMOL 2MG with or just after a meal or a snack. Stick to simple meals. Avoid eating oily, fried or spicy foods. Consult your doctor if the symptom gets worse.

Itching:

Tap or pat your skin upon itching. Try not to scratch the itchy skin. Take cool or warm bath and place cool damp towel on the skin. Wear loose cotton clothes. Avoid using perfumed moisturizers, deodorants or soaps.

Constipation:

Take fiber rich foods in your diet such as fresh fruits, vegetables and whole grain cereals, and drink plenty of fluids. Exercise more regularly and stay active. Consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interactions:

Before taking SALBUTAMOL 2MG, inform your doctor if you are taking any medicines including prescription or non-prescription medicines, herbals or vitamin supplements.

Overdosage:

If you or anyone else accidentally takes too much of SALBUTAMOL 2MG, consult your doctor immediately or visit the nearby hospital if you experience any unusual symptoms.

SYNOPSIS

MORE INFORMATION

• Keep the medicine out of reach in children
• Store SALBUTAMOL 2MG at room temperature

FAQs ABOUT SALBUTAMOL 2MG

What is SALBUTAMOL 2MG used for?

SALBUTAMOL 2MG is used to treat microangiopathies such as diabetic retinopathy (loss of vision due to diabetes), hemorrhoidal syndrome (swelling of veins in lower rectum or anus), chronic venous insufficiency (presenting with pain, cramps, and inactivity of legs) and adjuvant to superficial thrombophlebitis, and other microcirculation disorders. Consult your doctor before taking SALBUTAMOL 2MG.

Is SALBUTAMOL 2MG safe to use in children and elderly?

SALBUTAMOL 2MG should be used with caution in children and adolescents (below 18 years of age) and in elderly patients (above 65 years of age). Consult your doctor for advice before taking SALBUTAMOL 2MG.

Is SALBUTAMOL 2MG safe to use in patients undergoing dialysis?

SALBUTAMOL 2MG should be used with caution in dialysis patients with serious renal failure. In such cases dose can be reduced accordingly. Consult your doctor for advice before taking SALBUTAMOL 2MG.

How does SALBUTAMOL 2MG work?

SALBUTAMOL 2MG helps in treating small blood vessel disorders and haemorrhoids, where calcium dobesilate works by reducing the permeability or leakage in the blood vessels by acting on collagen chains, resulting in strengthening of the vessel walls. It also reduces the action of the chemical messengers that increase the permeability of vessel walls, thereby resulting in reduced bleeding in small vessels.

Can SALBUTAMOL 2MG be taken during pregnancy or breast feeding?

SALBUTAMOL 2MG is not recommended for use in pregnant women unless it is clearly advised by your doctor. It is also not recommended for use in breastfeeding mothers as it may pass into breast milk. Consult your doctor before taking it.

When should I stop taking SALBUTAMOL 2MG?

Stop taking SALBUTAMOL 2MG and contact your doctor immediately, if you experience any signs of agranulocytosis (high fever, oral cavity infections, sore throat, and/or anogenital inflammation) and signs of infection (fever, chills, sweats and cough), skin rash, fever and bone pain.

REFERENCES

1. Laurence L Brunton, Bruce A Chubner, Bjorn C knollmann. Goodman & Gillman’s. The Pharmaceutical Basis of Therapeutics. Twelth edition. 2011. Page – 1247.

2. Yilmaz Unal, Salih Tuncal, Koray Kosmaz, Berkay Kucuk, Kemal Kismet, Turgut Cavusoglu, Pinar Celepli, Mehmet Senes, Selin Yildiz, Sema Hucumenoglu. The Effect of Calcium Dobesilate on Liver Damage in Experimental Obstructive Jaundice. NIH National Library of Medicine. National Centre for Biotechnology Information. PubMed.gov. April 2019. [Accessed on 8th July 2022] https://pubmed.ncbi.nlm.nih.gov/29589984/

3. E Rabe, K A Jaeger, M Bulitta, F Pannier. Calcium dobesilate in patients suffering from chronic venous insufficiency: a double-blind, placebo-controlled, clinical trial. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. June 2011. [Accessed on 8th July 2022] https://pubmed.ncbi.nlm.nih.gov/21478142/

4. Berko Ilac ve Kimya Sanayi A.S. X-ven 500 mg Capsules. [Revised in November 2017] [Accessed on 8th July 2022] https://berkoilac.com.tr/wp-content/uploads/2019/05/x-ven-PIL-revD.pdf

5. OM Pharma. Doxium 500. [Accessed on 8th July 2022] https://www.e-lactancia.org/media/papers/Dobesilate-DS-OMPharma2018.pdf

USEFUL DIAGNOSTIC TESTS

• Complete blood count