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INTRODUCTION AZARGA EYE DROPS is a combination of Brinzolamide and Timolol which belongs to the group of medicines called Ophthamic anti-glaucoma agents. It is used in adults to treat increased pressure in the eye caused due to glaucoma or ocular hypertension. It is typically used in patients...
AZARGA EYE DROPS is a combination of Brinzolamide and Timolol which belongs to the group of medicines called Ophthamic anti-glaucoma agents. It is used in adults to treat increased pressure in the eye caused due to glaucoma or ocular hypertension. It is typically used in patients who have not responded adequately to therapy with beta-blockers (Ex. timolol) alone.
AZARGA EYE DROPS is for ophthalmic use only. Instil few drops of the medicine into the affected eye(s). Do not touch the tip of the dropper with your eye or other body surface to avoid contamination. If you wear soft contact lenses, remove the lens before applying AZARGA EYE DROPS and wait for at least 15 minutes before reinsertion.
Before using AZARGA EYE DROPS inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have or previously had any breathing problems, asthma, COPD, diabetes, thyroid problems, low blood pressure or problems in blood circulation as a precaution.
Do not use AZARGA EYE DROPS without consulting your doctor if you are pregnant or breastfeeding. The most common side effects of using AZARGA EYE DROPS are burning or stinging of eyes, eye redness and itching, blurred vision and bitter taste. Consult your doctor if any of these side effect bothers you.
AZARGA EYE DROPS reduces intraocular pressure by decreasing the production of aqueous humour (a type of lubricating eye fluid) in the eye. As a result, it reduces strain on the eyes which therefore reduces elevated intraocular pressure.
Use AZARGA EYE DROPS as advised by your physician. It is for ophthalmic use only. Wash your hands before and after application. Tilt your head slightly and gently pull the lower eyelid downwards.
Instil few drops of the medicine into the affected eye(s). Close your eyes and press the corner of your eye with your finger for a minute. Do not touch the tip of the dropper with your eye or other body surface to avoid contamination.
Apply applying AZARGA EYE DROPS, leave a time gap of at least 5 minutes before applying other eye drops or ointment. If you wear soft contact lenses, remove the lens before applying AZARGA EYE DROPS and wait for at least 15 minutes before reinsertion.
Your doctor will decide the correct dose and duration of therapy for you depending upon the severity of the disease condition. Do not stop using AZARGA EYE DROPS without consulting your doctor, as the pressure within the eye may raise once again.
Stop using AZARGA EYE DROPS and contact your immediately if you experience any of the following side effects:
Burning or stinging of eyes:
Wash your eyes with plain cold water. Place an ice pack on your eye to ease the irritation. Avoid straining your eyes by looking at mobile phones, laptops or television. Wear protective eyeglasses while going outdoors.
Blurred vision:
Close your eyes and relax. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
AZARGA EYE DROPS is generally not recommended for use in pregnant women. Therefore, consult your doctor for advice before using it.
AZARGA EYE DROPS is generally not recommended for use in breastfeeding women. Therefore, consult your doctor for advice before using it.
Do not drive or operate any heavy tools or machines if you experience dizziness or blurred vision after using AZARGA EYE DROPS.
AZARGA EYE DROPS is not recommended for use in patients with severe kidney diseases. It should be used with caution in patients with other minor kidney problems. Therefore, consult your doctor before using it.
AZARGA EYE DROPS should be used with caution in patients with liver problems. Therefore, consult your doctor before using it.
Do not use AZARGA EYE DROPS if you are allergic to Brinzolamide, Timolol, sulphonamides (such as glipizide, gliclazide), diuretics (such as furosemide) or to any other beta-blockers (Ex. labetalol).
AZARGA EYE DROPS is not recommended for use in patients who currently have or previously had any lung problems such as asthma or COPD. It should be used with caution in patients with breathing difficulties. Therefore, consult your doctor before using it.
AZARGA EYE DROPS is not recommended for use in patients with heart problems (such as slow or irregular heartbeat or heart failure). It should be used with caution in patients with coronary artery disease. Therefore, consult your doctor before using it.
AZARGA EYE DROPS is not recommended for use if you:
Before using AZARGA EYE DROPS, inform your doctor if you:
Use in pediatrics:
AZARGA EYE DROPS should be used with caution in children and adolescents (aged below 18 years). Therefore, consult your doctor before using it.
Use in geriatrics:
AZARGA EYE DROPS should be used with caution in elderly patients. Therefore, consult your doctor before using it.
A. Drug-Drug interactions:
Before using AZARGA EYE DROPS, inform your doctor if you are taking any of the following medicines such as:
Overdosage:
If you or anyone else accidentally used more AZARGA EYE DROPS, rinse your eye with warm water. If still irritation persists, consult your doctor. If you or anyone else accidentally swallowed this medicine, contact your doctor or visit the nearby hospital. Symptoms of overdosage might include headache, dizziness, difficulty in breathing, slow heart rate and chest pain.
Drug | : | Brinzolamide, Timolol |
Pharmacological Category | : | Carbonic anhydrase inhibitors, Beta-blockers |
Therapeutic Indication | : | Glaucoma, Ocular hypertension |
Dosage Forms | : | Eye drops |
Can the use of AZARGA EYE DROPS cause blurred vision?
Yes. AZARGA EYE DROPS may cause blurred vision after application. If your vision becomes blur, close your eyes for some time and rest. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
Can I use other eye medicines while using AZARGA EYE DROPS?
Yes. You can use other eye medicines while undergoing therapy with AZARGA EYE DROPS. But make sure to leave a time gap of at least 5 minutes before applying other eye drops or ointment.
Who should avoid using AZARGA EYE DROPS?
AZARGA EYE DROPS should be avoided in patients with severe kidney or heart problems. It should be used with caution in patients with liver problems, low blood pressure, diabetes, thyroid problems and problems in blood circulation. It is also not suitable for use in pregnant or breastfeeding women. Patients aged below 18 years must consult your doctor before using AZARGA EYE DROPS.
How to use AZARGA EYE DROPS?
Use AZARGA EYE DROPS as advised by your physician. It is for ophthalmic use only. Instil few drops of the medicine into the affected eye(s). Close your eyes and press the corner of your eye with your finger for a minute. If you wear soft contact lenses, remove the lens before applying AZARGA EYE DROPS and wait for at least 15 minutes before reinsertion.
What is the use of AZARGA EYE DROPS?
AZARGA EYE DROPS is a prescription medicine used to treat increased pressure within the eyes. It is typically used in patients who have not responded adequately to therapy with beta-blockers (Ex. timolol) alone.
How long does it take for [GBNKRYWORD] to work?
It may take about 1 to 4 weeks for AZARGA EYE DROPS to show the results. Therefore, continue to use AZARGA EYE DROPS as prescribed by your physician.
What are the side effects of AZARGA EYE DROPS?
The most common side effects of using AZARGA EYE DROPS are burning or stinging of eyes, eye redness and itching, blurred vision and bitter taste. Consult your doctor if any of these side effect bothers you.
Can I use AZARGA EYE DROPS while wearing contact lenses?
If you wear soft contact lenses, remove the lens before applying AZARGA EYE DROPS and wait for at least 15 minutes before reinsertion. This is because AZARGA EYE DROPS contains preservatives which may interact with your contact lens and make your lens to discolour.
Can I stop using AZARGA EYE DROPS without consulting my doctor?
Do not stop using AZARGA EYE DROPS without consulting your doctor, as the pressure within the eye may raise once again. If you think that you are feeling better or if you wish to stop using AZARGA EYE DROPS, contact your doctor for advice. Your doctor will check your condition and gradually withdraw the dose.
Is AZARGA EYE DROPS safe for pregnant and breastfeeding women?
AZARGA EYE DROPS is generally not recommended for use in pregnant women or breastfeeding women. Therefore, consult your doctor before using it.
Can I drive or ride a bike after using AZARGA EYE DROPS?
Do not drive if you feel dizzy or experience blurred vision after using AZARGA EYE DROPS. It also effects the ability to perform tasks that need alertness or coordination, and so be cautious while driving.
What if I miss a dose of AZARGA EYE DROPS?
If you missed a dose of AZARGA EYE DROPS, apply it as soon as you remember. However, if it is time for next dose, skip the missed dose and apply the regular dose. Do not apply a double dose to compensate the missed dose.
1. KD. Tripathi. Antiadrenergic drugs and Drugs for Glaucoma. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 148 & 153.
2. Robert F. Reilly and Edwin K. Jackson. Regulation of Renal volume and vascular volume. Goodman and Gilman’s The Pharmacological Basis of Therapeutics. 12th Edition. Page – 680.
3. Keiji Yoshikawa, Jun Kozaki, and Hidetaka Maeda. Efficacy and safety of brinzolamide/timolol fixed combination compared with timolol in Japanese patients with open-angle glaucoma or ocular hypertension. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. February 2014. [Accessed on 12th December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926459/
4. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in December 2019]. [Accessed on 12th December 2022] https://www.medicines.org.uk/emc/files/pil.11573.pdf
5. Brio-T Eye drops. Sunways Private Ltd. [Accessed on 12th December 2022] http://www.sunways.com/Products/SunwaysProducts/Brio-T.html
6. Central Drugs Standard Control Organization (CDSCO). Brinzolamide USP…………1.0% w/v Timolol Maleate IP……......0.683%w/v eq. to Timolol………………0.5%w/v Benzalkonium Chloride IP (As preservative) ………………0.01% w/v Ophthalmic Suspension. February 2016. [Accessed on 12th December 2022] https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/dciApprovedfdc.pdf
Written By Srilekha. R, B.Pharm
Last updated on 12 Dec 2022 | 06:06 PM(IST)