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INTRODUCTION AZOPT OPHTHALMIC SUSPENSION contains Brinzolamide which belongs to the group of medicines called Ophthamic anti-glaucoma agents. It is used to treat glaucoma. Glaucoma is group of eye condition that damages the optic nerve (nerves which are responsible for proper vision). It is ch...
AZOPT OPHTHALMIC SUSPENSION contains Brinzolamide which belongs to the group of medicines called Ophthamic anti-glaucoma agents. It is used to treat glaucoma. Glaucoma is group of eye condition that damages the optic nerve (nerves which are responsible for proper vision). It is characterized by increased pressure within the eyes caused due to impaired secretion or drainage of fluids (aqueous humour) within the eyes. During the intial days, glaucoma may remain asymptomatic. At later stages, it may cause eye pain or redness, halos around the light, severe headache or blurred vision.
Brinzolamide reduces pressure within the eye. It works by blocking the action of an enzyme called carbonic anhydrase, that causes pressure within the eye to raise. As a result, it decreases the elevated pressure within the eye and provides relief from unpleasant symptoms (such as eye pain, headache, or blurred vision).
AZOPT OPHTHALMIC SUSPENSION is not recommended for use in patients with kidney problems. It should be used with caution in patients with liver problems, dry eyes, or corneal problems. AZOPT OPHTHALMIC SUSPENSION is generally not recommended for use in pregnant and in breastfeeding women unless considered necessary by the physician. It is also not suitable for use in children and adolescents.
If you wear soft contact lenses, remove the lens before applying AZOPT OPHTHALMIC SUSPENSION and wait for at least 15 minutes before reinsertion. Do not stop using AZOPT OPHTHALMIC SUSPENSION without consulting your doctor, because premature discontinuation can further increase the pressure within the eye. The most common side effects of AZOPT OPHTHALMIC SUSPENSION are eye irritation, blurred vision, and bitter taste in mouth. Consult your doctor if any of the side effect bothers you.
AZOPT OPHTHALMIC SUSPENSION effectively reduces pressure within the eye where brinzolamide acts by blocking the action of an enzyme called carbonic anhydrase, which is responsible for increasing the production of aqueous humour (fluid in the eyes) and subsequent increase in the intraocular pressure (pressure within the eye). Blockade of carbonic anhydrase decreases the production of aqueous humour and reduces the elevated pressure within the eye which therefore provides relief from unpleasant symptoms (such as eye pain, headache or blurred vision).
Use AZOPT OPHTHALMIC SUSPENSION as advised by your physician. It is for ophthalmic use only. Do not swallow. Wash your hands before and after application. Tilt your head slightly and gently pull the lower eyelid downwards. Instil few drops of the medicine into the affected eye(s). Close your eyes and press the corner of your eye with your finger for a minute. Do not touch the tip of the dropper with your eye or other body surface to avoid contamination.
Apply applying AZOPT OPHTHALMIC SUSPENSION, leave a time gap of at least 5 minutes before applying other eye drops or ointment. If you wear soft contact lenses, remove the lens before applying AZOPT OPHTHALMIC SUSPENSION and wait for at least 15 minutes before reinsertion.
Your doctor will decide the correct dose and duration of therapy for you depending upon the severity of the disease condition. Do not stop using AZOPT OPHTHALMIC SUSPENSION without consulting your doctor, as the pressure within the eye may raise once again and become uncontrollable.
Stop using AZOPT OPHTHALMIC SUSPENSION and contact your immediately if you experience any of the following side effects:
Wash your eyes with plain cold water. Place an ice pack on your eye to ease the irritation. Avoid straining your eyes by looking at mobile phones, laptops, or television. Wear protective eyeglasses while going outdoors.
Close your eyes and relax. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
AZOPT OPHTHALMIC SUSPENSION is generally not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before using. Women of childbearing age should use proper contraceptive method to avoid pregnancy while undergoing therapy with AZOPT OPHTHALMIC SUSPENSION.
AZOPT OPHTHALMIC SUSPENSION is generally not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before using.
Do not drive or operate any heavy tools or machines if you experience dizziness or blurred vision after using AZOPT OPHTHALMIC SUSPENSION.
AZOPT OPHTHALMIC SUSPENSION is not recommended for patients with severe kidney diseases. It should be used with caution in patients with other minor kidney problems. Therefore, consult your doctor before using.
AZOPT OPHTHALMIC SUSPENSION should be used with caution in patients with liver problems. Therefore, consult your doctor before using.
Do not use AZOPT OPHTHALMIC SUSPENSION if you are allergic to Brinzolamide.
AZOPT OPHTHALMIC SUSPENSION is generally not recommended for use in children and adolescents (below 18 years). Therefore, consult your doctor before using.
[GBNKEYWORD[ should be used with caution in elderly patients. Therefore, consult your doctor before using.
AZOPT OPHTHALMIC SUSPENSION is not recommended for use if you:
Before using AZOPT OPHTHALMIC SUSPENSION, inform your doctor if you:
A. Drug-Drug interactions:
Before using AZOPT OPHTHALMIC SUSPENSION, inform your doctor if you are taking any of the following medicines such as:
Overdosage:
If you or anyone else accidentally used more AZOPT OPHTHALMIC SUSPENSION, rinse your eye with warm water. If still irritation persists, consult your doctor.
| Drug | : | Brinzolamide |
| Pharmacological Category | : | Carbonic anhydrase inhibitors |
| Therapeutic Indication | : | Glaucoma |
| Dosage Forms | : | Eye drops, Ophthalmic suspension |
Q: Can the use of AZOPT OPHTHALMIC SUSPENSION cause blurred vision?
A: Yes. AZOPT OPHTHALMIC SUSPENSION may cause blurred vision after application. If your vision becomes blur, close your eyes for some time and rest. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
Q: Is it normal to experience headache after using AZOPT OPHTHALMIC SUSPENSION?
A: Yes. The use of AZOPT OPHTHALMIC SUSPENSION can cause headache in some indivduals. It is one of the uncommon side effects of AZOPT OPHTHALMIC SUSPENSION. It happens when too much of the medicines enters your blood. If you experience headache, rest and relax. Applying a pain-relieving balm on your forehead can be beneficial. Do not stress yourself too much. Avoid consuming excessive alcohol. Consult your doctor if your headache worsens.
Q: Can I use other eye medicines while using AZOPT OPHTHALMIC SUSPENSION?
A: Yes. You can use other eye medicines while undergoing therapy with AZOPT OPHTHALMIC SUSPENSION. But make sure to leave a time gap of at least 5 minutes before applying other eye drops or ointment.
Q: Who should avoid using AZOPT OPHTHALMIC SUSPENSION?
A: AZOPT OPHTHALMIC SUSPENSION should be avoided in patients with severe kidney problems. It should be used with caution in patients with liver problems or other problems in eye such as eye dryness, corneal problems or narrow-angle glaucoma. It is also not suitable for use in patients having too much acidity in blood (hyperchloremic acidosis). Patients aged below 18 years must consult your doctor before using AZOPT OPHTHALMIC SUSPENSION.
Q: How to use AZOPT OPHTHALMIC SUSPENSION?
A: Use AZOPT OPHTHALMIC SUSPENSION as advised by your physician. It is for ophthalmic use only. Instil few drops of the medicine into the affected eye(s). Close your eyes and press the corner of your eye with your finger for a minute. If you wear soft contact lenses, remove the lens before applying AZOPT OPHTHALMIC SUSPENSION and wait for at least 15 minutes before reinsertion. Do not stop using AZOPT OPHTHALMIC SUSPENSION without consulting your doctor, as the pressure within the eye may raise once again and become uncontrollable.
Q: What is the use of AZOPT OPHTHALMIC SUSPENSION?
A: AZOPT OPHTHALMIC SUSPENSION is a prescription medicine used to treat glaucoma in adult patients. It effectively reduces pressure within the eye by blocking the action of an enzyme called carbonic anhydrase, that causes pressure within the eye to raise.
Q: How long does it take for [GBNKRYWORD] to work?
A: It may take about 1 to 4 weeks for AZOPT OPHTHALMIC SUSPENSION to show the results. Therefore, continue to use AZOPT OPHTHALMIC SUSPENSION as prescribed by your physician.
Q: Is AZOPT OPHTHALMIC SUSPENSION same as timolol?
A: No. AZOPT OPHTHALMIC SUSPENSION contains Brinzolamide which is a carbonic anhydrase inhibitor. It acts by blocking the action of an enzyme called carbonic anhydrase, that causes pressure within the eye to raise. Whereas timolol is a beta-blocker which acts by reducing intraocular pressure by blocking the beta-receptors of the eye. Although both are used to treat glaucoma, they are not the same.
Q: What are the side effects of AZOPT OPHTHALMIC SUSPENSION?
A: The most common side effects of AZOPT OPHTHALMIC SUSPENSION are eye irritation, blurred vision, and bitter taste in mouth. Sometimes people may also experience systemic side effects like headache, dizziness, fast heart rate or shortness of breath. Consult your doctor if any of the side effect bothers you.
Q: Can I use AZOPT OPHTHALMIC SUSPENSION while wearing contact lenses?
A: If you wear soft contact lenses, remove the lens before applying AZOPT OPHTHALMIC SUSPENSION and wait for at least 15 minutes before reinsertion. This is because AZOPT OPHTHALMIC SUSPENSION contains benzalkonium chloride which may interact with your contact lens and make your lens to discolour.
Q: Can I stop using AZOPT OPHTHALMIC SUSPENSION without consulting my doctor?
A: Do not stop using AZOPT OPHTHALMIC SUSPENSION without consulting your doctor, as the pressure within the eye may raise once again and become uncontrollable. If you think that you are feeling better or if you wish to stop using AZOPT OPHTHALMIC SUSPENSION, contact your doctor for advice. Your doctor will check your condition and gradually withdraw the dose.
Q: Is AZOPT OPHTHALMIC SUSPENSION safe for pregnant and breastfeeding women?
A: AZOPT OPHTHALMIC SUSPENSION is generally not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before using. Women of childbearing age should use proper contraceptive method to avoid pregnancy while undergoing therapy with AZOPT OPHTHALMIC SUSPENSION.
Q: Can I drive or ride a bike after using AZOPT OPHTHALMIC SUSPENSION?
A: Do not drive if you feel dizzy or experience blurred vision after using AZOPT OPHTHALMIC SUSPENSION. It also effects the ability to perform tasks that need alertness or coordination so be cautious while driving.
Q: What if I miss a dose of AZOPT OPHTHALMIC SUSPENSION?
A: If you missed a dose of AZOPT OPHTHALMIC SUSPENSION, apply it as soon as you remember. However, if it is time for next dose, skip the missed dose and use the regular dose. Do not use a double dose to compensate the missed dose.
Q: Is AZOPT OPHTHALMIC SUSPENSION and brimonidine same?
A: No. AZOPT OPHTHALMIC SUSPENSION contains Brinzolamide which is a carbonic anhydrase inhibitor. It acts by blocking the action of an enzyme called carbonic anhydrase, that causes pressure within the eye to raise. Whereas brimonidine is an alpha-agonist used to treat narrow-angle glaucoma. It works by activating the alpha receptors of the eye. Although both are used to treat glaucoma, they are not the same.
1. Robert F. Reilly and Edwin K. Jackson. Regulation of Renal volume and vascular volume. Goodman and Gilman’s The Pharmacological Basis of Therapeutics. 12th Edition. Page – 680.
2. Michele Iester. Brinzolamide ophthalmic suspension: a review of its pharmacology and use in the treatment of open angle glaucoma and ocular hypertension. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. September 2008. [Accessed on 11th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694021/
3. Accord. Electronic Medicines Compendium (EMC). [Revised in September 2020] [Accessed on 9th May 2022] https://www.medicines.org.uk/emc/files/pil.7281.pdf
4. Novartis Pharma. Electronic Medicines Compendium (EMC). [Accessed on 9th May 2022] https://www.ema.europa.eu/en/documents/product-information/azopt-epar-product-information_en.pdf
5. Mylan. Electronic Medicines Compendium (EMC). [Revised in December 2018] [Accessed on 9th May 2022] https://www.medicines.org.uk/emc/files/pil.688.pdf
Written By Srilekha. R, B.Pharm
Last updated on 10 Mar 2023 | 12:47 PM(IST)