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INTRODUCTION ALPHAGAN contains Brimonidine which belongs to the group of medicines called Ophthalmic anti-glaucoma agents. It is used to treat ocular hypertension and glaucoma. Ocular hypertension refers to increased pressure within the eye without any significant damage to the optic nerve. Wh...
ALPHAGAN contains Brimonidine which belongs to the group of medicines called Ophthalmic anti-glaucoma agents. It is used to treat ocular hypertension and glaucoma. Ocular hypertension refers to increased pressure within the eye without any significant damage to the optic nerve. Whereas glaucoma is a group of eye condition that causes significant damage to the optic nerve due to elevated pressure within the eye followed by vision loss if left untreated.
Both ocular hypertension and glaucoma are caused due to impaired secretion or drainage of fluids (aqueous humour) within the eyes. Brimonidine reduces the pressure within the eyes by decreasing the production of excessive eye fluids (aqueous humour) while simultaneously increasing their drainage. This reduces strain on the eyes and therefore decreases the elevated pressure within the eye.
Before using ALPHAGAN inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you have depression or other types of mental illnesses.
Consult your doctor before using ALPHAGAN if you are pregnant or think you may be pregnant or breastfeeding. It is not recommended for use in children aged below 12 years due to lack of safety data.
If you wear soft contact lenses, remove the lens before applying ALPHAGAN and wait for at least 15 minutes before reinsertion. ALPHAGAN may make your vision blur, therefore be cautious while you drive or operate heavy tools.
The most common side-effect of using ALPHAGAN are eye redness, burning sensation, eye inflammation and itching, watery eyes, dry mouth, and blurred vision. Consult your doctor if any of these side effect worsens.
ALPHAGAN effectively reduces the elevated pressure within the eye, where brimonidine acts by decreasing the production of excessive eye fluids (aqueous humour) while simultaneously increasing their drainage. This reduces strain on the eyes and therefore decreases the elevated pressure within the eye.
Use ALPHAGAN as advised by your doctor. It is for ophthalmic use only. Wash your hands before use. Instil few drops of ALPHAGAN into the affected eye. Close your eyes and press the corner of your eye with your finger for a minute.
Do not touch the tip of the dropper with your eye or other body surface to avoid contamination. Apply applying ALPHAGAN, leave a time gap of at least 5 minutes before applying other eye drops or ointment. If you wear soft contact lenses, remove the lens before applying ALPHAGAN and wait for at least 15 minutes before reinsertion.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop using ALPHAGAN without consulting your doctor, as the pressure within the eye may raise once again.
Stop using ALPHAGAN and contact your doctor immediately if you experience any of the following symptoms:
Eye redness, itching or burning sensation:
Wash your eyes with plain cold water. Place an ice pack on your eye to ease the irritation. Avoid straining your eyes by looking at mobile phones, laptops, or television. Wear protective eyeglasses while going outdoors.
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Blurred vision:
Close your eyes and relax. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
ALPHAGAN should be used with caution in pregnant women. Therefore, consult your doctor before using it.
ALPHAGAN is not recommended for use in breastfeeding women. Therefore, consult your doctor before using it.
Do not drive or operate any heavy tools or machines if you experience blurred vision, drowsiness or tiredness after using ALPHAGAN.
Avoid the consumption of alcohol while using ALPHAGAN as it may increase the risk of side effects.
ALPHAGAN should be used with caution in patients having kidney diseases.Therefore, consult your doctor before using it.
ALPHAGAN should be used with caution in patients having liver diseases.Therefore, consult your doctor before using it.
Do not use ALPHAGAN if you are allergic to Brimonidine.
ALPHAGAN should be used with caution in patients with heart diseases.Therefore, consult your doctor before using it.
Before using ALPHAGAN, inform your doctor if you:
Use in pediatrics:
ALPHAGAN can be used in children and adolescents aged between 2-12 years if prescribed by a physician. It is not recommended for use in infants and children aged below 12 years due to lack of safety data. Therefore, consult your doctor before using it.
Use in geriatrics:
ALPHAGAN should be used with caution in elderly patients. Therefore, consult your doctor before using it.
A. Drug-Drug Interaction:
Before using ALPHAGAN, inform your doctor if you are taking any of the following:
Overdosage:
It is unlikely to have an overdosage of ALPHAGAN in adults. However, if overdosage occurs in children receiving ALPHAGAN as a part of their treatment contact your doctor immediately. Symptoms of overdosage might include sleepiness, floppiness, low temperature or breathing difficulties.
| Drug | : | Brimonidine |
| Pharmacological Category | : | Alpha adrenergic receptor agonists |
| Therapeutic Indication | : | Glaucoma |
| Dosage Forms | : |
Eye Drops, Ophthalmic Solution, Gel |
Are there any specific instructions I need to follow while using ALPHAGAN?
ALPHAGAN is only meant for ophthalmic use only. Do not touch the tip of the dropper with your eye or other body surface to avoid contamination. Apply applying ALPHAGAN, leave a time gap of at least 5 minutes before applying other eye drops or ointment. If you wear soft contact lenses, remove the lens before applying ALPHAGAN and wait for at least 15 minutes before reinsertion.
What if I miss a dose of ALPHAGAN?
If you missed a dose of ALPHAGAN, apply it as soon as you remember. However, if it is time for next dose, skip the missed dose and use the regular dose. Do not use a double dose of ALPHAGAN to compensate the missed dose.
Can ALPHAGAN cause blurred vision?
Yes. ALPHAGAN may cause blurred vision after application. If you experience blurred vision, close your eyes and relax. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if your condition did not improve.
What is the use of ALPHAGAN ?
ALPHAGAN is used to treat ocular hypertension and glaucoma. It decreases the elevated pressure within the eye and reduces the risk of optic nerve damage and subsequent vision loss.
What type of drug is [ GBNKEYWORD] ?
ALPHAGAN contains Brimonidine which is an alpha-adrenergic receptor agonist. treat ocular hypertension and glaucoma. It decreases the elevated pressure within the eye and reduces the risk of optic nerve damage and subsequent vision loss.
Who should not take [ GBNKEYWORD] ?
Do not take ALPHAGAN if you are allergic to brimonidine. Inform your doctor if you are pregnant or breastfeeding before using ALPHAGAN. It is not suitable for use in children aged below 12 years. Patients taking antidepressants must consult their doctor before taking ALPHAGAN.
How long do you take ALPHAGAN ?
Take ALPHAGAN as advised by your doctor. ALPHAGAN is usually taken as long-term therapy along with other medicines to treat glaucoma. Therefore, take it as long as prescribed by your doctor. Do not stop taking ALPHAGAN without consulting your doctor.
Can I stop using ALPHAGAN without consulting my doctor?
Do not stop using ALPHAGAN without consulting your doctor. If you think that you are feeling better or if you wish to stop using ALPHAGAN, contact your doctor for advice. Your doctor will check your condition and gradually withdraw the use of ALPHAGAN.
Can I use other eye medicines while using ALPHAGAN?
Yes. You can use other eye medicines while undergoing therapy with ALPHAGAN. But make sure to leave a time gap of at least 5 minutes before applying other eye drops or ointment.
Can I use ALPHAGAN while wearing contact lenses?
If you wear soft contact lenses, remove the lens before applying ALPHAGAN and wait for at least 15 minutes before reinsertion.
Is [ GBNKEYWORD] a beta blocker?
No. ALPHAGAN is not a beta blocker. ALPHAGAN contains Brimonidine which belongs to the group of medicines called Alpha adrenergic receptor agonists. It is used to treat ocular hypertension and glaucoma.
Can we drink alcohol while using [ GBNKEYWORD] ?
No, you should not drink alcohol while using ALPHAGAN as it may increase the risk of side effects.
1. KD. Tripathi. Anti-Adrenergic Drugs Acting on ANS. Essentials of medical pharmacology. Seventh edition. 2013. Page – 154.
2. Louis B Cantor. Brimonidine in the treatment of glaucoma and ocular hypertension. NIH. National Library of Medicine, National center for biotechnology information. Pubmed central. December 2006. [Accessed on 14th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1936355/
3. FDC International Ltd. Electronic Medicines Compendium (EMC). [Revised in October 2020]. [Accessed on 13th May 2022] https://www.medicines.org.uk/emc/files/pil.3426.pdf
4. Allergan, Inc. US Food and Drug Administration (USFDA). [Revised in May 2010]. [Accessed on 13th May 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021262s020,021770s004lbl.pdf
5. Allergan New Zealand Ltd. [Revised in Feb 2013]. [Accessed on 13th May 2022] https://allergan-web-cdn-prod.azureedge.net/allergan/allergannewzealand/media/allergannewzealand/products/alphagan-p-nz-ds.pdf