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INTRODUCTION DOMSTAL 10MG TABLET contains Domperidone which belongs to the group of medicines called Dopamine antagonists. It is used in the prevention of nausea and vomiting associated with central or local origin, chemotherapy or radiotherapy, drugs or migraine. Nausea a...
DOMSTAL 10MG TABLET contains Domperidone which belongs to the group of medicines called Dopamine antagonists. It is used in the prevention of nausea and vomiting associated with central or local origin, chemotherapy or radiotherapy, drugs or migraine.
Nausea and vomiting are not a disease but symptoms of different conditions such as infections, food poisoning, motion sickness, overeating, blocked intestine, migraine, indigestion and many more.
DOMSTAL 10MG TABLET can also be used for relief of postprandial symptoms of fullness, nausea, epigastric bloating and belching (burping) that is occasionally accompanied by stomach discomfort and heartburn.
DOMSTAL 10MG TABLET is not recommended for use in patients having heart or moderate to severe liver diseases, bleeding in the stomach or intestines, blockage or tear in your intestines, and tumors in the pituitary gland (prolactinoma). DOMSTAL 10MG TABLET should be used with caution in patients having kidney diseases.
DOMSTAL 10MG TABLET should be used with caution in pregnant women and should be used in breastfeeding women only if considered clearly necessary by the doctor. Ask for your doctor’s advice before taking it. DOMSTAL 10MG TABLET should be used with caution in elderly patients (above 60 years of age).
DOMSTAL 10MG TABLET should not be used in children below 12 years or weighing less than 35kgs. Consult with your child’s doctor. The common side effect of taking DOMSTAL 10MG TABLET includes a dry mouth. Consult with your doctor if this worsens or doesn’t improve.
Prevents nausea and vomiting associated with:
Relieves:
DOMSTAL 10MG TABLET is has an anti-emetic property which acts by blocking a chemical messenger in the brain called dopamine, that transfers information through nerve endings. DOMSTAL 10MG TABLET functions by inhibiting the muscle contraction that occurs naturally in the digestive system and enhances the peristaltic movement in the food pipe which helps in facilitating the digestion time faster, this causes calming down effect, thereby relieving nausea or vomiting sensation.
Take DOMSTAL 10MG TABLET as advised by your physician. It can be taken before meals.
For Tablet, Capsule: Swallow DOMSTAL 10MG TABLET with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse DOMSTAL 10MG TABLET in the specified quantity of water as mentioned on the label. Consume the mixture immediately after reconstitution.
Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight and disease condition. Continue to take DOMSTAL 10MG TABLET for the stipulated duration prescribed by your doctor to achieve better results.
Stop taking DOMSTAL 10MG TABLET and consult your doctor immediately if you experience any of the following side effects
Dry mouth:
Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your physician for advice.
diarrhoea:
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Ask for your doctor’s advice if diarrhoea doesn’t improve.
Headache:
Try to take rest and don’t involve yourself in exertive activities. Rest in a quiet and dark room. Apply a pain-relieving balm on your forehead. Ask for your doctor’s advice if the headache doesn’t improve
Drowsiness:
Take adequate sleep. Do not involve in rigorous activities. Do not interfere with your sleep cycle. Talk to your doctor if the drowsiness doesn’t improve.
Itchy skin:
Hot water makes your skin irritated, so avoid taking hot showers. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. To soothe and hydrate the irritated skin, apply moisturizers. Contact your doctor if the itching worsens.
DOMSTAL 10MG TABLET should be used with caution in pregnant women. Consult your doctor before taking it.
DOMSTAL 10MG TABLET is not recommended for use in breastfeeding women as it may pass through breast milk. DOMSTAL 10MG TABLET may cause unwanted side effects affecting the heart in a breastfed baby. It should only be used only if considered clearly necessary by the doctor. Consult your doctor before taking DOMSTAL 10MG TABLET.
DOMSTAL 10MG TABLET does not affect the ability to drive or use machines. Yet do not drive or operate any machines if you feel dizzy after taking DOMSTAL 10MG TABLET.
DOMSTAL 10MG TABLET should be taken with caution in patients with kidney problems such as kidney impairment or kidney failure. Your doctor might consider adjusting your dose. Consult your doctor before taking it.
Do not take DOMSTAL 10MG TABLET if you are allergic to domperidone or any other ingredients present in it.
DOMSTAL 10MG TABLET is not recommended in patients suffering from heart problems such as prolonged QT corrected interval (reading in eco cardiogram (ECG) machine) or heart failure (heart cannot pump blood properly). Kindly consult a doctor before taking DOMSTAL 10MG TABLET.
DOMSTAL 10MG TABLET is not recommended for use if you:
Use in pediatrics:
DOMSTAL 10MG TABLET is not recommended for use in children below 12 years of age or weighing less than 35 kgs. Consult with your child’s doctor before giving DOMSTAL 10MG TABLET to your child.
Use in geriatrics:
DOMSTAL 10MG TABLET should be used with caution for use over 60 years of age, as DOMSTAL 10MG TABLET be associated with an increased risk of heart rhythm disorder and cardiac arrest. Consult your doctor before taking it.
A. Drug-Drug interactions:
Before taking DOMSTAL 10MG TABLET, inform your doctor if you are taking any of the following medicines:
Overdosage:
If you or anyone else accidentally took too much of DOMSTAL 10MG TABLET, consult your doctor immediately. The symptoms might include feeling sleepy, confused, uncontrolled movements of the eye and tongue and abnormal posture (like a twisted neck).
| Drug | : | Domperidone |
| Pharmacological Category | : | Dopamine antagonists |
| Therapeutic Indication | : | Nausea and Vomiting |
| Dosage Forms | : |
Tablets, Capsules, Dispersible tablets, Rapitab, Suspension, Oral Suspension, Syrup, Oral Drops, Drops |
What is DOMSTAL 10MG TABLET and why is it prescribed?
DOMSTAL 10MG TABLET contains Domperidone which belongs to the group of medicines called Dopamine antagonists. It is used in the prevention of nausea and vomiting associated with central or local origin, chemotherapy or radiotherapy, drugs or migraine. DOMSTAL 10MG TABLET can also be used in relief of postprandial symptoms of fullness, nausea, epigastric bloating and belching (burping) that is occasionally accompanied by stomach discomfort and heartburn.
How long can I take DOMSTAL 10MG TABLET?
It is recommended that DOMSTAL 10MG TABLET be taken for the shortest period and at the lowest dose. This is because DOMSTAL 10MG TABLET can cause an irregular heartbeat when taken for a longer period or at a high dose. Ask for your doctor’s advice.
Can I take DOMSTAL 10MG TABLET with antibiotics?
Use of DOMSTAL 10MG TABLET with antibiotics like erythromycin, levofloxacin, and some antifungals is not recommended as this can cause interaction. Please consult your doctor for advice before using any antibiotics with DOMSTAL 10MG TABLET.
Does DOMSTAL 10MG TABLET increase milk secretion?
Yes, DOMSTAL 10MG TABLET can increase milk secretion also known as galactorrhoea. This is an uncommon side effect of using DOMSTAL 10MG TABLET. Talk to your doctor if you are experiencing this side effect while taking this medicine.
Does DOMSTAL 10MG TABLET cause heart problems?
DOMSTAL 10MG TABLET may be associated with an increased risk of heart problems (like an irregular heartbeat) and heart attacks. The risk also increases when DOMSTAL 10MG TABLET is given together with other medicines. Inform the doctor of your medication history when taking DOMSTAL 10MG TABLET.
Does DOMSTAL 10MG TABLET cause dry mouth?
Yes, DOMSTAL 10MG TABLET can cause dry mouth. A dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your physician for advice.
What is the best time to take DOMSTAL 10MG TABLET?
It is recommended to take DOMSTAL 10MG TABLET before meals. If taken after meals, absorption of the medicine is somewhat delayed. Patients should try to take each dose of DOMSTAL 10MG TABLET at a scheduled time to avoid missing a dose.
What is DOMSTAL 10MG TABLET and why is it prescribed?
DOMSTAL 10MG TABLET contains Domperidone which belongs to the group of medicines called Dopamine antagonists. It is used in the prevention of nausea and vomiting associated with central or local origin, chemotherapy or radiotherapy, drugs or migraine. DOMSTAL 10MG TABLET can also be used in relief of postprandial symptoms of fullness, nausea, epigastric bloating and belching (burping) that is occasionally accompanied by stomach discomfort and heartburn.
How long can I take DOMSTAL 10MG TABLET?
It is recommended that DOMSTAL 10MG TABLET be taken for the shortest period and at the lowest dose. This is because DOMSTAL 10MG TABLET can cause an irregular heartbeat when taken for a longer period or at a high dose. Ask for your doctor’s advice.
Can I take DOMSTAL 10MG TABLET with antibiotics?
Use of DOMSTAL 10MG TABLET with antibiotics like erythromycin, levofloxacin, and some antifungals is not recommended as this can cause interaction. Please consult your doctor for advice before using any antibiotics with DOMSTAL 10MG TABLET.
Does DOMSTAL 10MG TABLET increase milk secretion?
Yes, DOMSTAL 10MG TABLET can increase milk secretion also known as galactorrhoea. This is an uncommon side effect of using DOMSTAL 10MG TABLET. Talk to your doctor if you are experiencing this side effect while taking this medicine.
Does DOMSTAL 10MG TABLET cause heart problems?
DOMSTAL 10MG TABLET may be associated with an increased risk of heart problems (like an irregular heartbeat) and heart attacks. The risk also increases when DOMSTAL 10MG TABLET is given together with other medicines. Inform the doctor of your medication history when taking DOMSTAL 10MG TABLET.
Does DOMSTAL 10MG TABLET cause dry mouth?
Yes, DOMSTAL 10MG TABLET can cause dry mouth. A dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your physician for advice.
What is the best time to take DOMSTAL 10MG TABLET?
It is recommended to take DOMSTAL 10MG TABLET before meals. If taken after meals, absorption of the medicine is somewhat delayed. Patients should try to take each dose of DOMSTAL 10MG TABLET at a scheduled time to avoid missing a dose.
REFERENCES
1. KD Tripathi. Antiemetics. Essentials of Medical Pharmacology. Eighth edition. 2019. Page - 414.
2. Rhew K, Han N, Oh JM. Impact of Safety Warning on Domperidone Prescribing for Geriatric Patients in South Korea: Analysis of National Insurance Claim Data. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubmed Central. August 2019. [Accessed on 3rd November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719182/
3. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubchem. Domperidone. [Accessed on 3rd November 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Domperidone
4. Savio C Reddymasu, Irfan Soykan, Richard W McCallum. Domperidone: review of pharmacology and clinical applications in gastroenterology. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubmed.gov. September 2007. [Accessed on 3rd November 2022] https://pubmed.ncbi.nlm.nih.gov/17488253/
5. S.C. Zentiva S.A. Electronic Medicines Compendium (emc). [Revised in April 2021] [Accessed on 3rd November 2022] https://www.medicines.org.uk/emc/files/pil.4177.pdf
6. Torrent Pharmaceuticals Ltd. Domstal DT (Domperidone). [Revised in February 2022]. [Accessed on 3rd November 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/3082.pdf
7. Torrent Pharmaceuticals Ltd. Domstal (Domperidone). [Revised in April 2022]. [Accessed on 3rd November 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1623.pdf
8. Torrent Pharmaceuticals Ltd. Domstal OD (Domperidone). [Accessed on 3rd November 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/408.pdf
9. Janssen-Cilag (New Zealand) Ltd. Medsafe. [Revised in November 2020]. [Accessed on 3rd November 2022] https://www.medsafe.govt.nz/profs/Datasheet/m/motiliumtab.pdf
10. Morepen Laboratories Ltd. DOM DT 20mg, DOM DT 5mg [Accessed on 03rd November 2022] https://www.morepen.com/medicus/antibiotics
Written By Dr. Priyanka Goel, BDS
Last updated on 10 Nov 2022 | 04:39 PM(IST)