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INTRODUCTION AFDERM MN + CREAM is a combination of Miconazole, Mometasone and Nadifloxacin which belongs to the group of medicines called Antifungals, Corticosteroids and Antibiotic respectively. It is used to treat bacterial and fungal skin infections like atopic and contact dermatitis, eryth...
AFDERM MN + CREAM is a combination of Miconazole, Mometasone and Nadifloxacin which belongs to the group of medicines called Antifungals, Corticosteroids and Antibiotic respectively. It is used to treat bacterial and fungal skin infections like atopic and contact dermatitis, erythema multiforme, infective eczema, psoriasis and skin lesions.
Bacterial infection occurs when bacteria enter the body, increase the number of bacteria and cause a reaction in the body A fungal infection (mycosis) is a skin disease that is caused by a fungus when it enters the tissue. Fungal infections can be contagious and spread from one person to another person.
Before using AFDERM MN + CREAM, inform your doctor if you have psoriasis. AFDERM MN + CREAM is not recommended for use during pregnancy.
AFDERM MN + CREAM should be used with caution in breastfeeding women unless considered clearly necessary.
AFDERM MN + CREAM is not recommended for use in children under 2 years of age and it should be used with caution in elderly patients.
The most common side effects of this medicine are application site reactions (such as burning, irritation, itching, flaking and redness). Contact your physician if any of the above symptoms worsen.
It is used to treat bacterial and fungal skin infections such as:
AFDERM MN + CREAM is a combination of Miconazole, Mometasone and Nadifloxacin. Miconazole works by causing holes in the cell membranes of the fungi and works against fungi. Mometasone is a corticosteroid that works by blocking the various chemical messengers (like histamine) involved in allergic and non-allergic mediated inflammation. It reduces inflammation, itchiness and redness by preventing the traveling of infection-fighting white blood cells (WBCs) to the affected area of the body. Nadifloxacin belongs to antibiotic works by against the bacteria that cause skin infections and also inhibits the repairing of bacterial cells, thereby preventing the further spread of the infections.
Apply AFDERM MN + CREAM as directed by your physician. It is for external use only. Apply a thin layer of the medicine to the affected area of the skin and rub it gently. Your doctor will decide the right dose depends on your age, body weight and severity of infection.
Stop applying AFDERM MN + CREAM and contact your physician immediately if you experience any of the following side effects:
Itchy skin:
Avoid hot baths because hot water can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if the itching worsens.
AFDERM MN + CREAM is not recommended for use during pregnancy unless considered clearly necessary. Contact your doctor before applying.
AFDERM MN + CREAM should be used with caution in breastfeeding women as it is not known whether it may pass through breast milk. Contact your doctor before applying.
AFDERM MN + CREAM does not affect the ability to drive or operate any machines. Consult your doctor before using AFDERM MN + CREAM.
Do not apply AFDERM MN + CREAM if you are allergic to Miconazole, Mometasone, Nadifloxacin or any other ingredients of this medicine.
AFDERM MN + CREAM is not recommended for use if you have:
Use in Pediatrics:
AFDERM MN + CREAM is not recommended for use in children under 2 years of age. Contact your doctor before using.
Use in Geriatrics:
In elderly patients, AFDERM MN + CREAM should be used with caution. Contact your doctor before using this medicine.
A. Drug - Drug interactions:
Before using AFDERM MN + CREAM, inform your doctor if you are taking any of the following medicine:
Overdosage:
If you or anyone else accidentally applies too much of AFDERM MN + CREAM or if you or a child accidentally swallow the medicine, consult your doctor immediately or visit the nearby hospital.
| Drug | : | Miconazole, Mometasone, Nadifloxacin |
| Pharmacological Category | : | Antifungals, Corticosteriods, Antibiotics |
| Therapeutic Indication | : | Bacterial and Fungal infections |
| Dosage Forms | : | Cream |
Q: What is the use of AFDERM MN + CREAM?
A: AFDERM MN + CREAM is a combination of Miconazole, Mometasone and Nadifloxacin which belongs to the group of medicines called Antifungal, Corticosteroid and Antibiotic respectively. It is used to treat bacterial and fungal skin infections like atopic and contact dermatitis, erythema multiforme, infective eczema, psoriasis and skin lesions. Consult your physician for advice before using AFDERM MN + CREAM.
Q: Is it safe to use AFDERM MN + CREAM in children?
A: AFDERM MN + CREAM is not recommended for use in children under 2 years of age. Contact your doctor before using AFDERM MN + CREAM.
Q: What are the common side effects of AFDERM MN + CREAM?
A: The most common side effects of AFDERM MN + CREAM are application site reactions (burning, irritation, itching, flaking and redness). Contact your physician if any of the symptoms does not improve.
Q: How to use AFDERM MN + CREAM?
A: Apply AFDERM MN + CREAM as directed by your physician. It is for external use only. Clean and dry the skin to be treated. Wash your hands with soap and water and apply a thin layer of the medicine to the affected area of the skin and rub it gently. Avoid contact with the eyes, nose, mouth or inside the vagina. Do not cover or wrap or bandage the skin unless directed by the doctor.
Q: Is AFDERM MN + CREAM safe to use during pregnancy and breastfeeding?
A: AFDERM MN + CREAM is not recommended to use during pregnancy unless considered clearly necessary. It should be used with caution in breastfeeding women as it is not known whether it may pass through breast milk. Contact your doctor before applying AFDERM MN + CREAM.
1. K.D. Tripathi. Antifungal Drugs, Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 787-797, 886-896.
2. Andrei Barasch & Andreea Voinea Griffin. Miconazole revisited: new evidence of antifungal efficacy from laboratory and clinical trials. Future Medicine. May 2008. [Accessed on 19th July 2022] https://www.futuremedicine.com/doi/10.2217/17460913.3.3.265
3. Duk Han Kim, Hyun Jong Lee, Chun Wook Park, Kyu Han Kim, Kwang Hoon Lee, Byung In Ro and Sang Hyun Cho. The Clinical Efficacy of Mometasone Furoate in Multi-Lamellar Emulsion for Eczema: A Double-blinded Crossover Study. Annals of Dermatology. February 2013. [Accessed on 19th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582923/
4. Varsha Narayanan, Salman Motlekar, Ganesh Kadhe and Seema Bhagat. Efficacy and Safety of Nadifloxacin for Bacterial Skin Infection: Results from Clinical and Post-Marketing Studies. Journal of Dermatology and Therapy. December 2014. [Accessed on 19th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257952/
5. Hacks & Slacks Healthcare. Nanomom – MN Cream. [Accessed on 19th July 2022] https://www.hacksslackshealthcare.com/product/nanomom-mn-cream
6. Leeford. Inc. NADIMIN M2. [Accessed on 19th July 2022] https://www.leeford.in/product/1406/nadimin-m2
7. Yester Pharma Pvt Ltd. OANADI-MM. [Accessed on 19th July 2022] https://www.yesterpharma.com/product/oanadi-mm/
8. CANBRO Healthcare. NADIX-M. [Accessed on 19th July 2022] https://www.canbro.in/product/nadifloxacin-10mg-mometasone-furoate-1mg-miconazole-nitrate-20mg-cr
9. Berko Ilaç ve Kimya Sanayi A.S. Electronic Medicines Compendium (EMC). [Revised in January 2016] [Accessed on 19th July 2022] http://berkoilac.com.tr/wp-content/uploads/2018/08/aknefloks-cream-PIL-revH.pdf
10. Glenmark Pharmacuticals Europe Ltd. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 19th July 2022] https://www.medicines.org.uk/emc/files/pil.9994.pdf
11. Janssen - Cilag Ltd. Electronic Medicines Compendium (EMC). [Revised in August 2020] [Accessed on 19th July 2022] https://www.medicines.org.uk/emc/files/pil.1435.pdf
Written By Dr. Janet.C, Pharm.D
Last updated on 31 Dec 2022 | 07:30 PM(IST)