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INTRODUCTION BREVIPIL ORAL SOLUTION contains Brivaracetam, which belongs to the group of medicines called anti-epileptics. It is used to treat epilepsy. Epilepsy is a chronic non-communicable disease of the brain, characterized by recurrent seizures, which are small episodes of involuntary mov...
BREVIPIL ORAL SOLUTION contains Brivaracetam, which belongs to the group of medicines called anti-epileptics. It is used to treat epilepsy. Epilepsy is a chronic non-communicable disease of the brain, characterized by recurrent seizures, which are small episodes of involuntary movement that may involve a part of the body (partial) or the entire body (generalized) and are sometimes associated with loss of consciousness and control of bowel or bladder function.
BREVIPIL ORAL SOLUTION is not recommended to use in patients with severe liver problems. BREVIPIL ORAL SOLUTION is generally not recommended for use in pregnant and breastfeeding women unless considered necessary. BREVIPIL ORAL SOLUTION is not recommended for use in children under 4 years of age. Consult your doctor before taking BREVIPIL ORAL SOLUTION.
The most common side effects of taking BREVIPIL ORAL SOLUTION are feeling sleepy or dizzy, flu, feeling very tired, convulsion (a feeling of spinning), feeling and being sick and constipation, depression, anxiety, not being able to sleep, irritability, infection of nose and throat and decreased appetite. Contact your doctor if any of the symptoms get worse or persist.
Brivaracetam works by attaching itself to specific sites (SV2A) on the nerve cells’ suppresses the abnormal activity of the nerve cells in the brain and prevents the spread of electrical signals that cause seizures.
Take BREVIPIL ORAL SOLUTION as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.
Nausea or vomiting:
Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods. Consult your doctor immediately if your symptom gets worse or persist.
Constipation:
Eat plenty of fiber-rich foods such as fresh fruits, vegetables, and cereals, and drink plenty of water. Exercise more regularly. Consult your doctor immediately if your symptom gets worse or persist.
BREVIPIL ORAL SOLUTION is generally not recommended for use in pregnant women unless considered necessary. Consult your doctor before taking BREVIPIL ORAL SOLUTION.
BREVIPIL ORAL SOLUTION is generally not recommended for use in breastfeeding women as it may pass through breast milk. Consult your doctor before taking BREVIPIL ORAL SOLUTION.
Do not drive or operate any machines if you feel sleepy, dizzy, or tired while taking BREVIPIL ORAL SOLUTION.
Avoid consumption of alcohol while taking BREVIPIL ORAL SOLUTION.
BREVIPIL ORAL SOLUTION is not recommended for use in patients with impaired renal function. Consult your doctor before taking BREVIPIL ORAL SOLUTION.
BREVIPIL ORAL SOLUTION should be taken with caution in patients with hepatic impairment. Consult your doctor before taking BREVIPIL ORAL SOLUTION.
Do not take BREVIPIL ORAL SOLUTION if you are allergic to brivaracetam or other similar chemical compounds such as levetiracetam or piracetam or any other ingredients of BREVIPIL ORAL SOLUTION.
Before taking BREVIPIL ORAL SOLUTION, inform your doctor if you have:
Use in pediatrics:
BREVIPIL ORAL SOLUTION is not recommended for use in children under 4 years of age. Consult your doctor before taking BREVIPIL ORAL SOLUTION.
Use in geriatrics:
BREVIPIL ORAL SOLUTION should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking BREVIPIL ORAL SOLUTION.
Before taking BREVIPIL ORAL SOLUTION, inform your doctor if you are taking any of the following medicine:
Overdosage:
If you or anyone else accidentally take too much of BREVIPIL ORAL SOLUTION, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include dizziness, sleepy, feeling sick, a feeling of ‘spinning’, problems keeping your balance, anxiety, tiredness, irritability, being aggressive, inability to sleep, depression, thoughts or attempts of harming or killing yourself.
| Drug | : | Brivaracetam |
| Pharmacological Category | : | Anti-epileptics |
| Therapeutic Indication | : | Epilepsy |
| Dosage Forms | : | Tablet, Injection, Oral solution, syrup |
Can BREVIPIL ORAL SOLUTION be given to children at 2 years?
BREVIPIL ORAL SOLUTION should not be given to children below 4 years of age. Consult your doctor before taking BREVIPIL ORAL SOLUTION.
How to take BREVIPIL ORAL SOLUTION?
Take BREVIPIL ORAL SOLUTION as advised by your physician. Shake well before use. BREVIPIL ORAL SOLUTION can be taken as such or can be diluted with water before taking. BREVIPIL ORAL SOLUTION can be taken with or without food.
What are the precautions to be taken if BREVIPIL ORAL SOLUTION is taken in excess?
If you or anyone else accidentally take too much of BREVIPIL ORAL SOLUTION, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include dizziness, sleepy, feeling sick, a feeling of ‘spinning’, problems keeping your balance, anxiety, tiredness, irritability, being aggressive, inability to sleep, depression, thoughts or attempts of harming or killing yourself.
How do BREVIPIL ORAL SOLUTION act?
Brivaracetam works by attaching itself to specific sites (SV2A) on the surfaces of nerve cells which suppresses the abnormal activity of the nerve cells in the brain and prevents the spread of electrical signals that cause seizures.
Will BREVIPIL ORAL SOLUTION affect my ability to drive or use the machine?
Do not drive or operate machinery until you know how BREVIPIL ORAL SOLUTION affects you. BREVIPIL ORAL SOLUTION may cause drowsiness, tiredness, dizziness, and problems with your balance and coordination.
Who should not take BREVIPIL ORAL SOLUTION?
Do not take BREVIPIL ORAL SOLUTION if you are allergic to brivaracetam or any of the ingredients in BREVIPIL ORAL SOLUTION.
What are the most common side effects of BREVIPIL ORAL SOLUTION?
The most common side effects of taking BREVIPIL ORAL SOLUTION are feeling sleepy or dizzy, flu, feeling very tired, convulsion (a feeling of spinning), feeling and being sick and constipation, depression, anxiety, not being able to sleep, irritability, infection of nose and throat and decreased appetite. Contact your doctor if any of the symptoms worsen.
1. Misty D. Smith, Cameron S. Metcalf, and Karen S. Wilcox. Pharmacotherapy of the Epilepsies. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018 Page – 303-326.
2. Felix Zahnert, Kristina Krause, Ilka Immisch, Lena Habermehl, Iris Gorny, Izabella Chmielewska, Leona Möller, Anna M. Weyand, Peter M. Mross, Jan Wagner, Katja Menzler and Susanne Knake. Brivaracetam in the Treatment of Patients with Epilepsy - First Clinical Experiences. Journal of Frontiers in neurology. February 2018. [Accessed on 2nd May 2022] https://www.frontiersin.org/articles/10.3389/fneur.2018.00038/full
3. Farbod Khaleghi, and Eric C. Nemec. A Novel Adjunctive Therapy for Partial-Onset Seizures. February 2017. [Accessed on 2nd May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5265234/
4. UCB Pharma limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 2nd May 2022] https://www.medicines.org.uk/emc/files/pil.1964.pdf
Written By Dr. Dhivakaran R, BDS
Last updated on 22 Oct 2022 | 11:03 AM(IST)