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INTRODUCTION ACTIGLIPT M 20/500MG TABLET is a combination of Metformin and Teneligliptin which belongs to the group of medicines called Antidiabetic agents. It is used to manage type II diabetes mellitus among patients when diet, exercise and management with other conventional medicines does n...
ACTIGLIPT M 20/500MG TABLET is a combination of Metformin and Teneligliptin which belongs to the group of medicines called Antidiabetic agents. It is used to manage type II diabetes mellitus among patients when diet, exercise and management with other conventional medicines does not result in adequate control on blood glucose levels.
Type II diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood. It is caused due to inadequate production of a hormone called insulin (produced by pancreas to metabolize glucose) in the body or due to inadequate sensitivity of body cells to the actions of insulin.
Before taking ACTIGLIPT M 20/500MG TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have low potassium levels in blood or are severely dehydrated due to excessive vomiting or diarrhea recently.
During therapy with ACTIGLIPT M 20/500MG TABLET, your doctor might regularly monitor your blood sugar levels and kidney functions to avoid the risk of unwanted side effects. He/she might also ask you to make certain lifestyle changes such as following a healthy diet, regular physical exercise and quitting alcohol consumption to achieve better results.
ACTIGLIPT M 20/500MG TABLET is not recommended for use in patients with severe uncontrollable diabetes. It is also not suitable for use in patients with alcoholism and in patients with severe systemic infections.
Consult your doctor before taking ACTIGLIPT M 20/500MG TABLET if you are pregnant or breastfeeding. The most common side effects of taking ACTIGLIPT M 20/500MG TABLET are low blood sugar levels, stomach upset, constipation, flatulence and altered taste sensations. Consult your doctor if they bother you.
ACTIGLIPT M 20/500MG TABLET is an antidiabetic medicine. It contains two medicines namely metformin and teneligliptin. Metformin makes the body more sensitive to insulin (a hormone involved in glucose metabolism). This helps our body cells to utilize more amount of the circulating blood glucose. Additionally, it can stop glucose production by the liver and reduces its absoprtion in the body.
Teneligliptin controls blood sugar levels by blocking the actions of an enzyme called dipeptidyl peptidase (DPP)-4 that reduces insulin secretion in the body. Collectively, ACTIGLIPT M 20/500MG TABLET controls blood sugar levels and improve glycemic control in patients with type II diabetes.
Take ACTIGLIPT M 20/500MG TABLET preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking ACTIGLIPT M 20/500MG TABLET unless your doctor advice you to stop.
Stop taking ACTIGLIPT M 20/500MG TABLET and consult your doctor immediately if you experience any of the following side effects:
Taking ACTIGLIPT M 20/500MG TABLET with meals may reduce the chances of constipation. However, if you experience constipation, eat plenty of fiber rich foods such as fresh fruits, vegetables and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Have foods rich in sugars such as fruit juices, glucose drinks, candies, honey or biscuits. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack or a drink and check your blood sugar levels once again. Contact your doctor if there is no improvement in your condition.
ACTIGLIPT M 20/500MG TABLET should be used in pregnant women only if considered necessary by the physician. Your doctor will prescribe ACTIGLIPT M 20/500MG TABLET only if the therapeutic benefits overweigh the risk to the fetus. Therefore, inform your doctor before taking it.
ACTIGLIPT M 20/500MG TABLET is not recommended for use in breastfeeding women. However, consult your doctor before taking it.
Do not drive or operate any machines if you feel dizzy after taking ACTIGLIPT M 20/500MG TABLET.
Avoid consumption of alcohol while taking ACTIGLIPT M 20/500MG TABLET as it may increase the risk of unwanted side effects.
ACTIGLIPT M 20/500MG TABLET is not recommended for use in patients with severely reduced kidney functions. Therefore, consult your doctor before taking it.
ACTIGLIPT M 20/500MG TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with gall stones. Therefore, consult your doctor before taking it.
Do not take ACTIGLIPT M 20/500MG TABLET if you are allergic to Metformin or Teneligliptin.
ACTIGLIPT M 20/500MG TABLET is not recommended for use in patients with severe infections of the lungs or respiratory tract. Therefore, consult your doctor before taking it.
ACTIGLIPT M 20/500MG TABLET is not recommended for use in patients with severe heart problems (such as acute heart failure, recent heart attack, arrythmia, prolonged QT interval). Therefore, consult your doctor before taking it.
The safety and effectiveness of ACTIGLIPT M 20/500MG TABLET have not been established in infants, children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
The safety and effectiveness of ACTIGLIPT M 20/500MG TABLET have not been established in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.
ACTIGLIPT M 20/500MG TABLET is not recommended for use if you:
Before taking ACTIGLIPT M 20/500MG TABLET, inform your doctor if you:
A. Drug-Drug interactions:
Before taking ACTIGLIPT M 20/500MG TABLET, inform your doctor if you are taking any of the following medicines such as:
Overdosage:
If you or anyone else accidentally took more ACTIGLIPT M 20/500MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are feeling cold or uncomfortable, severe nausea or vomiting, stomach pain, unexplained weight loss, muscular cramps and fast breathing.
| Drug | : | Metformin, Teneligliptin |
| Pharmacological Category | : | Biguanides, DPP-4 Inhibitors |
| Therapeutic Indication | : | Type II Diabetes mellitus |
| Dosage Forms | : | Tablet |
Q: What is ACTIGLIPT M 20/500MG TABLET used for?
A: ACTIGLIPT M 20/500MG TABLET is an antidiabetic medicine used as an adjunct to diet and exercise to control blood sugar levels in patients with type II diabetes mellitus.
Q: How and when to take ACTIGLIPT M 20/500MG TABLET?
A: Take ACTIGLIPT M 20/500MG TABLET preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not cursh or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: How long should I take ACTIGLIPT M 20/500MG TABLET?
A: You need to take ACTIGLIPT M 20/500MG TABLET as long as your doctor prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: What is the best time to take ACTIGLIPT M 20/500MG TABLET?
A: ACTIGLIPT M 20/500MG TABLET must be taken with meals to avoid gastrointestinal side effects.
Q: What to do if I forgot to take a dose of ACTIGLIPT M 20/500MG TABLET?
A: If you forgot to take a dose of ACTIGLIPT M 20/500MG TABLET, take it as soon as you remember. However, if it is time for the next dose of ACTIGLIPT M 20/500MG TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of ACTIGLIPT M 20/500MG TABLET to compensate the missed ones.
Q: What are the most common side effects of taking ACTIGLIPT M 20/500MG TABLET?
A: The most common side effects of taking ACTIGLIPT M 20/500MG TABLET are low blood sugar levels, stomach upset, constipation, flatulence, metallic taste in mouth, sore throat, stuffy nose and joint pain. Consult your doctor if they bother you.
Q: Can I stop taking ACTIGLIPT M 20/500MG TABLET without consulting your doctor?
A: No. You should not stop taking ACTIGLIPT M 20/500MG TABLET without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using ACTIGLIPT M 20/500MG TABLET, consult your doctor for advice.
Q: Will taking a higher dose of ACTIGLIPT M 20/500MG TABLET be more effective?
A: No, taking a higher dose of ACTIGLIPT M 20/500MG TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Q: What precautions do I need to follow while taking ACTIGLIPT M 20/500MG TABLET?
A: Before taking ACTIGLIPT M 20/500MG TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have severe systemic infections or are severely dehydrated due to excessive vomiting or diarrhea recently. Along with the therapy, follow the diet and lifestyle changes advised by your doctor to achieve better results. Consult your doctor before taking ACTIGLIPT M 20/500MG TABLET if you are pregnant or breastfeeding.
Q: Can I take medication for high blood pressure along with ACTIGLIPT M 20/500MG TABLET?
A: It is not advisable to take medicines to control blood pressure while taking ACTIGLIPT M 20/500MG TABLET without consulting your doctor. Therefore, consult your doctor before taking any antihypertensive such as beta blockers (Ex. atenolol, propranolol) along with ACTIGLIPT M 20/500MG TABLET as they have known interactions with ACTIGLIPT M 20/500MG TABLET.
Q: What should I do if I experience low blood sugar after taking ACTIGLIPT M 20/500MG TABLET?
A: Low blood sugar is a common side effect of taking ACTIGLIPT M 20/500MG TABLET. If you experience any signs of low blood sugar levels (such as increased hunger, sweating, shakiness, weakness or an irregular heartbeat), consume a sugary snack or sugar drink immediately. Consult your doctor if the symptom did not improve.
Q: Can ACTIGLIPT M 20/500MG TABLET be taken with insulin?
A: Co-administration of ACTIGLIPT M 20/500MG TABLET with insulin is considered risky as they are increased chances of hypoglycemia (decreased blood sugar levels). Therefore, consult your doctor before taking it.
Q: Can ACTIGLIPT M 20/500MG TABLET be used in pregnant women?
A: ACTIGLIPT M 20/500MG TABLET should be used in pregnant women only if considered necessary by the physician. Your doctor will prescribe ACTIGLIPT M 20/500MG TABLET only if the therapeutic benefits overweigh the risk to the fetus. Therefore, inform your doctor before taking it.
Q: How to take ACTIGLIPT M 20/500MG TABLET?
A: You must take ACTIGLIPT M 20/500MG TABLET as advised by your physician. Try to take this medicine preferably after meals and swallow it with a glass of water. Do not crush or chew the medicine.
Q: How much ACTIGLIPT M 20/500MG TABLET should I take?
A: ACTIGLIPT M 20/500MG TABLET should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.
Q: Can ACTIGLIPT M 20/500MG TABLET cause constipation?
A: Yes. Constipation is a common side effect of using ACTIGLIPT M 20/500MG TABLET. Eat plenty of fiber rich foods such as fresh fruits, vegetables, cereals as well as drink plenty of water and exercise more regularly while taking this medicine. Contact your doctor if this side effect bothers you.
1. KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 274 & 275.
2. Linong Ji, Ling Li, Jianhua Ma, Xuefeng Li, Dongmei Li, Bangzhu Meng, Weiping Lu, Jiao Sun, Yanmei Liu, Gen Takayanagi and Yi Wang. Efficacy and safety of teneligliptin added to metformin in Chinese patients with type 2 diabetes mellitus inadequately controlled with metformin: A phase 3, randomized, double-blind, placebo-controlled study. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. January 2021. [Accessed on 27th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8029565/
3. Rx Farma Limited. Electronic Medicines Compendium (EMC). [Revised in September 2019] [Accessed on 27th October 2022] https://www.medicines.org.uk/emc/files/pil.11951.pdf
4. Torrent Pharmaceutical Ltd. Teneligliptin. [Revised in April 2021] [Accessed on 27th October April 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2991.pdf
5. Centaur Pharmaceuticals Pvt Ltd. TEN20 – M. [Accessed on 27th October 2022] https://www.centaurpharma.com/downloads/Ten20M2018.pdf
6. Johnlee Pharmaceuticals Pvt Ltd. TENALIP-M 1000. [Accessed on 27th October 2022] http://johnleeindia.com/product/tenalip-m-1000/
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 21 Oct 2023 | 04:06 PM(IST)