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INTRODUCTION ACCUGLIM MP is a combination of Glimepiride, Metformin and Pioglitazone which belongs to the group of medicines called Antidiabetic agents. It is used in adults to manage type II diabetes mellitus when diet, exercise and management with single agent does not result in adequate sug...
ACCUGLIM MP is a combination of Glimepiride, Metformin and Pioglitazone which belongs to the group of medicines called Antidiabetic agents. It is used in adults to manage type II diabetes mellitus when diet, exercise and management with single agent does not result in adequate sugar control.
Type II diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood. It is caused due to inadequate production of a hormone called insulin (produced by pancreas to metabolize glucose) in the body or due to inadequate sensitivity of body cells to the actions of insulin.
Before taking ACCUGLIM MP, inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any eye problems, hormonal imbalance, alcoholism, or if you are malnourished, starved, on an irregular diet as a precaution.
ACCUGLIM MP is strictly not recommended for use in patients with type I diabetes mellitus, bladder cancer, severe heart failure or lactic acidosis. It is also not suitable for use in pregnant or breastfeeding women.
Along with the management, follow the diet and lifestyle changes advised by your doctor to achieve better results. Avoid smoking and consumption of alcohol while taking ACCUGLIM MP as it may aggravate your existing condition.
The most common side effects of taking ACCUGLIM MP are low blood sugar levels, nausea, stomach upset, constipation, sore throat, muscle pain, headache, dizziness and weight gain. Consult your doctor if any of these side effect worsens.
ACCUGLIM MP stimulates the pancreas to secrete more insulin (a hormone involved in glucose metabolism). It also makes our body more sensitive to insulin which helps in digesting the circulating sugars (glucose) in the blood, thereby reducing blood sugar levels. Additionally, it can also reduce the glucose produced by the liver and reduces its absoprtion in the body.
Take ACCUGLIM MP preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Do not stop taking ACCUGLIM MP unless your doctor advice you to stop.
Stop taking ACCUGLIM MP and contact your doctor immediately if you experience any of the following side effects:
Hydrate yourself by drinking plenty of fluids, such as water or fruit juices. Consuming ORS can also be beneficial. Do not self-treat diarrhea on your own. Consult your doctor if your diarrhea becomes uncontrollable.
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol. Consult your doctor if your dizziness worsens.
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Have foods rich in sugars such as fruit juices, glucose drinks, candies, honey or biscuits. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or a drink and check the blood sugar again. Consult your doctor if there is no improvement in your condition.
Take ACCUGLIM MP with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if your nausea worsens.
ACCUGLIM MP is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
ACCUGLIM MP is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
Do not drive or operate any heavy tools or machines if your ability is affected by ACCUGLIM MP.
Avoid consumption of alcohol while taking ACCUGLIM MP as it may increase the risk of unwanted side effects.
ACCUGLIM MP is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems. Therefore, consult your doctor before taking it.
ACCUGLIM MP is not recommended for use in patients with severe liver problems. It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it.
Do not take ACCUGLIM MP if you are allergic to Glimepiride, Metformin, Pioglitazone or to any other sulfonylureas (Ex. glyburide, gliclazide) or sulphonamides (Ex. sulfasalazine).
ACCUGLIM MP is not recommended for use in patients with severe heart problems (such as heart failure). It should be used with caution in patients with other heart problems. Therefore, consult your doctor before taking it.
ACCUGLIM MP is not recommended for use in children and in adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
ACCUGLIM MP should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before taking it.
ACCUGLIM MP is not recommended for use if you:
Before taking ACCUGLIM MP, inform your doctor if you:
A. Drug-Drug Interactions:
Before taking ACCUGLIM MP, inform your doctor if you are taking any of the following medicines:
Overdosage:
If you or anyone else accidentally took more ACCUGLIM MP, you may experience the signs of hypoglycemia (such as increased hunger, sweating, headache, feeling clammy, restless or aggressive, shakiness, fast heartbeat and confusion). To manage this, consume any sugary food immediately. If the symptom did not improve or worsens contact your doctor immediately. Other symptoms of overdosage might include vomiting, stomach pain with muscle cramps, feeling generally unwell with severe tiredness and difficulty in breathing.
| Drug | : | Glimepiride, Metformin, Pioglitazone |
| Pharmacological Category | : | Sulfonylureas, Biguanides, PPAR-gamma and PPAR-alpha agonists |
| Therapeutic Indication | : | Type II diabetes mellitus |
| Dosage Forms | : | Tablet |
Q: What is ACCUGLIM MP used for?
A: ACCUGLIM MP is an antidiabetic medicine used to manage type II diabetes mellitus when diet, exercise and management with single agent does not result in adequate response.
Q: How and when to take ACCUGLIM MP?
A: Take ACCUGLIM MP preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not cursh or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: How long should I take ACCUGLIM MP?
A: You need to take ACCUGLIM MP as long as your doctor or physician prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: What is the best time to take ACCUGLIM MP?
A: ACCUGLIM MP must be taken with meals to avoid gastrointestinal side effects.
Q: What to do if I forgot to take a dose of ACCUGLIM MP?
A: If you forgot to take a dose of ACCUGLIM MP, take it as soon as you remember. However, if it is time for the next dose of ACCUGLIM MP, skip the missed dose and take the next one regularly. Do not take a double dose of ACCUGLIM MP to compensate the missed ones.
Q: Can I stop taking ACCUGLIM MP without consulting your doctor?
A: No. You should not stop taking ACCUGLIM MP without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using ACCUGLIM MP, consult your doctor for advice.
Q: Will taking a higher dose of ACCUGLIM MP be more effective?
A: No, taking a higher dose of ACCUGLIM MP will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Q: Can I take medication for high blood pressure along with ACCUGLIM MP?
A: It is not advisable to take medicines to control blood pressure while taking ACCUGLIM MP without consulting your doctor, as they have known interactions with ACCUGLIM MP.
Q: How to manage the side effects of ACCUGLIM MP?
A: Low blood sugar is a common side effect of taking ACCUGLIM MP. Try to have sugar rich food items such as fruit juice, glucose tablets or gel, soft drinks, honey or sugary candy. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or drink, and check the blood sugar levels once again. If your condition did not improve, consult your doctor immediately.
Q: Can ACCUGLIM MP be taken with insulin?
A: Co-administration of ACCUGLIM MP with insulin is considered risky as they can increase the chances of hypoglycemia (low blood sugar levels). Therefore, consult your doctor before taking it.
Q: Can ACCUGLIM MP be used in pregnant women?
A: ACCUGLIM MP is not recommended for use in pregnant women. Therefore, consult your doctor for advice before taking it.
Q: Does ACCUGLIM MP cause bone fractures?
A: ACCUGLIM MP may cause bone fractures in some individuals. Therefore, it is important for you to inform your doctor before taking ACCUGLIM MP if you have any bone problems or at risk of developing any bone fractures (such as menopause).
Q: Does ACCUGLIM MP cause weight gain?
A: Yes. ACCUGLIM MP may cause weight gain in some individuals. To avoid this, follow a healthy diet and regular physical activity as advised by your physician. However, if you experience any weight gain due to swelling of body parts (such as in face, legs, or hands), consult your doctor immediately.
Q: What are the side effects of taking ACCUGLIM MP?
A: The most common side effects of taking ACCUGLIM MP are low blood sugar levels, nausea, stomach upset, constipation, sore throat, muscle pain, headache, dizziness and weight gain. Consult your doctor if any of these side effect worsens.
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Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 18 Oct 2023 | 05:02 PM(IST)