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INTRODUCTION ABVIDA M 50/500MG TABLET is a combination of Metformin and Vildagliptin , which belongs to a group of medicines called Antidiabetic agents. ABVIDA M 50/500MG TABLET is used to manage type 2 diabetes (also known as non-insulin-dependent diabetes melli...
ABVIDA M 50/500MG TABLET is a combination of Metformin and Vildagliptin , which belongs to a group of medicines called Antidiabetic agents. ABVIDA M 50/500MG TABLET is used to manage type 2 diabetes (also known as non-insulin-dependent diabetes mellitus) in adult patients whose diabetes cannot be controlled by diet and exercise alone and/or with other medicines used to manage diabetes (insulin or sulphonylureas such as glimepiride and glipizide).
Type 2 diabetes is a chronic medical condition in which the body does not make enough insulin, or the insulin that is produced does not work well. Symptoms include excessive urination, excessive thirst, hunger, fatigue, and blurred vision.
Before taking ABVIDA M 50/500MG TABLET, inform your doctor if you have liver, kidney, or heart problems. It should be used during pregnancy only if advised by your doctor, and it is not recommended for pregnant women. ABVIDA M 50/500MG TABLET is not suitable for use in children and adolescents under 18 years of age, and it should be used with caution in elderly patients (65 years of age and above).
Avoid consumption of alcohol during treatment with ABVIDA M 50/500MG TABLET, as it may increase the risk of lactic acidosis. The most common side effects of taking ABVIDA M 50/500MG TABLET are nausea, vomiting, stomach pain, headache, low blood sugar, and diarrhea. Contact your doctor if any of the symptoms worsen.
ABVIDA M 50/500MG TABLET helps to control the blood sugar level, where metformin makes the body more sensitive to insulin (a hormone involved in glucose metabolism). This helps our body cells utilize more of the circulating blood glucose. Additionally, it can stop glucose production by the liver and reduce its absorption in the body.
Vildagliptin controls blood sugar levels by blocking the actions of an enzyme called dipeptidyl peptidase (DPP)-4 that indirectly increases insulin secretion in the body. Collectively, ABVIDA M 50/500MG TABLET controls blood sugar levels in patients with type II diabetes.
Always take ABVIDA M 50/500MG TABLET as directed by your physician. Take this medicine with or just after the food, swallow the medicine as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you, depending on your age and health condition. Do not stop taking ABVIDA M 50/500MG TABLET without informing your doctor.
Stop taking ABVIDA M 50/500MG TABLET and contact your doctor immediately if you experience any of the following side effects:
Consume fiber-rich foods such as fresh fruits and vegetables, whole-grain cereals, and plenty of fluids. Exercise more regularly and stay active. Consult your doctor if the symptom does not improve.
Drink lots of fluids, such as water or fruit juices, to keep yourself hydrated. Avoid taking any medicine on your own to treat diarrhoea. Consult your doctor if the symptom does not improve.
Rest and relax. Drink a sufficient amount of fluids, such as water. Apply a pain-relieving balm to the head if required. Consult your doctor if the symptom does not improve.
Stick to simple meals. Avoid eating oily, fried, or spicy food. Do not perform any strenuous activities immediately after eating. Consult your doctor if the symptom does not improve.
Rest and relax. Eat and drink slowly, or try to have smaller and more frequent meals. Keep a heating pad on your stomach. Do not self-treat on your own; consult your doctor if the symptom does not improve on its own.
ABVIDA M 50/500MG TABLET is generally not recommended for pregnant women unless it is considered necessary. Consult your doctor before taking ABVIDA M 50/500MG TABLET.
ABVIDA M 50/500MG TABLET is not recommended for use by breastfeeding women. Consult your doctor before taking ABVIDA M 50/500MG TABLET.
Do not drive or operate any machines if you experience dizziness after taking ABVIDA M 50/500MG TABLET.
Consumption of alcohol is not recommended during treatment with ABVIDA M 50/500MG TABLET since it may increase the risk of lactic acidosis.
ABVIDA M 50/500MG TABLET is not recommended in patients with severely reduced kidney function. Consult your doctor before taking ABVIDA M 50/500MG TABLET.
ABVIDA M 50/500MG TABLET is not recommended in patients with liver disease. Consult your doctor before taking ABVIDA M 50/500MG TABLET.
Do not take ABVIDA M 50/500MG TABLET if you are allergic (hypersensitive) to metformin or vildagliptin.
ABVIDA M 50/500MG TABLET is not recommended in patients who recently had a heart attack or heart failure or any signs of heart problems such as serious blood circulation problems or difficulty breathing. Consult your doctor before taking ABVIDA M 50/500MG TABLET.
ABVIDA M 50/500MG TABLET is not recommended for use in children and adolescents less than 18 years of age due to a lack of safety and effectiveness. Consult with your doctor for advice.
ABVIDA M 50/500MG TABLET should be used with caution in elderly patients above 65 years of age, especially in patients with impaired kidney function. Your doctor will adjust the dose depending on kidney function, and your kidney function will be monitored regularly. Consult with your doctor before taking ABVIDA M 50/500MG TABLET.
ABVIDA M 50/500MG TABLET is not recommended for you if you have:
Before taking ABVIDA M 50/500MG TABLET, inform your doctor if you have or had:
A. Drug-Drug interactions:
Before taking ABVIDA M 50/500MG TABLET, inform your doctor if you are taking any of these medicines:
Overdosage:
If you or anyone else accidentally takes too much of ABVIDA M 50/500MG TABLET, consult your doctor immediately. Overdosage symptoms of ABVIDA M 50/500MG TABLET might include low blood sugar levels, lactic acidosis, muscle pain, mild and transient burning or tickling sensations in the body, fever, and oedema.
| Drug | : | Metformin and Vildagliptin |
| Pharmacological Category | : | Antidiabetic agent (Biguanides & Dipeptidyl Peptidase 4 inhibitor) |
| Therapeutic Indication | : | Type 2 Diabetes Mellitus |
| Dosage Forms | : | Tablet |
Q: What is ABVIDA M 50/500MG TABLET used for?
A: ABVIDA M 50/500MG TABLET is used to manage type 2 diabetes (also known as non-insulin-dependent diabetes mellitus) in adults whose diabetes cannot be controlled by diet and exercise alone and/or in combination with other diabetes medications (insulin or sulphonylureas such as glimepiride or glipizide).
Q: Is it safe to use ABVIDA M 50/500MG TABLET on elderly patients?
A: ABVIDA M 50/500MG TABLET should be used with caution in elderly patients over 65 years of age, especially in patients with impaired kidney function. Your doctor will adjust the dose depending on kidney function, and your kidney function will be monitored regularly. Consult with your doctor before taking ABVIDA M 50/500MG TABLET.
Q: Is it safe to use ABVIDA M 50/500MG TABLET in patients with heart problems?
A: ABVIDA M 50/500MG TABLET is not recommended in patients who have recently had a heart attack, heart failure, or any signs of heart problems such as serious problems with blood circulation or difficulty breathing. Consult your doctor before taking ABVIDA M 50/500MG TABLET.
Q: What are the most common side effects of taking ABVIDA M 50/500MG TABLET?
A: The most common side effects of taking ABVIDA M 50/500MG TABLET are nausea, vomiting, stomach pain, headache, dizziness, loss of appetite, metallic taste, uncontrolled trembling, low blood sugar, and diarrhea. Contact your doctor if any of the symptoms worsen.
Q: Can I consume alcohol while taking ABVIDA M 50/500MG TABLET?
A: Consumption of alcohol is not recommended during treatment with ABVIDA M 50/500MG TABLET since it may increase the risk of lactic acidosis. Consult your doctor before taking ABVIDA M 50/500MG TABLET if you are an alcoholic or have a history of alcoholism.
1. KD Tripathi MD. Hormones and related drugs. Essentials of Medical Pharmacology. Seventh edition. New Delhi, May 2013. Page – 274.
2. Paresh Ved and Samrat Shah. Evaluation of vildagliptin and fixed dose combination of vildagliptin and metformin on glycemic control and insulin dose over 3 months in patients with type 2 diabetes mellitus. March 2012. [Accessed on 30th June 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354946/
3. Serge Halimi, Anja Schweizer, Biljana Minic, James Foley and Sylvie Dejage. Combination treatment in the management of type 2 diabetes: focus on vildagliptin and metformin as a single tablet. March 2008. [Accessed on 30th June 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515409/
4. Novartis Pharma GmbH. Electronic Medicines Compendium (EMC) [Revised in August 2021] [Accessed on 30th June 2021] https://www.medicines.org.uk/emc/files/pil.6226.pdf
5. Cipla Ltd. VYSOV-M Tablets (Vildagliptin + Metformin hydrochloride). [Revised in July 2020] [Accessed on June 30, 2021] https://ciplamed.com/print-product-pdf/37162
Written By Dr. N. Sai Swaroop, Pharm.D
Last updated on 17 Jan 2024 | 10:08 AM(IST)