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INTRODUCTION ABVIDA D TABLET is a combination of Dapagliflozin and Vildagliptin which belongs to the group of medicines called Antidiabetic agents. It is used in adults to manage type II diabetes mellitus which is poorly controlled on metformin monotherapy....
ABVIDA D TABLET is a combination of Dapagliflozin and Vildagliptin which belongs to the group of medicines called Antidiabetic agents. It is used in adults to manage type II diabetes mellitus which is poorly controlled on metformin monotherapy.
Type 2 diabetes is a condition in which your body fails to make enough insulin, and the insulin that is produced does not work as well as it should. This results in sugar (glucose) build-up in the blood and thus increased blood sugar levels. You should follow the recommendations for skin and foot care that you are given by your doctor.
Before taking ABVIDA D TABLET, inform your doctor if you have any liver, kidney, pancreatic or heart disease, or if you are undergoing dialysis. ABVIDA D TABLET is not recommended for use in pregnant women, breastfeeding woman, children and adolescents (below 18 years of age) so, consult your doctor for advice,
Your doctor might ask you to take certain blood tests to check your liver function and to examine that the treatment is having the desired effect. The most common side effects of taking ABVIDA D TABLET are dizziness, genital infection (thrush) of penis or vagina, back pain, frequent or excessive urination than normal and rash. Call your doctor if the symptoms do not improve.
ABVIDA D TABLET effectively lowers blood sugar levels where Dapagliflozin inhibits the sodium-glucose cotransporter 2 (SGLT2) in kidneys which allows excretion of excessive glucose through urine, and Vildagliptin decreases the glucose production in liver and increases the insulin sensitivity to absorb glucose.
Always take ABVIDA D TABLET as directed by your physician. Swallow with a glass of water. Do not chew or crush the medicine. Your doctor will advise the suitable dose and duration of treatment depending upon your age, body weight and disease condition. Do not stop taking ABVIDA D TABLET unless your doctor advises you to stop.
Stop taking ABVIDA D TABLET and contact your doctor immediately if you experience any of the following side effects:
To avoid dehydration of your body, drink plenty of fluids such as water, fruit juices or electrolytes. If symptom persists, contact your doctor.
Lie, or sit down promptly when you feel dizzy. If you're feeling severe episode of spinning, lie in a dark and quite place and close your eyes. Try to avoid vehicle driving. If symptom persists, contact your doctor.
Apply hot or cold-water bag on your head. Try to rest in a quiet and dark room. Massage the scalp or head gently. Avoid the consumption of excessive alcohol, as it could make your headache worse. If symptom persists, contact your doctor.
Drink a fruit juice, or consume glucose tablets or gel, soft drinks, honey, or sugary candy. Check your sugar level after 10 minutes. If it's still not improved, take another sugary snack, or drink, and check the blood sugar again. If symptom persists, contact your doctor.
Take ABVIDA D TABLET with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. If symptom persists, contact your doctor.
ABVIDA D TABLET is not recommended for use if you are pregnant or planning to have a baby. Consult your doctor before taking it.
ABVIDA D TABLET is not recommended for use in breastfeeding woman as it is not known if this medicine passes into breast milk. Consult your doctor before taking it.
Do not drive or operate any machines if you feel dizzy after taking ABVIDA D TABLET.
ABVIDA D TABLET should be used with caution in patients with a history of alcohol abuse. Consult your doctor for advice.
ABVIDA D TABLET should be used with caution in patients having moderate or severe kidney disease and in those undergoing dialysis. Consult your doctor before taking it.
ABVIDA D TABLET should be used with caution in patients with liver disease. Consult your doctor before taking it.
Do not take ABVIDA D TABLET if you are allergic to Dapagliflozin, Vildagliptin, or any of the other ingredients of this medicine.
ABVIDA D TABLET should be used with caution in patients suffering from heart failure. Consult your doctor before taking it.
ABVIDA D TABLET is not recommended for use in children and adolescents (below 18 years of age). Consult your child’s doctor for advice.
ABVIDA D TABLET should be used with caution in elderly patients (above 65 years of age). Consult your doctor for advice.
Before taking ABVIDA D TABLET, inform your doctor if you:
A. Drug - Drug interactions:
Before taking ABVIDA D TABLET, inform your doctor if you are taking any of the following medicines:
Overdosage:
If you or anyone else accidentally take too much of ABVIDA D TABLET, consult your doctor immediately or visit the nearby hospital.
Drug | : | Dapagliflozin, Vildagliptin |
Pharmacological Category | : | Dipeptidyl Peptidase 4 (DPP-4) inhibitor |
Therapeutic Indication | : | Type II diabetes mellitus |
Dosage Forms | : | Tablet |
Q: Can ABVIDA D TABLET treatment affect my skin?
A: Not ABVIDA D TABLET, but diabetes has a complication of diabetic skin lesions. You should follow the recommendations for skin and foot care that you are given by your doctor and should pay particular attention to new onset of blisters or ulcers while taking ABVIDA D TABLET. Should these occur, you should immediately consult your doctor.
Q: How long should I take ABVIDA D TABLET?
A: Take ABVIDA D TABLET every day for as long as your doctor advises you. You may have to take this medicine over a long period of time. Your doctor will regularly monitor your condition to ensure that management with ABVIDA D TABLET is having the desired effect.
Q: Does ABVIDA D TABLET cause weight loss?
A: Yes. ABVIDA D TABLET may cause weight loss in some individuals. To avoid weight loss, follow a healthy diet and regular exercise as advised by your physician. However, if the weight loss worries you, consult your doctor.
Q: Can ABVIDA D TABLET cause vaginal infections?
A: Women taking ABVIDA D TABLET may get vaginal yeast infections because of one of its components (Dapagliflozin). If you experience white or yellowish vaginal discharge, vaginal odour or itching while taking ABVIDA D TABLET, consult your doctor immediately.
Q: What should I do if I forgot to take ABVIDA D TABLET?
A: If you forget to take a dose by chance, try to take the next dose of ABVIDA D TABLET as soon as you notice. However, if the time for the next dose is closer, skip the missed dose and do not try to take a double dose.
Q: Can ABVIDA D TABLET make me feel dehydrated?
A: One of the ingredients of ABVIDA D TABLET (Dapagliflozin) can make some people feel dehydrated (loss of body water and salt). If you feel dizzy, faint, lightheaded, or weak, especially when you stand up, see your doctor immediately.
1. KD. Tripathi. Insulin, Oral Anti Diabetic Drugs and Glucagon. Essentials of Medical Pharmacology. Eighth edition. 2013. Page – 298, 301.
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3. PubChem Compound Summary for CID 6918537, Vildagliptin. National Center for Biotechnology Information. PubChem. November 2022. [Accessed on 18th November 2022]. https://pubchem.ncbi.nlm.nih.gov/compound/Galvus#section=Mechanism-of-Action
4. Exemed Pharmaceuticals. TORGLIP D 5/ TORGLIP D 10 (Dapagliflozin + Vildagliptin). Torrent Pharmaceuticals Ltd. [Revised in April 2022]. [Accessed on 18th November 2022]. https://www.torrentian.com/pisheet/Upload/PI_Sheet/3084.pdf
5. AstraZeneca UK Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021]. [Accessed on 18th November 2022]. https://www.medicines.org.uk/emc/files/pil.7607.pdf
6. Pharmadox Healthcare Ltd. Electronic Medicines Compendium (EMC). [Revised in September 2021]. [Accessed on 18th November 2022]. https://www.medicines.org.uk/emc/files/pil.14086.pdf
Written By Srilekha. R, B.Pharm
Last updated on 31 Jan 2024 | 04:40 PM(IST)