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INTRODUCTION ACTIVE COLD P SUSPENSION is a combination of Chlorpheniramine, Paracetamol and Phenylephrine which belongs to the group of medicines called Antihistamines, Analgesics and Nasal decongestants respectively. It is used to relieve the symptoms of allergic rhinitis (hay fever), common...
ACTIVE COLD P SUSPENSION is a combination of Chlorpheniramine, Paracetamol and Phenylephrine which belongs to the group of medicines called Antihistamines, Analgesics and Nasal decongestants respectively. It is used to relieve the symptoms of allergic rhinitis (hay fever), common cold, other upper respiratory allergies, like headache, facial congestion and pressure, nasal congestion, runny nose, sneezing, minor aches and pains, itching of the nose, throat, or eyes, and watery eyes. It can also be used as an adjunct with antibiotics in sinusitis (inflammation of cavities around your nose), tonsillitis (inflammation of tonsils), and otitis media (inflammation inside the middle ear). Hay fever is a seasonal allergy that occurs in response to specific allergens like pollens, present at certain times of the year (spring or fall) and causes more short-term symptoms.
ACTIVE COLD P SUSPENSION is not recommended for use in children (aged less than 2 months). Consult your doctor for advice. Before taking ACTIVE COLD P SUSPENSION, inform your doctor if you have any kidney, liver, heart, thyroid, or lung problems, diabetes, or glaucoma. Consult your doctor for advice. ACTIVE COLD P SUSPENSION should be used with caution in pregnant and breastfeeding women, so consult your doctor before taking it.
The most common side effects of taking ACTIVE COLD P SUSPENSION are vomiting, nausea, allergic reaction, sleepiness, and headache. Contact your doctor if any of the above side effects worsen.
It is used:
ACTIVE COLD P SUSPENSION relieves upper respiratory symptoms where Chlorpheniramine binds to the histamine H1 receptor and blocks its action, resulting in temporary relief of the negative symptoms (runny nose, sneezing, watery and itchy eyes) brought on by histamine. Paracetamol relieves pain by elevation of the pain threshold and reduces fever by acting on the on the heat-regulating centre in your brain. Phenylephrine constricts blood vessels and reduces the blood flow to certain areas, thus decreasing swelling and allowing nasal and respiratory passages to open up.
Take ACTIVE COLD P SUSPENSION as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Stop taking ACTIVE COLD P SUSPENSION and contact your doctor immediately if you experience any of the following side effects:
Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes and alcohol.
Drink ample amount of water. Get adequate rest. Try to be relaxed and stress free. Ask your doctor before taking any medicine for headache.
Take regular sips of a cold drink. Have ginger or peppermint tea. Stick to simple meals. Avoid eating oily or spicy foods. Get adequate rest. Drink lots of fluids, especially water. Do not take any medicine without asking your doctor.
ACTIVE COLD P SUSPENSION should be used in pregnant women only if considered clearly necessary by your doctor. Consult your doctor before taking it.
ACTIVE COLD P SUSPENSION should be used in breastfeeding women only if considered clearly necessary by your doctor. Consult your doctor before taking it.
Do not drive or use any machines during treatment with ACTIVE COLD P SUSPENSION. Consult your doctor for advice.
Avoid consumption of alcohol with ACTIVE COLD P SUSPENSION. It should be used with caution in patients with alcohol dependence. Consult your doctor before taking ACTIVE COLD P SUSPENSION.
ACTIVE COLD P SUSPENSION should be used with caution in patients having kidney dysfunction and urinary retention. Consult your doctor before taking it.
ACTIVE COLD P SUSPENSION is not recommended for use in patients with liver insufficiency, failure or active liver disease. ACTIVE COLD P SUSPENSION should be used with caution in patients with liver dysfunction. Consult your doctor before taking it.
Do not take ACTIVE COLD P SUSPENSION if you are allergic to Chlorpheniramine, Paracetamol, Phenylephrine, or any other ingredients of this medicine.
ACTIVE COLD P SUSPENSION should be used with caution in patients with chronic bronchitis, asthma, bronchiectasis, and cough that lasts long, or that occurs with too much phlegm. Consult your doctor before taking it.
ACTIVE COLD P SUSPENSION is not recommended in patients with severely high blood pressure or any other cardiovascular problems. Consult your doctor before taking it.
ACTIVE COLD P SUSPENSION is not recommended for use in children (aged less than 2 years). Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition. Consult your doctor before taking it.
ACTIVE COLD P SUSPENSION should be used with caution in elderly patients as they may be at a greater risk of getting side effects. Consult your doctor before taking it.
ACTIVE COLD P SUSPENSION is not recommended for use if you have:
Before taking ACTIVE COLD P SUSPENSION, inform your doctor if you:
A. Drug - Drug interactions:
Before taking ACTIVE COLD P SUSPENSION, inform your doctor if you are taking any of the following medicine:
Overdosage:
If you or anyone else accidentally took too much of ACTIVE COLD P SUSPENSION, contact your doctor immediately or visit nearby hospital.
| Drug | : | Chlorpheniramine, Paracetamol, Phenylephrine |
| Pharmacological Category | : | Antihistamine, Antipyretic-Analgesic, Nasal decongestant |
| Therapeutic Indication | : | Symptoms of upper respiratory allergies, Common Cold |
| Dosage Forms | : | Tablet, Syrup, Suspension, Liquid, Drops, Oral Suspension |
Q: Can ACTIVE COLD P SUSPENSION be used on infants?
A: ACTIVE COLD P SUSPENSION is not recommended for use in children (aged less than 2 years). Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition. Consult your doctor before taking it.
Q: What if I forget to take a dose of ACTIVE COLD P SUSPENSION?
A: If you forget to take a dose of ACTIVE COLD P SUSPENSION, take it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not take the medicine twice to make up for a forgotten dose.
Q: Can I stop taking ACTIVE COLD P SUSPENSION?
A: Do not stop taking ACTIVE COLD P SUSPENSION without consulting your doctor. You can do it if you experience any serious side effects with your doctor’s consultation. If you have any more doubts regarding the use of ACTIVE COLD P SUSPENSION, ask your doctor.
Q: Can ACTIVE COLD P SUSPENSION cause dizziness?
A: Dizziness is a common side effect of ACTIVE COLD P SUSPENSION. In such case, lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and tell your doctor if your dizziness does not improve.
Q: What precautions do I need to follow while taking ACTIVE COLD P SUSPENSION?
A: Patients taking ACTIVE COLD P SUSPENSION must inform their doctor about their pre-existing disease conditions like kidney, liver, heart, thyroid, or lung problems, diabetes, or glaucoma.
Q: Can ACTIVE COLD P SUSPENSION be taken during pregnancy?
A: ACTIVE COLD P SUSPENSION should be used in pregnancy only if considered clearly necessary by your doctor. If you are pregnant, think you may be pregnant or are planning to get pregnant, consult your doctor before taking this medicine.
1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Allergic Rhinitis. Pharmacotherapy Handbook. Ninth edition. Page- 813.
2. Kiran, M., Vakharia, M., Pawaskar, L., & Sheikh, S. Efficacy and safety of a fixed dose combination of paracetamol, chlorpheniramine maleate and phenylephrine in treatment of common cold: a phase IV, open-labelled, multi-centric study. International Journal of Basic & Clinical Pharmacology. 2018. [Accessed on 21st June 2022] https://www.ijbcp.com/index.php/ijbcp/article/view/3076
3. PubChem Compound Summary for CID 2725, Chlorpheniramine. National Center for Biotechnology Information. June 2022. [Accessed on 21st June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Chlorpheniramine#section=Mechanism-of-Action
4. Centaur Pharma. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 22nd June 2022] https://www.centaurpharma.com/downloads/Sinarest-Oral-Drops2018.pdf
5. Pharmasynth Formulation Ltd. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 22nd June 2022] https://pharmasynth.in/product/sedoril-kid/
6. Zuventus Healthcare Ltd. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 22nd June 2022] http://www.zuventus.co.in/patient_wise_products_selected.aspx?Medi_Id=219
7. Ticoma Pharmacia. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 22nd June 2022] https://www.jabsbiotech.com/product/paracetamol-phenylephrine-hydrochloride-chlorpheniramine-maleate-syrup#tab-additional_information
8. Wellona Pharma. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 22nd June 2022] https://wellonapharma.com/product/finished/paracetamol-phenyephrine-chlorpheniramine-suspension
9. Comed Chemicals. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 22nd June 2022] https://comedchemicals.com/product?id=22
10. Franco Indian Pharmaceuticals Pvt. Ltd. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 22nd June 2022] http://www.francoindian.com/products/grilinctus-paediatric-syrup.htm
11. Kepler healthcare Pvt. Ltd. Chlorpheniramine + Paracetamol + Phenylephrine. [Accessed on 22nd June 2022] https://keplerhealthcare.com/product/nosier-syrup/
Written By Dr. Janet.C, Pharm.D
Last updated on 11 Feb 2023 | 04:36 PM(IST)