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INTRODUCTION GOLBI SR 450MG TABLET contains Ursodeoxycholic Acid that belongs to the group of medicines called Hepatoprotective agents. It is used to treat primary biliary cirrhosis (damage of bile ducts in liver leading to build up of bile). GOLBI SR 450MG TABLET is also...
GOLBI SR 450MG TABLET contains Ursodeoxycholic Acid that belongs to the group of medicines called Hepatoprotective agents. It is used to treat primary biliary cirrhosis (damage of bile ducts in liver leading to build up of bile).
GOLBI SR 450MG TABLET is also used to dissolve small gallstones which are not visible on X ray (less than 15mm diameter) in patients with a functioning gall bladder. Gall stones are hardened deposits mostly made up of cholesterol that can form in gallbladder and can cause sharp, intense pain in the upper right part of the abdomen.
GOLBI SR 450MG TABLET can also be used for liver disease associated with cystic fibrosis in children aged 6 to less than 18 years. Cystic fibrosis is a diseases affects the cells that produce mucus, sweat and digestive juices and causes these fluids to become thick and sticky resulting in plugged up tubes, ducts and passageways.
During or while the treatment with GOLBI SR 450MG TABLET, your doctor might ask you to get several diagnostic tests done such as liver function test and gall bladder scan.
GOLBI SR 450MG TABLET is not recommended for use in patients having allergy to bile acids, calcified gallstones, inflammation of the gallbladder or the bile ducts, blockage of common bile duct or cystic duct, frequent cramp like pains in upper abdomen, low bile flow in children or improper function of gall bladder. GOLBI SR 450MG TABLET should be used with caution in patients having liver diseases.
GOLBI SR 450MG TABLET should be taken during pregnancy only if clearly advised by the doctor and should be used with caution in breast-feeding women. Ask for your doctor’s advice before taking. GOLBI SR 450MG TABLET can be used in children, adolescents and elderly. Your doctor will decide the correct doe and duration of therapy with GOLBI SR 450MG TABLET for you.
The most common side effects of taking GOLBI SR 450MG TABLET are soft, loose stools or diarrhoea. Consult your doctor if the symptoms worsen or doesn’t improve.
Treats,
GOLBI SR 450MG TABLET helps in reducing raised liver enzyme levels by increasing the bile flow through the liver and protecting liver cells. GOLBI SR 450MG TABLET is concentrated in bile and decreases biliary cholesterol by suppressing the formation of new cholesterol by inhibiting its intestinal absorption. The reduced cholesterol levels lead to gradually solubilization of cholesterol from gallstones, resulting in their dissolution.
Always use GOLBI SR 450MG TABLET exactly as prescribed by your doctor. Take this medicine with or after meals.
For Tablet, Capsule: Swallow GOLBI SR 450MG TABLET with a glass of water or milk. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse GOLBI SR 450MG TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution.
Your doctor will decide the right dose and duration of therapy for you depending upon your age, body weight and severity of disease condition. Continue to take GOLBI SR 450MG TABLET for the stipulated duration prescribed by your doctor to achieve better results. If you feel that the effect of GOLBI SR 450MG TABLET is too strong or too weak for you, please talk to your doctor.
Stop taking GOLBI SR 450MG TABLET and contact your doctor immediately if you experience any of the following side effects:
Diarrhoea:
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Ask for your doctor’s advice if diarrhoea doesn’t improve.
GOLBI SR 450MG TABLET should be used in pregnant women only if considered clearly necessary by the doctor. If you are pregnant or think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking GOLBI SR 450MG TABLET.
GOLBI SR 450MG TABLET should be used with caution in breastfeeding women as it is not known if it passes through breast milk. Consult your doctor if you are breastfeeding or about to start breastfeeding before taking GOLBI SR 450MG TABLET.
GOLBI SR 450MG TABLET has no or negligible effect on driving or using machine.
GOLBI SR 450MG TABLET should be used with caution in patients with liver diseases. Your doctor might advise you for frequent liver examination and tests during the treatment. Consult your doctor before taking the GOLBI SR 450MG TABLET.
Do not take GOLBI SR 450MG TABLET if you are allergic to allergic to Ursodeoxycholic Acid or bile acids or any other components of this medicine.
GOLBI SR 450MG TABLET is not recommended for use if you:
Use in paediatrics:
GOLBI SR 450MG TABLET is not recommended for use in children with biliary atresia (blockage in bile duct) and who have poor bile flow, even after surgery. It can be used in other children. Your doctor will decide the correct dose and duration of GOLBI SR 450MG TABLET for your child depending on his weight, age, and diseases condition. Consult with your child’s doctor before giving it to your child.
Use in geriatrics:
GOLBI SR 450MG TABLET can be used in elderly patients. However, consult with your doctor before taking GOLBI SR 450MG TABLET.
A. Drug-Drug interactions:
Before taking GOLBI SR 450MG TABLET, inform your doctor if you are taking any of the following medicine:
Overdosage:
If you or anyone else takes too much of GOLBI SR 450MG TABLET, consult your doctor immediately or visit the nearby hospital. The symptom of overdosage is diarrhoea.
| Drug | : | Ursodeoxycholic Acid |
| Pharmacological Category | : | Cholagogues and Choleretics |
| Therapeutic Indication | : | Biliary cirrhosis, Gallstones, Liver diseases associated with cystic fibrosis |
| Dosage Forms | : | Tablet, Dispersible tablet, Syrup, Suspension |
Why is GOLBI SR 450MG TABLET prescribed?
GOLBI SR 450MG TABLET is used to treat primary biliary cirrhosis (PBC), to dissolve cholesterol gallstones and to treat liver disease associated with cystic fibrosis in children aged 6 to 18 years.
Do I need to undergo any diagnostic tests before or while getting treated with GOLBI SR 450MG TABLET?
During or while the treatment with GOLBI SR 450MG TABLET, your doctor might ask you to get several diagnostic tests done such as liver function test and gall bladder scan.
Can I stop taking GOLBI SR 450MG TABLET on my own?
Do not stop taking GOLBI SR 450MG TABLET unless advised by your doctor. Your doctor might advise you on how long you should continue to take GOLBI SR 450MG TABLET. From time to time, you will need to consult your doctor to review your treatment and assess your symptoms.
Can GOLBI SR 450MG TABLET cause diarrhoea?
Diarrhoea is the most common side effect of GOLBI SR 450MG TABLET. It may occur as a result of overdose as well. If you do suffer from diarrhoea, make sure you drink enough liquids to replace your fluid and electrolyte balance and stay hydrated. Stop taking GOLBI SR 450MG TABLET and inform your doctor immediately if you have persistent diarrhoea.
What is the best time to take GOLBI SR 450MG TABLET?
Take GOLBI SR 450MG TABLET with or after meals. For tablet, capsule, swallow GOLBI SR 450MG TABLET with a glass of water or milk. Do not crush or chew the medicine. For dispersible tablet, disperse GOLBI SR 450MG TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution. If you feel that the effect of GOLBI SR 450MG TABLET is too strong or too weak for you, please talk to your doctor.
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Written By Dr. Priyanka Goel, BDS
Last updated on 27 Oct 2022 | 01:38 PM(IST)