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INTRODUCTION ANABREZ 1MG TABLET contains Anastrozole, which belongs to the group of medicines called Anti-cancer drugs. It works by lowering the levels of a female sex hormone called oestrogen (responsible for the growth and proliferation of tumour cells in the breast) in women who have underg...
ANABREZ 1MG TABLET contains Anastrozole, which belongs to the group of medicines called Anti-cancer drugs. It works by lowering the levels of a female sex hormone called oestrogen (responsible for the growth and proliferation of tumour cells in the breast) in women who have undergone menopause.
Along with the management, you might have to undergo some lifestyle changes, such as maintaining a healthy weight, exercising, and quitting alcohol. Prior to the management of ANABREZ 1MG TABLET, your doctor might want you to take some diagnostic tests to better evaluate your condition.
Before taking ANABREZ 1MG TABLET, inform your doctor if you have liver or kidney problems, lactose intolerance, or osteoporosis (decreased strength of bones).
If you are pregnant or breastfeeding, you should not take ANABREZ 1MG TABLET without the consultation of your doctor.
ANABREZ 1MG TABLET is not recommended for use in children and adolescents. It should be used with caution with elderly patients.
The most common side effects of taking ANABREZ 1MG TABLET are hot flushes, weakness, pain, stiffness or inflammation in joints, nausea, vomiting, and loss of appetite. Consult your doctor if any of the side effects worsen.
ANABREZ 1MG TABLET works by lowering the levels of a sex hormone called oestrogen in liver, fat, muscle, and breast cells by inhibiting the aromatase enzyme, which converts androgens into oestrogen (which stimulates the growth and proliferation of tumour cells in the breast).
Take ANABREZ 1MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.
Stop taking ANABREZ 1MG TABLET and contact your doctor immediately if you experience any of the following side effects:
Drink a lot of fluids, such as water or fruit juice, to keep yourself hydrated. Do not consume any medicine on your own for managing diarrhea without consulting your doctor. Consult your doctor if the symptoms do not improve.
Drink an ample amount of water. Get adequate rest. Try to be relaxed and stress-free. Apply a pain-relieving balm to your forehead if necessary. Consult your doctor if the symptom does not improve.
Eat when you feel hungry. Eat smaller meals more frequently than usual. Snack only when you're hungry. Eat a nutritious snack that is rich in calories and protein, such as dried fruit and nuts. Consult your doctor if the symptoms do not improve.
Try to rest and relax. Keep a heat pad on the affected area. If the symptom does not improve, contact your doctor.
Take this medicine with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if the symptom does not improve.
ANABREZ 1MG TABLET is not recommended for use by pregnant women. Consult your doctor before taking it.
ANABREZ 1MG TABLET is not recommended for use by breastfeeding women. Consult your doctor before taking it.
Do not drive or operate any machines if you feel weak or sleepy after taking ANABREZ 1MG TABLET.
ANABREZ 1MG TABLET should be taken with caution in patients with kidney problems. Consult your doctor before taking it.
ANABREZ 1MG TABLET should be taken with caution in patients with liver problems. Consult your doctor before taking it.
Do not take ANABREZ 1MG TABLET if you are allergic to Anastrozole or any other ingredients of this medicine.
ANABREZ 1MG TABLET is not recommended for use in children and adolescents. Consult your child’s doctor for advice.
ANABREZ 1MG TABLET should be used with caution with elderly patients. Consult your doctor before taking it.
Before taking ANABREZ 1MG TABLET, inform your doctor if you:
A. Drug-drug interactions:
Overdosage:
If you or anyone else accidentally takes too much of ANABREZ 1MG TABLET, consult your doctor immediately or visit the nearby hospital.
| Drug | : | Anastrozole |
| Pharmacological Category | : | Aromatase Inhibitors |
| Therapeutic Indication | : | To lower the levels of oestrogen in post-menopausal women |
| Dosage Forms | : | Tablet, Capsule |
Q: Does ANABREZ 1MG TABLET affect bone health?
A: Yes, ANABREZ 1MG TABLET acts by lowering the estrogen levels in the body, which is an important hormone to maintain bone health. Due to this, the mineral content of the bones decreases, and they may become less strong and more prone to fracture. Your doctor might ask you to take several tests to better assess and manage your condition.
Q: Can I stop taking ANABREZ 1MG TABLET on my own?
A: No, do not stop taking ANABREZ 1MG TABLET without the advice of your doctor. However, not taking the medicine at the recommended time may increase the risk of your breast cancer recurring.
Q: Is ANABREZ 1MG TABLET a form of chemotherapy?
A: No, ANABREZ 1MG TABLET acts by decreasing the estrogen levels in the body, which is a hormone. This in turn decreases the growth of cancer cells in breasts. ANABREZ 1MG TABLET is hormone therapy.
Q: Who should avoid taking ANABREZ 1MG TABLET?
A: ANABREZ 1MG TABLET is not recommended if you still have menstrual periods, are pregnant or planning to become pregnant, or are allergic to ANABREZ 1MG TABLET. Consult your doctor before taking ANABREZ 1MG TABLET.
Q: What if I forget to take a dose of ANABREZ 1MG TABLET?
A: If you forget to take a dose of ANABREZ 1MG TABLET, just take your next dose as normal. Do not take two doses of ANABREZ 1MG TABLET at the same time to make up for a forgotten dose.
Q: Can alcohol be consumed with ANABREZ 1MG TABLET?
A: It is best to avoid or limit alcohol intake when ANABREZ 1MG TABLET is taken, since alcohol can raise your risk of experiencing side effects from ANABREZ 1MG TABLET such as hot flashes or joint pain.
Q: Should calcium be taken with ANABREZ 1MG TABLET?
A: It is advisable to take calcium and vitamin D supplements while ANABREZ 1MG TABLET is taken since the medicine may cause bone loss as a side effect, which can be monitored by a bone mineral density (BMD) test if done every 1 to 2 years.
Q: Is ANABREZ 1MG TABLET safe to use with children?
A: ANABREZ 1MG TABLET is not recommended for use in children and adolescents under 18 years of age due to a lack of safety and effectiveness. Generally, breast cancer occurs in older women. However, consult your doctor for advice before taking ANABREZ 1MG TABLET.
1. KD. Tripathi. Estrogens, Progestins and Contraceptives. Essentials of medical pharmacology. Seventh edition. 2013. Page – 315.
2. Monica Milani, Gautam Jha, David A. Potter. Anastrozole Use in Early Stage Breast Cancer of Post-Menopausal Women. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. March 2009. [Accessed on 19th April 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753667/
3. William R Miller. Aromatase inhibitors: mechanism of action and role in the treatment of breast cancer. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. August 2003. [Accessed on 19th April 2022] https://pubmed.ncbi.nlm.nih.gov/14513432/
4. ANI Pharmaceuticals, Inc. Astra Zeneca. [Revised in September 2020]. [Accessed on 19th April 2022] https://www.arimidex.com/arimidex-faqs/
5. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in April 2021]. [Accessed on 19th April 2022] https://www.medicines.org.uk/emc/files/pil.6051.pdf
Written By Dr. N. Sai Swaroop, Pharm.D
Last updated on 02 Nov 2023 | 11:11 AM(IST)