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INTRODUCTION KINDTROL CAPSULE contains Calcitriol, which belongs to the group of medicines called Vitamin D analogs. It is used to manage bone disorders caused by calcium deficiencies due to various disease conditions such as renal osteodystrophy, menopausal osteoporosis, hyperparathyroidism,...
KINDTROL CAPSULE contains Calcitriol, which belongs to the group of medicines called Vitamin D analogs. It is used to manage bone disorders caused by calcium deficiencies due to various disease conditions such as renal osteodystrophy, menopausal osteoporosis, hyperparathyroidism, hypocalcaemia, and hypophosphatemia. Your doctor will monitor your calcium and renal function levels to ensure the efficacy of KINDTROL CAPSULE.
Renal osteodystrophy is a complication of chronic kidney disease that weakens bones. It is caused by changes in the levels of minerals and hormones in the blood. The main signs are bone pain and fractures. Menopausal osteoporosis is a condition where the bones start weakening in menopausal women.
Hyperparathyroidism is a condition when parathyroid hormones secrete excess thyroid hormones. Hypocalcemia refers to low levels of calcium in the blood. Hypophosphatemia indicates low levels of phosphorus in the blood.
KINDTROL CAPSULE is not recommended for use in patients with high levels of calcium in the blood (hypercalcaemia), deposits of calcium (metastatic calcification), or high levels of vitamin D.
KINDTROL CAPSULE should be used with caution in patients having difficulties moving due to medical conditions, surgeries, or kidney disease. Avoid consuming foods rich in vitamin D.
KINDTROL CAPSULE should be used with caution in pregnant and breast-feeding women. KINDTROL CAPSULE should be used with caution with elderly patients.
The most common side effect of KINDTROL CAPSULE is high levels of calcium in the blood. Consult your doctor if any side effects worsen or persist for a longer duration.
It is used to manage:
KINDTROL CAPSULE acts on cells in the gastrointestinal tract to increase the production of calcium transport proteins (calbindin-D proteins), which results in increased uptake of calcium from the gut into the body. Calcitriol inhibits parathyroid hormone activity by decreasing parathyroid hormone synthesis and release. It promotes the absorption of dietary calcium from the gastrointestinal tract, increases renal tubular reabsorption of calcium, thus reducing the loss of calcium in the urine, and stimulates the release of calcium from bone. For this, it acts on the specific type of bone cells referred to as osteoblasts. This helps to form healthy bones and reduce bone damage.
Take KINDTROL CAPSULE as directed by your physician. Swallow the whole medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the duration depending on your age, body weight, and disease condition.
Stop taking KINDTROL CAPSULE and contact your doctor if you experience any of the following:
Before taking KINDTROL CAPSULE, tell your doctor if you are pregnant, think you are pregnant, or plan to get pregnant.
KINDTROL CAPSULE is safe for use during breastfeeding. However, your doctor will take blood samples from you and your child to check that there are no unwanted effects.
KINDTROL CAPSULE is not likely to affect your being able to drive or use any tools or machines.
KINDTROL CAPSULE should be used with caution in patients with kidney disease. Consult your doctor before taking it.
There is no proper information regarding the use of this medicine in patients with liver diseases. Consult your doctor before taking it.
Do not take KINDTROL CAPSULE if you are allergic to calcitriol or any other ingredients in this medicine.
KINDTROL CAPSULE should be used with caution in elderly patients aged above 65 years of age. Consult your doctor before taking it.
KINDTROL CAPSULE is not recommended for use if you:
Before taking KINDTROL CAPSULE, inform your doctor if you:
A. Drug-Drug interactions:
Before taking KINDTROL CAPSULE, inform your doctor if you are taking any of the following medicines:
B. Drug-Food interactions :
Avoid consuming foods rich in vitamin D, like milk and cheese, as they may increase calcium levels in the blood.
Overdosage:
If you or anyone else accidentally took more of KINDTROL CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms include high levels of calcium in the blood, loss of appetite, weight loss, nausea, vomiting, headaches, inactivity, and drowsiness.
Drug | : | Calcitriol |
Pharmacological Category | : | Vitamin D analogs |
Therapeutic Indication | : | Renal osteodystrophy, Menopausal osteoporosis, Hyperparathyroidism, Hypocalcaemia, Hypophosphatemia |
Dosage Forms | : | Capsule, Soft gel |
A: Avoid consuming foods rich in calcium, like milk and cheese, as they may increase calcium levels in the blood. Do not replace your diet with foods rich in vitamin D. Drink plenty of water to avoid dehydration. This does not apply if you have kidney problems.
A: No, do not stop taking KINDTROL CAPSULE. Once symptoms are cured, bone disease requires long-term treatment. If you stop taking KINDTROL CAPSULE, it may worsen the existing condition.
A: KINDTROL CAPSULE is used to manage bone disorders caused by calcium deficiencies due to various disease conditions such as renal osteodystrophy, menopausal osteoporosis, hyperparathyroidism, hypocalcaemia, and hypophosphatemia.
A: No, do not take additional doses of KINDTROL CAPSULE to cure the disease condition, as it may cause high levels of calcium in the blood . Symptoms include high levels of calcium in the blood, loss of appetite, weight loss, nausea, vomiting, headaches, inactivity, and drowsiness.
1. KD. Tripathi. Drugs affecting calcium balance. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 341.
2. Lung BE, Mowery ML, Komatsu DEE. Calcitriol November 2021. NIH, National Library of Medicine. National Center for Biotechnology Information. Statpearls. 2023. [Accessed on 10th February 2024] https://www.ncbi.nlm.nih.gov/books/NBK526025/
3. Atnahs Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in September 2020] [Accessed on 10th February 2024] https://www.medicines.org.uk/emc/files/pil.11802.pdf
4. Calcitriol. Daily Med: National Library of Medicine: National Institute of Health. [Revised in August 2019] [Accessed on 10th February 2024] https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=ec93b667-aad2-4e3a-adc6-952f070a0c0a&type=pdf
5. Calcitriol. Alniche Lifesciences Pvt Ltd. [Accessed on 10th February 2024] https://www.alniche.com/product/auxitrol/
Written By Dr. N. Sai Swaroop, Pharm.D
Last updated on 13 Feb 2024 | 05:52 PM(IST)