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INTRODUCTION GEMCAL DS CAPSULE is a combination of Calcitriol, Calcium Carbonate, and Menaquinone, which belongs to the group of medicines called Nutritional Supplements. It is used to manage osteoporosis. Osteoporosis is a condition that cau...
GEMCAL DS CAPSULE is a combination of Calcitriol, Calcium Carbonate, and Menaquinone, which belongs to the group of medicines called Nutritional Supplements. It is used to manage osteoporosis.
Osteoporosis is a condition that causes the thinning and weakening of bones because of the excessive absorption of calcium from the bones. It is characterized by symptoms such as bleeding gums, weak grip strength, brittle fingernails, loss of height, frequent fractures, and neck and back pain.
GEMCAL DS CAPSULE is not recommended for use if you are allergic to calcitriol or calcium. It is also not recommended for use if you have kidney stones, hypercalcaemia (high blood calcium levels), or evidence of vitamin D toxicity.
GEMCAL DS CAPSULE should be used with caution in cases of hepatic insufficiency, nephrotic diseases (a kidney disease causing excess protein in your urine), chronic renal failure, and a high tendency to get kidney stones. GEMCAL DS CAPSULE should also be used with caution in patients undergoing dialysis.
GEMCAL DS CAPSULE should be used with caution by pregnant women only if necessary. GEMCAL DS CAPSULE is not recommended to be used by breastfeeding women. It should be used with caution in children (under 6 years of age) and elderly patients (aged 65 years or older). Consult your doctor before taking it.
The common side effects associated with the use of GEMCAL DS CAPSULE are diarrhea, constipation, an upset stomach, and abdominal pain. Contact your doctor or a nearby hospital if any of the conditions worsen.
GEMCAL DS CAPSULE helps in managing bone weakening, where calcitriol plays a very important role in aiding the absorption of calcium by acting on certain gut cells to increase the production of calcium transport proteins, whereas calcium carbonate acts by directly increasing the calcium stores in the body.
Vitamin K activates the calcium-binding actions of two proteins (the matrix GLA protein and osteocalcin), which helps in enhancing calcium absorption in the body, thereby increasing bone mass and strength.
Take GEMCAL DS CAPSULE as advised by your physician. Swallow the medicine with a glass of water with food. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.
Stop taking GEMCAL DS CAPSULE and contact your doctor if you experience any of the following side effects:
Try to eat more high-fiber foods, such as fresh fruit, vegetables, and cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor about receiving alternate treatments for constipation.
Drink lots of fluids, such as water, to keep yourself hydrated. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptom gets worse.
Try to take GEMCAL DS CAPSULE with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.
GEMCAL DS CAPSULE should be used with caution in pregnant women only if considered necessary. Consult and inform your doctor before taking it.
GEMCAL DS CAPSULE is not recommended for use in breastfeeding women as it passes through the milk. Consult your doctor before taking it.
GEMCAL DS CAPSULE has no or negligible effect on your ability to drive or use machines.
GEMCAL DS CAPSULE is not recommended for use if you have kidney stones. It should be used with caution in patients with nephrotic diseases (a kidney disease causing an excess of protein in your urine), chronic renal failure, and a high tendency to get kidney stones. It should also be used with caution in patients undergoing dialysis. Consult your doctor for advice before taking it.
GEMCAL DS CAPSULE should be used with caution in patients with hepatic insufficiency. Consult your doctor before taking it.
GEMCAL DS CAPSULE is not recommended for use if you are allergic to calcitriol, calcium, or any of the other ingredients of this medicine. Consult your doctor before taking it.
GEMCAL DS CAPSULE should be used with caution in children (below 6 years). Consult your doctor before taking it.
GEMCAL DS CAPSULE should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking it.
GEMCAL DS CAPSULE is not recommended for use if you:
Before taking GEMCAL DS CAPSULE, inform your doctor if you:
A. Drug-Drug Interactions:
Before taking GEMCAL DS CAPSULE, inform your doctor if you are taking any of the following medicines:
Overdosage:
If you or anyone else accidentally takes too much of GEMCAL DS CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are raised blood calcium levels (increased thirst, frequent urination, stomach pain, nausea, bone pain, muscle weakness, confusion, and fatigue), excess calcium in the urine (blood in urine, pain while urinating), hyperphosphatemia (muscle cramps and numbness), nausea, vomiting, constipation, abdominal pain, muscle weakness, tiredness, mental disturbances, lack of appetite, bone pain, kidney problems, irregular heartbeat, irritability, continuing headache, light-headedness, muscle spasms, twitches, and tingling sensation.
| Drug | : | Calcitriol, Calcium Carbonate, and Menaquinone |
| Pharmacological Category | : | Nutritional supplements |
| Therapeutic Indication | : | Osteoporosis |
| Dosage Forms | : | Tablet, Capsule |
A: GEMCAL DS CAPSULE is used to manage osteoporosis, which is a condition that causes thinning and weakening of bones because of excessive absorption of calcium from the bones. It is characterized by symptoms such as bleeding gums, weak grip strength, brittle fingernails, loss of height, frequent fractures, and neck and back pain.
A: If you or anyone else accidentally takes too much GEMCAL DS CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of an overdose are increased blood calcium levels (increased thirst, frequent urination, stomach pain, nausea, bone pain, muscle weakness, confusion, and fatigue), excess calcium in the urine (blood in urine, pain while urinating), hyperphosphatemia (muscle cramps and numbness), nausea, vomiting, constipation, abdominal pain, muscle weakness, tiredness, mental disturbances, lack of appetite, bone pain, kidney problems, an irregular heartbeat, irritability, a continuing headache, lightheadedness, and muscle spasms, twitches, and a tingling sensation are also symptoms.
A: The common side effects associated with the use of GEMCAL DS CAPSULE are diarrhea, constipation, an upset stomach, and abdominal pain. Contact your doctor or a nearby hospital if any of the conditions worsen.
A: GEMCAL DS CAPSULE is not recommended for use if you are allergic to calcitriol or calcium. It is also not recommended for use if you have kidney stones, hypercalcaemia (high blood calcium levels), or evidence of vitamin D toxicity. It is not recommended to be used by breastfeeding women. Consult your doctor before taking it.
A: GEMCAL DS CAPSULE should be used with caution in children (below 6 years) and elderly patients (aged 65 years or older). Your doctor will determine the correct dose and duration for you depending upon your age, body weight, and disease condition.
A: GEMCAL DS CAPSULE helps in managing bone weakening, where calcitriol plays a very important role in aiding the absorption of calcium by acting on certain gut cells to increase the production of calcium transport proteins, whereas calcium carbonate acts by directly increasing the calcium stores in the body. Vitamin K activates the calcium-binding actions of two proteins (the matrix GLA protein and osteocalcin), which helps in enhancing calcium absorption in the body, thereby increasing bone mass and strength.
A: Take GEMCAL DS CAPSULE as advised by your physician. Swallow the medicine with a glass of water and food. Do not crush or chew the medicine. Your doctor will determine the correct dose and duration for you depending upon your age, body weight, and disease condition.
A: If you forgot to take your GEMCAL DS CAPSULE dose, take it as early as possible. Do not double up the dose to make up for the forgotten one. Consult your doctor before taking it.
A: GEMCAL DS CAPSULE is not recommended for use if you have kidney stones. It should be used with caution in patients with nephrotic diseases (a kidney disease causing excess protein in your urine), chronic renal failure, or a high tendency to get kidney stones. It should also be used with caution in patients undergoing dialysis. Consult your doctor for advice before taking it.
A: GEMCAL DS CAPSULE should be used with caution in pregnant women only if clearly necessary. It is not recommended to be used by breastfeeding women. Consult your doctor before taking it.
1. KD. Tripathi. Drugs Affecting Calcium Balance. Essentials of medical pharmacology. Seventh edition. 2013. Page 341.
2. Adriana J. van Ballegooijen, Stefan Pilz, Andreas Tomaschitz, Martin R. Grübler, Nicolas Verheyen. The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. September 2017. [Assessed on 12th February 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613455/
3. Takeda AS, Drammensveien 852. Electronic Medicines Compendium (EMC). [Revised in September 2021] [Assessed on 12th February 2024] https://www.medicines.org.uk/emc/files/pil.12847.pdf
4. Alkem Labs. Gemcal DS. [Assessed on 12th February 2024] https://www.alkemlabs.com/pdf/adverse/GEMCAL%20DS.pdf
5. Dailymed. Calcitriol Capsules (0.25 mcg and 0.5 mcg). [Revised in March 2022] [Assessed on 12th February 2024] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2b48f57a-c023-485d-b846-cab3aaaad486
6. Torrent Pharma. Shelcal-K. [Assessed on 12th February 2024] https://www.torrentpharma.com/pdf/theraputic_areas/Pain_Therapy.pdf
7. Leeford. CETJOINT K2 7. [Assessed on 12th February 2024] https://www.leeford.in/product/489/cetjoint-k2-7
8. Leeford. RECALMIN-D3 STRONG. [Assessed on 12th February 2024] https://www.leeford.in/product/1076/recalmin-d3-strong
Written By Dr. N. Sai Swaroop, Pharm.D
Last updated on 13 Feb 2024 | 05:54 PM(IST)