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INTRODUCTION CALCISPRAY NASAL SPRAY contains Calcitonin which belongs to the group of medicines called Calcium metabolism modifiers. It is used to manage postmenopausal osteoporosis (weak or brittle bones caused during menopause) in women who have crossed 5 years...
CALCISPRAY NASAL SPRAY contains Calcitonin which belongs to the group of medicines called Calcium metabolism modifiers. It is used to manage postmenopausal osteoporosis (weak or brittle bones caused during menopause) in women who have crossed 5 years of menopause when other treatments are not appropriate.
Prior to the treatment, the doctor will perform a skin test to determine whether you are allergic to calcitonin or not. During treatment with CALCISPRAY NASAL SPRAY, your doctor may take several bone-related tests to evaluate improvement in your condition. You may also be prescribed vitamin D or calcium supplements along with CALCISPRAY NASAL SPRAY to improve your disease condition.
Before using CALCISPRAY NASAL SPRAY, inform your doctor if you have low blood calcium levels or any type of cancer as a precaution. Do not use CALCISPRAY NASAL SPRAY without consulting your doctor if you are pregnant or breastfeeding.
The most common side effects of using CALCISPRAY NASAL SPRAY are nasal irritation, headache, back pain, and muscle pain. Consult your doctor if any of these side effects worsen.
It is used among women (greater than 5 years of menopause) to:
CALCISPRAY NASAL SPRAY stops the action of certain bone cells (such as osteoclasts) that destroy the bone mass. This action prevents bone loss and helps build bone mass and density. As a result, it makes your bones stronger and reduces the risk of fracture.
Use CALCISPRAY NASAL SPRAY as advised by your physician. It is for intranasal use only. Prior to use, prime the device by pressing 2-3 puffs in the air. Place the nozzle of the device inside your nostril and gently press the pump to release the spray.
As CALCISPRAY NASAL SPRAY must be stored in the refrigerator, allow it to come to room temperature before use.
Your doctor will decide the suitable dose, number of sprays, and duration of therapy for you depending upon your age, body weight, and health condition. Do not stop using CALCISPRAY NASAL SPRAY without consulting your doctor.
Stop using CALCISPRAY NASAL SPRAY and contact your doctor immediately if you experience any of the following side effects, such as:
Rest and relax. Drink plenty of fluids, such as water or electrolytes, and apply a pain-relieving balm to the head if necessary. Do not consume alcohol. Contact your doctor if the symptom does not improve.
There are no adequate studies to confirm the effects of CALCISPRAY NASAL SPRAY on pregnant women. Therefore, CALCISPRAY NASAL SPRAY should be used in pregnant women only if considered necessary by the physician.
There are no adequate studies to confirm whether CALCISPRAY NASAL SPRAY can pass through breast milk or not. Therefore, CALCISPRAY NASAL SPRAY should be used in breastfeeding women only if considered necessary by the physician.
Do not drive or operate any heavy tools or machines if your abilities are affected by CALCISPRAY NASAL SPRAY.
Talk to your doctor before using CALCISPRAY NASAL SPRAY if you are allergic to calcitonin.
CALCISPRAY NASAL SPRAY is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before using it.
CALCISPRAY NASAL SPRAY should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before using it.
Before using CALCISPRAY NASAL SPRAY, inform your doctor if you have:
A. Drug-Drug interactions:
Before using CALCISPRAY NASAL SPRAY, inform your doctor if you are taking any of the following medicines, such as:
Overdosage:
If you or anyone else accidentally took more CALCISPRAY NASAL SPRAY, contact your doctor or go to the nearest hospital right away.
| Drug | : | Calcitonin |
| Pharmacological Category | : | Calcitonin Receptor Agonist |
| Therapeutic Indication | : | Postmenopausal Osteoporosis |
| Dosage Forms | : | Injection, Nasal Spray |
A: CALCISPRAY NASAL SPRAY is used to manage postmenopausal osteoporosis (weak or brittle bones caused during menopause) in women who have crossed 5 years of menopause when other treatments are not appropriate.
A: CALCISPRAY NASAL SPRAY is for intranasal use only. Prior to use, prime the device by pressing 2-3 puffs in the air. Place the nozzle of the device inside your nostril and gently press the pump to release the spray.
A: The most common side effects of using CALCISPRAY NASAL SPRAY are nasal irritation, headache, back pain, and muscle pain. Consult your doctor if any of these side effects worsen.
A: Yes, elderly patients can use CALCISPRAY NASAL SPRAY after consulting their doctor.
A: Yes. CALCISPRAY NASAL SPRAY helps in managing osteoporosis and helps in gaining back lost bone mass in postmenopausal women.
A: CALCISPRAY NASAL SPRAY stops the action of certain bone cells (such as osteoclasts) that destroy the bone mass. This action prevents bone loss and helps build bone mass and density. As a result, it makes your bones stronger and reduces the risk of fracture.
A: No. Do not stop using CALCISPRAY NASAL SPRAY without consulting your doctor once your symptoms subside, as it may reverse the healed condition. Continue to use CALCISPRAY NASAL SPRAY as long as instructed by your doctor.
A: Yes. CALCISPRAY NASAL SPRAY might cause cancer when used in the long term. Therefore, contact your doctor for advice before using it.
1. KD. Tripathi. Drugs affecting Calcium Balance. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 340.
2. C H Chesnut 3rd 1 , S Silverman, K Andriano, H Genant, A Gimona, S Harris, D Kiel, M LeBoff, M Maricic, P Miller, C Moniz, M Peacock, P Richardson, N Watts, D Baylink. A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study. PROOF Study Group. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. Pubmed.gov. September 2000. [Accessed on 1st February 2024] https://pubmed.ncbi.nlm.nih.gov/10996576/
3. Novartis Pharma Stein AG. U.S. Food & Drug Administration. [Revised in September 2017] [Accessed on 1st February 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020313s036lbl.pdf
4. Novartis Pharmaceutical Corporation. U.S. Food & Drug Administration. [Revised in July 2011] [Accessed on 1st February 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020313s033lbl.pdf
5. Par Pharmaceutical. Calcitonin. [Revised in June 2016] [Accessed on 1st February 2024] https://www.parsterileproducts.com/pdfs/catalog/generic/Calcitonin_PI_20200506.pdf
6. Calcitonin. Apotex Inc. [Revised in November 2017] [Accessed on 1st February 2024] https://www1.apotex.com/products/us/downloads/pil/calc_naso_pil.pdf
7. Apotex Corp. Dailymed. [Revised in January 2021] [Accessed on 1st February 2024] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c82eb602-12e1-692b-d660-f8d5b5736b54&audience=professional
Written By Dr. N. Sai Swaroop, Pharm.D
Last updated on 12 Feb 2024 | 04:34 PM(IST)