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INTRODUCTION ABOUT ALFA SINCAL TABLET ALFA SINCAL TABLET is a combination of Calcitriol, Calcium carbonate, and Zinc sulphate which belongs to the group of medicines called Nutritional supplements. It is used in adults for the management of low blood calcium leve...
ALFA SINCAL TABLET is a combination of Calcitriol, Calcium carbonate, and Zinc sulphate which belongs to the group of medicines called Nutritional supplements. It is used in adults for the management of low blood calcium levels in conditions including chronic renal failure, osteodystrophy (bone pain, joint pain, bone deformation, and fractures due to kidney disease or disturbances in calcium and phosphorus levels), and osteoporosis (bones become weak and brittle as we age).
ALFA SINCAL TABLET is also used to manage hypoparathyroidism (changes to parathyroid glands that may decrease the blood calcium too low), rickets or osteomalacia (softening and weakening of bones in children and adults, respectively, due to a lack of adequate vitamin D), after small bowel resection, and psoriasis (a disease in which skin becomes dry with itchy, scaly patches, most commonly on the knees, elbows, trunk, and scalp).
Avoid taking ALFA SINCAL TABLET within 2 hours of eating foods rich in oxalic acid (Ex. spinach and rhubarb), phosphate (Ex. brain), or phytic acid (Ex. whole cereals). ALFA SINCAL TABLET is not recommended for patients having diseases and/or conditions resulting in hypercalcaemia and/or hypercalciuria (ex. myeloma, bone metastases, primary hyperparathyroidism) and hypervitaminosis D.
ALFA SINCAL TABLET should be used with caution in patients with impaired liver function and kidney problems such as nephrolithiasis, nephrocalcinosis, and renal failure.
ALFA SINCAL TABLET is generally not recommended for use in pregnant women, children, or adolescents unless considered necessary. ALFA SINCAL TABLET should be avoided by breastfeeding women. ALFA SINCAL TABLET should be used with caution with elderly patients.
The common side effects of ALFA SINCAL TABLET are muscle pain, weakness, headache, excessive sleepiness, nausea and vomiting, and dry mouth. If any of these become worse, contact your doctor.
To manage the following conditions in adults:
ALFA SINCAL TABLET is a combination of calcitriol that acts as an active form of vitamin D3 (cholecalciferol) for the absorption of calcium from the stomach and the functioning of calcium in the body. Calcium carbonate works as a nutritional supplement to directly increase the calcium stores within the body, and zinc sulphate counteracts the diminished calcitriol response to arrest bone loss. All these actions together will increase the levels of calcium, which is useful in managing bone disorders and disturbances in the parathyroid glands.
Take ALFA SINCAL TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. The correct dose and duration for you will be decided by your doctor, depending on your age, body weight, and disease condition.
Stop taking ALFA SINCAL TABLET and contact your doctor immediately if you experience any of the following side effects:
Eat smaller and more frequent meals. Eat and drink slowly, and exercise regularly. If you still see no improvement, contact your doctor.
Consume more fiber-rich foods, such as fresh fruits, vegetables, and cereals, in your diet and drink plenty of water. Exercise more regularly. In the event of no improvement, consult your doctor.
Drink more fluids, such as water, fruit juice, or coconut water, to keep yourself hydrated. In the event of no improvement, consult your doctor.
Try to relax and rest yourself. Apply pain balm to the head to ease the pain. Sip on some hot water or ginger tea. If there is no improvement, contact your doctor for advice.
Take this medicine with meals or just after meals. Stick to simple meals and avoid oil-rich or spicy foods. If there is no improvement, consult your doctor.
Take a break to relax. Try to eat and drink slowly, or have smaller, more frequent meals. Place a heating pad on your stomach. If there is no improvement, consult your doctor.
ALFA SINCAL TABLET is generally not recommended for use by pregnant women unless considered necessary. Consult your doctor for advice.
ALFA SINCAL TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor for advice.
ALFA SINCAL TABLET should be used cautiously in patients with kidney problems such as nephrolithiasis, nephrocalcinosis, and renal failure. Consult your doctor for advice.
ALFA SINCAL TABLET should be used with caution in patients with impaired liver function. Consult your doctor for advice.
Do not take ALFA SINCAL TABLET if you are allergic to calcitriol, calcium carbonate, or zinc sulphate.
ALFA SINCAL TABLET is generally not recommended for use in children and adolescents (under 18 years of age). Consult your doctor for advice.
ALFA SINCAL TABLET should be used with caution with elderly patients. Consult your doctor for advice.
ALFA SINCAL TABLET is not recommended for use if you:
A. Drug-Drug interactions:
Before taking ALFA SINCAL TABLET, inform your doctor if you are taking any of the following medicines:
B. Drug-Food interactions:
Avoid taking ALFA SINCAL TABLET within 2 hours of eating foods rich in oxalic acid (Ex. spinach and rhubarb), phosphate (Ex. bran), or phytic acid (Ex. whole cereals).
Overdosage:
If you or anyone else accidentally takes too much of ALFA SINCAL TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of an overdose are nausea, severe vomiting, dehydration, and restlessness.
| Drug | : | Calcitriol, Calcium Carbonate, and Zinc Sulphate |
| Pharmacological Category | : | Vitamin D analogues, and minerals |
| Therapeutic Indication | : | Chronic renal failure, bone disorders, and psoriasis |
| Dosage Forms | : | Tablet, Capsule and Softgel Capsule |
A: ALFA SINCAL TABLET is used in the management of hypocalcaemia, rickets or osteomalacia, hypophosphatemia, hypoparathyroidism, osteodystrophy, and osteoporosis to increase blood calcium. It also maintains the balance of calcium and phosphate metabolism in the body.
A: Yes, ALFA SINCAL TABLET contains calcitriol, which acts as an active form of fat-soluble vitamin D. It helps increase intestinal absorption of calcium and acts as a regulator of calcium and phosphate metabolism.
A: ALFA SINCAL TABLET may cause constipation, nausea, loss of appetite, feeling thirsty, bone pain, stomach pain, frequent urination, and muscle weakness due to its effect on the blood calcium level. If any of these symptoms bother you, consult your doctor immediately.
A: ALFA SINCAL TABLET contains vitamin D and calcium, which help strengthen bones and improve the overall quality of bones. Calcium is also required for the optimal functioning of muscles, the nervous system, and the heart. Hence, taking this medicine is good for your overall health.
A: Always take ALFA SINCAL TABLET as instructed by your doctor and continue to follow any advice about diet recommended by your doctor. Do not stop taking the medicine suddenly because the symptoms may return.
1. KD Tripathi. Drugs affecting calcium balance. Essentials of Medical Pharmacology. Eighth Edition. 2019. Page – 361, 362, 368.
2. Lung BE, Mowery ML, Komatsu DEE. Calcitriol. National Library of Medicine. [Revised in November 2021] [Accessed on 9th February 2024] https://www.ncbi.nlm.nih.gov/books/NBK526025/
3. Ciplamed. Calzem capsules. [Revised in November 2013] [Accessed on 9th February 2024] https://www.ciplamed.com/product-index/calzem-capsules
4. DM pharma. Caldific CZ. [Accessed on 9th February 2024] https://www.dmpharma.co.in/Calcium%20carbonate,%20Zinc%20&%20Calcitriol%20Soft%20Gelatin%20Capsule.html
Written By Dr. N. Sai Swaroop, Pharm.D
Last updated on 15 Feb 2024 | 04:50 PM(IST)