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INTRODUCTION APIQUIS 5 TABLET contains Apixaban, which belongs to the group of medicines called Anticoagulants. It is used to prevent blood clots in patients with an irregular heartbeat (atrial fibrillation). These blood clots can dislodge and travel throughout the body, resulting in systemic...
APIQUIS 5 TABLET contains Apixaban, which belongs to the group of medicines called Anticoagulants. It is used to prevent blood clots in patients with an irregular heartbeat (atrial fibrillation). These blood clots can dislodge and travel throughout the body, resulting in systemic embolism and stroke.
APIQUIS 5 TABLET also helps in the treatment of blood clots in the legs (deep vein thrombosis) and the veins of the lungs (pulmonary embolism) and in the prevention of their recurrence in either legs or lungs.
APIQUIS 5 TABLET should be taken with caution in patients who have liver or kidney disease. APIQUIS 5 TABLET is contraindicated in patients who have active bleeding or have a disease that can lead to active bleeding, such as an active ulcer or a recent bleed in the brain.
APIQUIS 5 TABLET should be used with caution during pregnancy or breastfeeding. APIQUIS 5 TABLET is not recommended for use by children and adolescents (under the age of 18). APIQUIS 5 TABLET should be used with caution in elderly patients over the age of 80.
The most common side effects of taking APIQUIS 5 TABLET are bleeding (eyes, nose, gums, urine, rectum, stomach or bowel), bruising or swelling, anaemia, low blood pressure and a quickened heart rate. If any of these symptoms worsen, contact your doctor immediately.
APIQUIS 5 TABLET helps to prevent the formation of blood clots by acting on the blood clotting mechanism of the body. It blocks clotting factor Xa which is an essential factor in the clotting mechanism.
Take APIQUIS 5 TABLET as advised by your physician. Swallow the medicine with a glass of water. If you have difficulty swallowing the tablet as a whole, talk to your doctor about other ways to take APIQUIS 5 TABLET. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
Stop taking APIQUIS 5 TABLET and contact your doctor immediately if you experience any of the following side effects:
Nausea:
Take this medicine with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods.
The effects of APIQUIS 5 TABLET on pregnancy and the unborn child are not known, hence it is not recommended to take it during pregnancy. Consult your doctor before taking it.
It is not known if APIQUIS 5 TABLET passes into human breast milk. Consult your doctor before taking this medicine while breastfeeding.
APIQUIS 5 TABLET does not impair the ability to drive or use machines. Consult your doctor.
APIQUIS 5 TABLET should be taken with caution in patients with severe kidney disease or who are on dialysis. Consult your doctor before taking it.
APIQUIS 5 TABLET is not recommended for use in patients having liver diseases such as hepatic coagulopathy. It should be used with caution in patients with liver problems or a history of liver problems. Consult your doctor before taking it.
Do not take APIQUIS 5 TABLET if you are allergic to Apixaban.
APIQUIS 5 TABLET should be taken with caution in patients with prosthetic heart valves. Consult your doctor before taking it.
Before taking APIQUIS 5 TABLET, inform your doctor if you:
Use in pediatrics:
Use in geriatrics:
A. Drug–Drug Interactions:
Overdosage:
If you or anyone else accidentally take too much of APIQUIS 5 TABLET, consult your doctor immediately or visit the nearby hospital. Overdose of APIQUIS 5 TABLET can result in increased bleeding.
| Drug | : | Apixaban |
| Pharmacological Category | : | Anti-coagulants |
| Therapeutic Indication | : | Prevention of blood clots in atrial fibrillation, Deep vein thrombosis, Pulmonary embolism |
| Dosage Forms | : | Tablet |
Is APIQUIS 5 TABLET a blood thinner?
Yes. [GBKEYWORD] is a blood thinner, also called an anticoagulant. It prevents blood clot formation and makes it easier for the blood to flow through the body. APIQUIS 5 TABLET blocks an essential factor of the clotting mechanism, thereby making it easy for the blood to flow.
What precautions should I take while taking APIQUIS 5 TABLET?
Patients taking APIQUIS 5 TABLET should inform their doctor about their pre-existing liver, heart or kidney disease. As APIQUIS 5 TABLET is an anti-coagulant and helps in the prevention of blood clot formation, it is important to tell your doctor about any bleeding disorder or any active condition that can cause a bleed. Consult your doctor before taking it.
What if I forget to take a dose of APIQUIS 5 TABLET?
Take the dose as soon as you remember, then take the next dose of APIQUIS 5 TABLET at the usual time and then continue as normal. Consult your doctor once.
Is APIQUIS 5 TABLET safe during pregnancy and breastfeeding?
No, APIQUIS 5 TABLET is not recommended for use during pregnancy and breastfeeding. If you are pregnant, breastfeeding or planning to have a baby, consult your doctor before taking APIQUIS 5 TABLET. If you become pregnant while taking APIQUIS 5 TABLET, contact your doctor immediately.
What is APIQUIS 5 TABLET used for?
APIQUIS 5 TABLET is used to prevent blood clots in patients with an irregular heartbeat (atrial fibrillation). These blood clots have the potential to dislodge and travel throughout the body, resulting in systemic embolism and stroke.APIQUIS 5 TABLET also helps in the treatment of blood clots in the legs (deep vein thrombosis) and the veins of the lungs (pulmonary embolism) and in the prevention of their recurrence in either legs or lungs.
What are the side effects of taking APIQUIS 5 TABLET?
The most common side effects of taking APIQUIS 5 TABLET are bleeding (eyes, nose, gums, urine, rectum, stomach or bowel), tiredness or paleness due to anaemia, low blood pressure and nausea. Consult your doctor if any of these symptoms get worse.
What foods should I avoid while taking APIQUIS 5 TABLET?
Avoid consuming grapefruits or juices as it impacts the effects of APIQUIS 5 TABLET, which may lead to bleeding. To prevent such complications, consult your doctor before taking APIQUIS 5 TABLET.
1. Joseph T. DiPiro, Robert L. Talbert, Cardiovascular Diseases, Pharmacotherapy: A Pathophysiologic Approach, Eighth Edition. 2011. Page – 324.
2. Joseph P. Broderick, Jordan B. Bonomo, Brett M. Kissela, Jane C. Khoury, Charles J. Moomaw, Kathleen Alwell, Daniel Woo, Matthew L. Flaherty, Pooja Khatri, Opeolu Adeoye, Simona Ferioli, Dawn O. Kleindorfer. Withdrawal of Antithrombotic Agents and Its Impact on Ischemic Stroke Occurrence. NIH. National Library of Medicine. National Center for Biotechnology Information. PubMed Central. June 2011. [Accessed on 20th April 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166233/
3. Catalent Anagni S.R.L. Electronic Medicines Compendium (EMC). [Revised in September 2021] [Accessed on 20th April 2022]. https://www.medicines.org.uk/emc/files/pil.2878.pdf
4. Bristol-Myers Squibb Company, Pfizer Inc. Bristol Myers Squib. [Revised in September 2021] [Accessed on 20th April 2022]. https://packageinserts.bms.com/pi/pi_eliquis.pdf
Written By Dr. Dhivakaran R, BDS
Last updated on 25 Nov 2022 | 03:08 PM(IST)