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INTRODUCTION ANZIOLET A 75MG TABLET is a combination of Aspirin and Clopidogrel which belongs to the group of medicines called Antiplatelets. ANZIOLET A 75MG TABLET is used in the prevention of early and long-term atherothrombotic events such as myocardial infarction (also known as heart attac...
ANZIOLET A 75MG TABLET is a combination of Aspirin and Clopidogrel which belongs to the group of medicines called Antiplatelets. ANZIOLET A 75MG TABLET is used in the prevention of early and long-term atherothrombotic events such as myocardial infarction (also known as heart attack), stroke (reduced blood supply to brain leading to brain death), cardiovascular death or refractory ischemia (chest pain due to inadequate blood supply to the heart) in patients having acute coronary syndrome with or without cardiac revascularization (including surgical or PCI, with or without stent insertion).
Acute coronary syndrome is a heart condition caused by plaque rupture or clot formation in the coronary arteries. Symptoms include heart attack, chest pressure or pain while at rest, shortness of breath and sweating.
Along treatment with ANZIOLET A 75MG TABLET follow a healthy low-fat diet as advised by doctor to achieve better results. Avoid drinking alcohol during treatment with ANZIOLET A 75MG TABLET, as it could increase the risk of bleeding in the gastrointestinal tract.
Do not stop taking ANZIOLET A 75MG TABLET abruptly without consulting your doctor because premature discontinuation of this medicine may increase the risk of cardiovascular events. ANZIOLET A 75MG TABLET is not recommended for use in patients having severe liver, kidney or lung disease.
ANZIOLET A 75MG TABLET is generally not recommended for use in pregnant or breastfeeding women and in children (below 18 years). Consult your doctor for an alternative therapy.
The most common side effects of taking ANZIOLET A 75MG TABLET are diarrhea, nausea, stomach pain and indigestion. Contact your doctor if any of the symptoms worsen.
ANZIOLET A 75MG TABLET reduces the risk of heart problems, where clopidogrel acts by irreversibly inhibiting platelet aggregation in the coronary arteries and aspirin acts by blocking an enzyme called cyclo-oxygenase 1 which is believed to be responsible for catalyzing the synthesis of platelets, thus leading to the prevention of fatal cardiac outcomes.
Take ANZIOLET A 75MG TABLET as advised by your physician. Swallow ANZIOLET A 75MG TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Stop taking ANZIOLET A 75MG TABLET and contact your doctor immediately if you experience the following side effects:
Nausea and vomiting:
Try to take ANZIOLET A 75MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom did not improve.
Diarrhea:
Drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom did not improve.
Headache:
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.
Flatulence:
Eat smaller and frequent meals. Eat and drink slowly and exercise regularly. Consult your doctor if the symptom did not improve.
Constipation :
Eat fiber rich foods such as fresh fruits, vegetables and cereals and drink plenty of water. Try to exercise more regularly. Consult your doctor if the symptom did not improve on its own.
Indigestion:
Eat only when you are hungry. Try to eat smaller portions at a time. Always try to have a nutritious snack that is high in calories and protein, such as dried fruit and nuts. Consult your doctor if the symptom did not improve.
ANZIOLET A 75MG TABLET is not recommended for use during pregnancy. Consult your doctor before taking ANZIOLET A 75MG TABLET.
ANZIOLET A 75MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking ANZIOLET A 75MG TABLET.
Do not drive or operate any heavy tools or machines if your ability is affected by ANZIOLET A 75MG TABLET.
Avoid consumption of alcohol while taking ANZIOLET A 75MG TABLET as it could increase the risk of gastrointestinal bleeding. Consult your doctor before taking ANZIOLET A 75MG TABLET.
ANZIOLET A 75MG TABLET is not recommended for use in patients having severe kidney disease and should be used with caution in patients with kidney disease. Consult your doctor before taking ANZIOLET A 75MG TABLET.
ANZIOLET A 75MG TABLET is not recommended for use in patients having severe liver disease and it should be used with caution in patients with liver disease. Consult your doctor before taking ANZIOLET A 75MG TABLET.
Do not take ANZIOLET A 75MG TABLET if you are allergic to Aspirin, Clopidogrel or any other non-steroidal anti-inflammatory drugs (Ex. ibuprofen, celecoxib, etoricoxib).
ANZIOLET A 75MG TABLET is not recommended for use in patients having respiratory conditions such as asthma, nasal discharge (runny nose) or polyps (a type of growth in the nose). Consult your doctor before taking ANZIOLET A 75MG TABLET.
ANZIOLET A 75MG TABLET is not recommended for use if you:
Before taking ANZIOLET A 75MG TABLET, inform your physician if you:
Use in pediatrics:
ANZIOLET A 75MG TABLET is not recommended for use in children and adolescents (under 18 years of age). Consult your doctor for advice.
Use in geriatrics:
ANZIOLET A 75MG TABLET should be used with caution in elderly patients (aged 65 years and above). because of increased risk of gastro-intestinal bleeding and perforation when used for prolonged duration (if prolonged therapy is essential, patients should be reviewed regularly). Consult your doctor before taking ANZIOLET A 75MG TABLET.
A. Drug-Drug interactions:
Before taking ANZIOLET A 75MG TABLET inform to your doctor, if you are taking any of these medicines:
Overdosage:
If you or anyone else take too much of ANZIOLET A 75MG TABLET, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms of ANZIOLET A 75MG TABLET might include increased bleeding, confusion, disorientation, coma, convulsions, vomiting, tinnitus (ringing in the ears), vertigo (spinning sensation), sweating, warm extremities with bounding pulses, increased respiratory rate, hyperventilation, low blood sugar levels, low potassium and platelets levels in blood, increased body temperature, kidney failure, respiratory alkalosis, metabolic acidosis and pulmonary edema (non-cardiac related).
| Drug | : | Aspirin, Clopidogerl |
| Pharmacological Category | : | Antiplatelets |
| Therapeutic Indication | : | Myocardial infarction, Stroke, Cardiac death, Angina |
| Dosage Forms | : | Tablet, Capsule |
Can ANZIOLET A 75MG TABLET be taken at night?
Always take ANZIOLET A 75MG TABLET as advised by your physician. Your doctor will prescribe a suitable dose, frequency and time for you depending upon your age and existing disease condition. Before taking ANZIOLET A 75MG TABLET consult your doctor for more information regarding the direction of use.
Can I consume alcohol while taking ANZIOLET A 75MG TABLET?
No. Avoid consumption of alcohol while taking ANZIOLET A 75MG TABLET as it could aggravate your existing disease condition and increase the risk of bleeding. Before taking ANZIOLET A 75MG TABLET inform your doctor if you are alcoholic.
Can I take paracetamol along with ANZIOLET A 75MG TABLET?
Avoid concomitant use of non-steroidal anti-inflammatory drugs (NSAIDs) like paracetamol or ibuprofen while taking ANZIOLET A 75MG TABLET, because it may increase the risk of gastro-intestinal bleeding. Consult your doctor for an alternative pain relief medicine which can be used with ANZIOLET A 75MG TABLET.
Can ANZIOLET A 75MG TABLET be used in elderly patients?
Yes. ANZIOLET A 75MG TABLET can be used in elderly patients. It should be used with caution in elderly patients (aged 65 years and above) because of increased risk of gastro-intestinal bleeding and perforation when used for prolonged duration (if prolonged therapy is essential, patients should be reviewed regularly). Consult your doctor before taking ANZIOLET A 75MG TABLET.
Can ANZIOLET A 75MG TABLET be used in pregnancy?
No. ANZIOLET A 75MG TABLET is strictly not recommended for use during pregnancy. If you are pregnant or suspect that you are pregnant, you should inform your doctor before taking ANZIOLET A 75MG TABLET.
What to do If I forget to take ANZIOLET A 75MG TABLET?
You should take ANZIOLET A 75MG TABLET immediately when you remember. If it is time for your next dose of ANZIOLET A 75MG TABLET skip the dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.
1. KD. Tripathi. Drugs Affecting Coagulation, Bleeding and Thrombosis. Essentials of medical pharmacology. Seventh edition. 2013. Page – 629-633
2. Jeffery I. Weitz. Blood coagulation and Anticoagulant, Fibrinolytic and Antiplatelet Drugs. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 868-870
3. Gerald G. Briggs and Roger K. Freeman. C. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 888-891 & 288-29
4. Nai-Fang Chi, Chi-Pang Wen, Chung-Hsiang Liu, Jie-Yuan Li, Jiann-Shing Jeng, Chih-Hung Chen, Li-Ming Lien, Ching-Huang Lin, Yu Sun, Wei-Lun Chang, Chaur-Jong Hu, Chung Y. Hsu on behalf of and Taiwan Stroke Registry Investigators. Comparison Between Aspirin and Clopidogrel in Secondary Stroke Prevention Based on Real-World Data. Journal of American heart association. September 2018. [Accessed on 4th October 2021] https://www.ahajournals.org/doi/10.1161/JAHA.118.009856
5. S. Claiborne Johnston, J. Donald Easton, Mary Farrant, William Barsan, Robin A. Conwit, Jordan J. Elm, Anthony S. Kim, Anne S. Lindblad and Yuko Y. Palesch. Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA. The New England journal of Medicine. [Revised in July 2018]. [Accessed on 4th October 2021] https://www.nejm.org/doi/full/10.1056/nejmoa1800410
6. Shereif H. Rezkalla and Michele Benz. Antiplatelet Therapy from Clinical Trials to Clinical Practice. NCBI; PMC US National Library of Medicine, National Institute of Health. April 2003. [Accessed on 4th October 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1069031/
7. Torrent Pharmaceuticals. Deplatt A. Torrentian.com. [Revised in July 2019]. [Accessed on 4th October 2021] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2003.pdf
8. Cipla Ltd. Clopivas-AP Tablets (Clopidogrel + Aspirin). Ciplamed. [Revised in April 2017]. [Accessed on 4th October 2021] https://www.ciplamed.com/content/clopivas-ap-tablets
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 26 Oct 2022 | 02:39 PM(IST)