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INTRODUCTION DEFCORT TM CAPSULE is a combination of Deflazacort and Tamsulosin which belongs to the group of medicines called Corticosteroids and Alpha-blockers respectively. It is used in the treatment of kidney stone by facilitating easy urination. Kidney stones are abno...
DEFCORT TM CAPSULE is a combination of Deflazacort and Tamsulosin which belongs to the group of medicines called Corticosteroids and Alpha-blockers respectively. It is used in the treatment of kidney stone by facilitating easy urination.
Kidney stones are abnormal hard deposits formed from minerals and salts inside the kidney due to some underlying medical condition or certain medications. It is characterised by severe sharp pain in the either side of the lower back, blood in urine, vague stomach-ache, fever, chills or cloudy urine.
Do not drink grapefruit juice while taking DEFCORT TM CAPSULE. Avoid taking this medicine, if you are allergic to deflazacort or tamsulosin and have severe liver infection, serious eye infection, duchenne muscular dystrophy, dizziness (while getting up) or micturition syncope (discomfort while urination).
Before taking DEFCORT TM CAPSULE, inform your doctor if you have high blood pressure, osteoporosis (weak bones), kidney or heart diseases.
DEFCORT TM CAPSULE is not recommended for use in pregnant and breast-feeding women since it is used only in men. It is not recommended for use in children and adolescents (aged below 18 years). Also, it is used with caution in elderly patients.
The most common side effects of taking DEFCORT TM CAPSULE are dizziness, difficulties in ejaculation, increased appetite, frequent urination, nausea and stomach pain. Consult your doctor if any of the side effect gets worse.
DEFCORT TM CAPSULE helps in treating kidney stone and facilitates easy urination where deflazacort blocks the production of certain chemical messengers in the body that cause inflammation and enhances the muscle strength as well as functioning and tamsulosin binds selectively and competitively to certain receptors, causing muscle relaxation around the bladder exit and prostate gland, thereby allowing easy passage of urine.
Take DEFCORT TM CAPSULE as advised by your physician. Swallow the medicine with the glass of water. Do not crush or chew the medicine. Take this medicine after breakfast or after the first daily meal. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Stop taking DEFCORT TM CAPSULE and contact your doctor if you experience any of the following side effects:
Dizziness:
DEFCORT TM CAPSULE may cause dizziness which can be managed by lying down until the dizziness passes and get up slowly. Do not bend down suddenly. Get a lot of rest. Walk slowly and carefully. Take plenty of fluids. Avoid drinking alcohol or smoking. Consult your doctor if the symptom persists for long or gets worsened.
Diarrhoea:
Drink lot of fluids such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to treat diarrhoea and consult your doctor if the symptom gets worse.
Constipation:
Try to eat more high-fibre foods such as fresh fruit, vegetables, cereals and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate treatments for constipation.
Nausea and vomiting:
Try to take DEFCORT TM CAPSULE with or just after a meal or a snack. Stick to simple meals. Avoid eating oil rich or spicy food. Consult your doctor if the symptom gets worse.
DEFCORT TM CAPSULE is not recommended for use in pregnant women since it is used only in men.
DEFCORT TM CAPSULE is not recommended for use in breastfeeding women since it is used only in men.
DEFCORT TM CAPSULE should be used with caution while driving or operating machines since it might cause dizziness. Consult your doctor before taking DEFCORT TM CAPSULE.
Avoid consumption of alcohol while taking DEFCORT TM CAPSULE since it may alter the effect of this medicine.
DEFCORT TM CAPSULE should be used with caution in patients with severe renal impairment. Consult your doctor for advice before taking DEFCORT TM CAPSULE.
DEFCORT TM CAPSULE is not recommended for use in patients with severe liver infection. Consult your doctor before taking DEFCORT TM CAPSULE.
DEFCORT TM CAPSULE is not recommended for use if you are allergic to deflazacort, tamsulosin, or any other ingredients of this medicine.
DEFCORT TM CAPSULE should be used with caution in patients with heart disease such as congestive heart disease (inability of heart to pump sufficient blood), a recent myocardial infarction (blockage of blood flow to heart). Consult your doctor before taking DEFCORT TM CAPSULE.
DEFCORT TM CAPSULE is not recommended for use if you:
Before taking DEFCORT TM CAPSULE, inform your doctor if you:
Use in Paediatrics:
DEFCORT TM CAPSULE is not recommended for use in children and adolescents (aged below 18 years). Consult your child’s doctor for advice.
Use in Geriatrics:
DEFCORT TM CAPSULE should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking DEFCORT TM CAPSULE.
A. Drug-Drug Interactions:
Before taking DEFCORT TM CAPSULE, inform your doctor, if you are taking any of the following medicines:
B. Drug-Food Interactions:
Avoid drinking grapefruit juice while taking this medicine.
Overdosage:
If you or anyone else accidentally takes too much of DEFCORT TM CAPSULE, consult your doctor immediately or visit the nearby hospital. Overdosage symptom of DEFCORT TM CAPSULE is low blood pressure.
| Drug | : | Deflazacort, Tamsulosin |
| Pharmacological Category | : | Corticosteroids, Alpha-blockers |
| Therapeutic Indication | : | Kidney stones |
| Dosage Forms | : | Capsule, Tablet |
What is DEFCORT TM CAPSULE used for?
DEFCORT TM CAPSULE is used in the treatment of kidney stone which works by relaxing the muscle around the bladder exit and prostate gland that results in easy urination or free flow of urine.
What happens if you take more DEFCORT TM CAPSULE than your required dose?
If you or anyone else accidentally takes too much of DEFCORT TM CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are signs of low blood pressure such as light headedness, dizziness or blurred vision.
Who should avoid taking DEFCORT TM CAPSULE?
DEFCORT TM CAPSULE is not recommended for use if you have a history of angioedema (swelling due to allergic reaction) after using of certain drugs, feel dizziness when you sit up or stand up from the lying position, suffer from micturition syncope (malaise or discomfort during or after urinating).
Is DEFCORT TM CAPSULE safe to use in children?
DEFCORT TM CAPSULE is not recommended for use in children and adolescents (aged below 18 years) because tamsulosin (one of the drugs in this medicine) does not work in this population. Consult your doctor before taking DEFCORT TM CAPSULE.
Does DEFCORT TM CAPSULE make you pee more at night?
No, DEFCORT TM CAPSULE does not make you pee more at night. On contrary to this, tamsulosin (one of the drugs in this medicine) reduces night-time urine production in patients with nocturnal polyuria (disorder causing excess urine production in the night-time). Consult your doctor before taking DEFCORT TM CAPSULE.
What if I forget to take DEFCORT TM CAPSULE dose?
If you have forgotten to take DEFCORT TM CAPSULE at the scheduled time, take it anytime later during the day. If you realize this fact only on the next day, continue with the usual dosage scheme. Do not take a double dose to make up for a forgotten dose. Consult your doctor before taking DEFCORT TM CAPSULE.
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2. Yoshiyuki Kojima, Shoichi Sasaki, Makoto Imura, Yasue Kubota, Yutaro Hayashi, Kenjiro Kohri. Tamsulosin reduces nighttime urine production in benign prostatic hyperplasia patients with nocturnal polyuria: a prospective open-label long-term study using frequency-volume chart. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. October 2011. [Assessed on 28th June 2022] https://pubmed.ncbi.nlm.nih.gov/22038792/
3. Pawel Pasko, Tomasz Rodacki, Renata Domagala-Rodacka, Danuta Owczarek. Interactions between medications employed in treating benign prostatic hyperplasia and food - A short review. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. August 2016. [Assessed on 28th June 2022] https://pubmed.ncbi.nlm.nih.gov/27551761/
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5. Marathon Pharmaceuticals, LLC. Food and Drug Administration (FDA). [Revised in February 2017] [Accessed on 28th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/208684s000,208685s000lbl.pdf
6. Clinical Pharmacology and Biopharmaceutics. Food and Drug Administration (FDA). [Revised in April 2016] [Accessed on 28th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/nda/2017/208684,208685Orig1s000ClinPharmR.pdf
7. Olcare Laboratories Pvt. Ltd. Defolt - TM Tablets (Deflazacort + Tamsulosin). [Accessed on 28th June 2022] https://m.olcarelaboratories.com/defolt-tm-tablets-6765246.html
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 19 Dec 2022 | 05:26 PM(IST)