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INTRODUCTION BEGROEASE S 50 TABLET is a combination of Mirabegron and Solifenacin which belongs to the group of medicines called Urinary antispasmodics. It is used to treat the signs of overactive bladder (such as sudden urge to pass urine, increased frequency of passing urine, unable to contr...
BEGROEASE S 50 TABLET is a combination of Mirabegron and Solifenacin which belongs to the group of medicines called Urinary antispasmodics. It is used to treat the signs of overactive bladder (such as sudden urge to pass urine, increased frequency of passing urine, unable to control urine or wetting yourself because you couldn’t go the bathroom).
BEGROEASE S 50 TABLET reduces the activity of an overactive bladder and enables you to wait longer before having to go to the bathroom. Try to take BEGROEASE S 50 TABLET at the same time each day to achieve maximum benefits. It can be taken with or without meals.
Before taking BEGROEASE S 50 TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any other problems in the bladder that obstructs urine flow or if you have glaucoma, constipation, stomach problems (such as tear or block in the gut), muscle weakness or urinary tract infections as a precaution.
BEGROEASE S 50 TABLET is not recommended for use in patients who are not able to pass urine (urinary retention) and in patients with severe bowel problems (such as toxic megacolon). It is not suitable for use in pregnant or breastfeeding women and in children aged below 18 years.
The most common side effects of taking BEGROEASE S 50 TABLET are dry mouth, blurred vision, constipation, nausea, abdominal fullness, stomach pain, burping, heartburn, headache and dizziness. Consult your doctor if any of these side effect worsens.
BEGROEASE S 50 TABLET is a urinary muscle relaxant medicine. It relaxes the smooth muscles surrounding the bladder. This helps your bladder to hold more volume of urine and can control urine flow. As a result, it reduces signs of overactive bladder and enables you to wait longer before having to go to the bathroom.
Take BEGROEASE S 50 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. BEGROEASE S 50 TABLET can be taken with or without food.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Stop taking BEGROEASE S 50 TABLET and contact your doctor immediately if you experience any of the following side effects:
Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Take BEGROEASE S 50 TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.
Close your eyes and relax. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
BEGROEASE S 50 TABLET is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it.
BEGROEASE S 50 TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Therefore, consult your doctor before taking it.
Do not drive or operate any machines if you experience sleepiness, tiredness or blurred vision after taking BEGROEASE S 50 TABLET.
BEGROEASE S 50 TABLET is not recommended for use in patients with moderate to severe kidney problems (including in those who undergo dialysis). It should be used with caution in patients with other mild kidney problems. Therefore, consult your doctor before taking it.
BEGROEASE S 50 TABLET is not recommended for use in patients with moderate to severe liver problems. It should be used with caution in patients with other mild liver problems. Therefore, consult your doctor before taking it.
Do not take BEGROEASE S 50 TABLET if you are allergic to Solifenacin or Mirabegron.
BEGROEASE S 50 TABLET is not recommended for use in patients with uncontrolled high blood pressure. It should be used with caution in patients with heart problems (such as heart failure or abnormal heart rhythm). Therefore, consult your doctor before taking it.
BEGROEASE S 50 TABLET is not recommended for use if you:
Before taking BEGROEASE S 50 TABLET, inform your doctor if you:
Use in Pediatrics:
BEGROEASE S 50 TABLET is not recommended for use in children and adolescents (aged below 18 years of age). Therefore, consult your doctor before taking it.
Use in Geriatrics:
BEGROEASE S 50 TABLET should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
A. Drug – Drug Interaction:
Before taking BEGROEASE S 50 TABLET, inform your doctor if you are taking any of the following medicines such as:
B. Drug – Food Interactions:
BEGROEASE S 50 TABLET can be taken with or without food.
Overdosage:
If you or anyone else accidentally took more BEGROEASE S 50 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are headache, dry mouth, dizziness, drowsiness, blurred vision, hallucinations, over-excitability, seizures, difficulty in breathing, increased heart rate, increased blood pressure, accumulation of urine in the bladder and dilated pupils.
| Drug | : | Mirabegron, Solifenacin |
| Pharmacological Category | : | Beta 3-adrenoceptor agonist, Muscarinic Receptor Antagonists |
| Therapeutic Indication | : | Overactive bladder |
| Dosage Forms | : | Tablet, Combi pack, Combi kit |
Q: Will the use of BEGROEASE S 50 TABLET controls urination?
A: Yes. BEGROEASE S 50 TABLET helps your bladder to hold more volume of urine and controls urine flow. It reduces the activity of an overactive bladder and enables you to wait longer before having to go to the bathroom.
Q: What are the side effects of BEGROEASE S 50 TABLET?
A: The most common side effects of taking BEGROEASE S 50 TABLET are dry mouth, blurred vision, headache, dizziness, constipation, nausea, abdominal fullness, stomach pain, burping, heartburn and stomach discomfort. Inform your doctor if any of the above side effects worsen.
Q: Can BEGROEASE S 50 TABLET affect blood pressure?
A: Yes. BEGROEASE S 50 TABLET may raise blood pressure in some individuals. Therefore, it should be used with caution in patients with history of hypertension.
Q: What happens if you stop taking BEGROEASE S 50 TABLET?
A: Do not stop taking BEGROEASE S 50 TABLET without consulting your doctor as it may make your symptoms reappear. Take BEGROEASE S 50 TABLET for the stipulated duration advised by your doctor to achieve maximum benefits.
Q: How does BEGROEASE S 50 TABLET help in overactive bladder?
A: BEGROEASE S 50 TABLET helps your bladder to hold more volume of urine and controls urine flow. It reduces the activity of an overactive bladder and enables you to wait longer before having to go to the bathroom.
Q: Can you take BEGROEASE S 50 TABLET every day?
A: Yes. Generally BEGROEASE S 50 TABLET is prescribed once a day. However, your doctor will evaluate your health condition and suggest you whether you can take BEGROEASE S 50 TABLET or not.
Q: Who should not take BEGROEASE S 50 TABLET?
A: BEGROEASE S 50 TABLET is not recommended for use in patients having severe liver or kidney diseases, severe stomach or bowel condition (ulcerative colitis), myasthenia gravis or glaucoma. Therefore, consult your doctor for advice.
Q: What is the use of BEGROEASE S 50 TABLET?
A: BEGROEASE S 50 TABLET is used to treat the signs of overactive bladder (such as sudden urge to pass urine, increased frequency of passing urine, unable to control urine and wetting yourself because you couldn’t go the bathroom).
Q: How BEGROEASE S 50 TABLET works in my body?
A: BEGROEASE S 50 TABLET is a muscle relaxant which relaxes the smooth muscles surrounding the bladder. This helps your bladder to hold more volume of urine and controls urine flow. As a result, it reduces the activity of an overactive bladder and enables you to wait longer before having to go to the bathroom.
Q: Can BEGROEASE S 50 TABLET cause dry mouth?
A: BEGROEASE S 50 TABLET may cause dry mouth in some individuals. To manage this, drink plenty of water to keep yourself hydrated. However, inform your doctor if this side effect troubles you.
Q: Can BEGROEASE S 50 TABLET be used during pregnancy?
A: BEGROEASE S 50 TABLET is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it.
Q: What is the best time to take BEGROEASE S 50 TABLET?
A: BEGROEASE S 50 TABLET can be taken at any time of the day. However, consult your doctor for advice.
Q: Can BEGROEASE S 50 TABLET cause dizziness?
A: Yes. BEGROEASE S 50 TABLET rarely causes dizziness in some individuals. If you experience dizziness, try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Consult your doctor if your dizziness worsens.
Q: How and when should I take BEGROEASE S 50 TABLET?
A: Take BEGROEASE S 50 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. [GBNKEYEORD] can be taken with or without food. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: Will BEGROEASE S 50 TABLET affect fertility?
A: No. BEGROEASE S 50 TABLET does not affect fertility . It only improves urinary symptoms associated with overactive bladder by relaxing the smooth muscles surrounding the bladder.
Q: How long will BEGROEASE S 50 TABLET take to cure my disease?
A: It may take up to 4 weeks for BEGROEASE S 50 TABLET to show the results. However, this period varies from person to person based on their disease condition. Consult your doctor if your symptoms are not relived even after taking BEGROEASE S 50 TABLET for a prolonged period.
Q: What to do if I forgot to take BEGROEASE S 50 TABLET?
A: If you forgot to take a dose of BEGROEASE S 50 TABLET take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose and take the next dose at regular times. Do not take a double dose to compensate a missed dose.
Q: Will taking a higher dose of BEGROEASE S 50 TABLET be more effective?
A: No. Do not take a higher dose of BEGROEASE S 50 TABLET than the prescribed one without consulting your doctor. Taking a higher dose of BEGROEASE S 50 TABLET may not be beneficial. Instead, it can cause serious side effects. If the prescribed dose is not effective for you, consult your doctor. Your doctor may prescribe a suitable higher dose or suggest an alternative therapy after evaluating your disease condition.
1. KD. Tripathi. Drugs Acting on ANS. Essentials of medical pharmacology. Seventh edition. 2013. Page – 118.
2. Paul Abrams, Con Kelleher, David Staskin, Tomasz Rechberger, Richard Kay, Reynaldo Martina, Donald Newgreen, Asha Paireddy, Rob van Maanen, Arwin Ridder. Combination treatment with mirabegron and solifenacin in patients with overactive bladder: efficacy and safety results from a randomised, double-blind, dose-ranging, phase 2 study (Symphony). NIH. National Library of Medicine. National Center for Biotechnology Information. Pubmed.gov. February 2014. [Accessed on 1st February 2023]. https://pubmed.ncbi.nlm.nih.gov/24612659/
3. Betmiga 25 mg prolonged-release tablets Betmiga 50 mg prolonged-release tablets mirabegron. Electronic Medicines Compendium. [Revised in December 2022]. [Accessed on 1st February 2023]. https://www.medicines.org.uk/emc/files/pil.7540.pdf
4. Zentiva, k.s. Electronic Medicines Compendium (EMC) [Revised in May 2020] [Accessed on 1st February 2023]. https://www.medicines.org.uk/emc/files/pil.10403.pdf
5. Cipla Ltd. Vesibeta – S Tablet. Ciplamed.com. [Revised in August 2021]. [Accessed on 1st February 2023]. https://ciplamed-library.com/content/vesibeta-s-tablets
6. Leeford Healthcare Pvt Ltd. Begroease-S 50. [Accessed on 1st February 2023]. https://www.leeford.in/product/1542/begroease-s-50
Written By Srilekha. R, B.Pharm
Last updated on 03 Feb 2023 | 04:39 PM(IST)