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INTRODUCTION BEGROEASE 50 TABLET contains Mirabegron which belongs to the group of medicines called Bladder muscle relaxants. BEGROEASE 50 TABLET is used in the treatment of managing the symptoms of overactive bladder (OAB) in adults such as an uncontrollable, sudden urge to urinate (urgency),...
BEGROEASE 50 TABLET contains Mirabegron which belongs to the group of medicines called Bladder muscle relaxants. BEGROEASE 50 TABLET is used in the treatment of managing the symptoms of overactive bladder (OAB) in adults such as an uncontrollable, sudden urge to urinate (urgency), feeling to pass urine many times during the day and night (increased urinary frequency) and the experience of unintentional loss of urine (urgency incontinence).
Your doctor will check the blood pressure while taking BEGROEASE 50 TABLET in patients with a history of high blood pressure.
BEGROEASE 50 TABLET is not recommended for use in patients having uncontrolled high blood pressure (hypertension) and patients who are allergic to mirabegron.
BEGROEASE 50 TABLET should be used with caution in patients with liver and kidney problems. BEGROEASE 50 TABLET is not recommended for use in pregnant women and need to be used with caution among breastfeeding women.
BEGROEASE 50 TABLET is generally not recommended for use in children and adolescents (under 18 years of age).
The most common side effects of taking BEGROEASE 50 TABLET are increased heart rate (tachycardia), infection of the body parts that carry urine (urinary tract infections), nausea, constipation, headache and diarrhoea. Talk to your doctor if symptoms get worsen or persists for a longer duration.
BEGROEASE 50 TABLET works by relaxing the muscles around your bladder during the storage phase of the urinary bladder fill-void cycle, which increases the bladder's capacity to hold more urine, thereby reducing the feelings of urgency and the need to urinate frequently.
Take BEGROEASE 50 TABLET as advised by your physician. Swallow BEGROEASE 50 TABLET with a glass of water and do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your age, body weight and disease condition.
Stop taking BEGROEASE 50 TABLET and contact your doctor immediately if you experience any of the following side effects:
Headache:
Try to rest and relax. Apply pain balm to the head to ease off the pain. Take hot water or ginger tea. If the symptom does not improve, contact your doctor.
Constipation:
Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. If the symptom does not improve, contact your doctor.
Diarrhoea:
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.
Dizziness:
Sit down or lie down slowly when you are feeling dizziness. Take rest for some time and drink plenty of water. Avoid coffee and other carbonated drinks. If the symptom does not improve, contact your doctor.
Nausea:
Take BEGROEASE 50 TABLET with, or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. If the symptom does not improve, contact your doctor.
BEGROEASE 50 TABLET is not recommended for use in pregnant women. Consult your doctor before taking BEGROEASE 50 TABLET.
BEGROEASE 50 TABLET should be used with caution in breastfeeding women, as it passes into your breast milk. Consult your doctor before taking BEGROEASE 50 TABLET. Your doctor would decide whether you should take the medication or breast-feed.
BEGROEASE 50 TABLET can be used with caution while driving or operating any machines, as it might affect your ability.
Avoid consumption of alcohol while taking BEGROEASE 50 TABLET. Consult your doctor before taking BEGROEASE 50 TABLET.
BEGROEASE 50 TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking to adjust the dose accordingly.
BEGROEASE 50 TABLET should be used with caution in patients with liver problems. Talk to your doctor before taking the medicine.
Do not take BEGROEASE 50 TABLET if you are allergic to Mirabegron or any other ingredients of this medicine.
BEGROEASE 50 TABLET is not recommended for patients with severe uncontrolled high blood pressure (hypertension). It should be used with caution in patients with heart rhythm disorders (QT prolongation). Consult your doctor before taking the medicine.
Use in pediatrics:
The safety and effectiveness of BEGROEASE 50 TABLET in pediatric patients have not been established. Consult your doctor before taking the medicine.
Use in geriatrics:
BEGROEASE 50 TABLET can be used in elderly patients with caution. However, consult your doctor before taking the medicine.
A. Drug-Drug Interactions:
Before taking BEGROEASE 50 TABLET, inform your doctor, if you are taking any of the following medicine:
Overdosage:
If you or anyone else accidentally took too much of BEGROEASE 50 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are increased pulse rate or an increased blood pressure.
| Drug | : | Mirabegron |
| Pharmacological Category | : | Beta 3-adrenoceptor agonists |
| Therapeutic Indication | : | Treats Overactive bladder |
| Dosage Forms | : | Tablet |
How long does BEGROEASE 50 TABLET take to work?
BEGROEASE 50 TABLET starts to work after about 3 to 4 hours to relax the muscle surrounding your bladder. However, it can take up to 4 to 8 weeks for you to notice any improvements in your symptoms. Consult your doctor for advice.
Can BEGROEASE 50 TABLET be used to control my urinary urgency?
Yes. BEGROEASE 50 TABLET works by relaxing the muscles around your bladder and holds more urine, and it is also used to treat other symptoms of the overactive bladder condition such as increased urinary frequency, and the inability to hold the urine.
Can BEGROEASE 50 TABLET increase your heart rate?
Yes. BEGROEASE 50 TABLET may cause heartbeat faster. If you experience any abnormally faster heart rate with shortness of breath, consult your doctor immediately. This might occur due to increased blood pressure.
What will happen if I stop taking BEGROEASE 50 TABLET?
Do not stop taking BEGROEASE 50 TABLET without consulting your doctor. If you suddenly stop taking this medicine, it will stop its action and your symptoms may come back or get worse.
Are there any lifestyle changes to follow along from BEGROEASE 50 TABLET?
There are lifestyle changes that may help your symptoms. Avoid drinks which can irritate your bladder, such as coffee, lose any excess weight, eating a healthy diet and undergoing bladder training and pelvic floor muscle training to ease off the symptoms.
1. KD. Tripathi. Antihypertensive drugs. Essentials of medical pharmacology. Eighth edition. 2019. Page – 139.
2. Omar Dawood; Ahmed El-Zawahry . Mirbegron. NIH National Library of Medicine, National center for biotechnology information. [Revised on July 2021][Accessed on 7th May 2022] https://www.ncbi.nlm.nih.gov/books/NBK538513/
3. Tan Denise Jia Yun, Weninger Julia, Goyal Anju; Mirabegron in Overactive Bladder and Its Role in Exit Strategy After Botulinum Toxin Treatment in Children ; Frontiers in Pediatrics. [February 2022 ] [Accessed on 7th May 2022] https://www.frontiersin.org/article/10.3389/fped.2021.801517
4. Makhani A, Thake M, Gibson W. Mirabegron in the Treatment of Overactive Bladder: Safety and Efficacy in the Very Elderly Patient. Clinical Interventions in Aging. [Revised April 2020] [Accessed on 7th May 2022] https://doi.org/10.2147/CIA.S174402
5. Astellas Pharma Europe B.V. Electronic Medicines Compendium (EMC). [Revised in January 2022] [7th May 2022] https://www.medicines.org.uk/emc/files/pil.2977.pdf
Written By Dr. Janet.C, Pharm.D
Last updated on 25 Nov 2022 | 05:49 PM(IST)