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INTRODUCTION ADVENT DROPS contains Amoxicillin and Clavulanic acid, which belong to the group of medicines called Penicillin and Beta-Lactamase Inhibitors. It is used in children for the treatment of various bacterial infections such as respiratory tract infections (such as pneumonia), urinary...
ADVENT DROPS contains Amoxicillin and Clavulanic acid, which belong to the group of medicines called Penicillin and Beta-Lactamase Inhibitors. It is used in children for the treatment of various bacterial infections such as respiratory tract infections (such as pneumonia), urinary tract infections (cystitis, urethritis, pyelonephritis), bone and joint infections, middle ear infections (otitis media), tonsillitis, sinusitis, skin, and soft tissue infections such as cellulitis, animal bites, dental infections (severe dental abscess), etc.
ADVENT DROPS is not recommended for use in patients with severe kidney impairment, history of liver problems or jaundice after taking penicillin antibiotics. ADVENT DROPS should be used with caution in patients suffering from glandular fever (viral infection causing sore throat, high fever, swelling of salivary glands, etc), liver disease, kidney disease, who are not passing urine daily.
ADVENT DROPS is not recommended for use in pregnant women unless clearly necessary. ADVENT DROPS should be used with caution in breastfeeding women as it may pass through breastmilk. ADVENT DROPS should be used with caution in neonates and infants less than 12 weeks of age. Consult your doctor before taking ADVENT DROPS. The most common side effects after taking ADVENT DROPS are vomiting, diarrhoea, nausea, thrush (fungal infections) etc. Consult your doctor immediately if your symptoms get worse or persist.
ADVENT DROPS help in treating bacterial infection where Amoxicillin works by inhibiting penicillin binding proteins (which are involved in the synthesis of bacterial cell wall) leading to activation of autolytic enzymes in the bacterial cell wall. Therefore, leading to lysis of the cell wall and death of bacterial cell and Clavulanic acid inhibits the activity of bacterial enzymes known as beta lactamases. As a result, it enhances the antibacterial activity of amoxicillin.
Take ADVENT DROPS as advised by your physician. Shake the medicine well before every use. Avoid contaminating the dropper. Your doctor will decide the exact dose and duration of treatment for you depending upon your age, body weight and disease condition.
Stop taking ADVENT DROPS and consult your doctor immediately in case you experience:
Nausea, vomiting:
Take the medicine, before meals. Stick to simple meals. Avoid eating oily or spicy food however, contact your doctor if your symptoms get worse or persist.
Itchy skin:
Avoid hot showers because hot water can irritate the skin and do not scratch the affected area. Apply moisturizing cream, Sunscreen and use protective clothing. Contact your doctor if your symptoms get worse or persist.
Stomach pain:
Try to rest and relax. Eat small meals but take frequently. Keep a heat pad on your stomach. Contact your doctor if your symptoms get worse or persist.
Diarrhoea:
Drink plenty of water or fruit juices to keep you hydrated. Don’t take any medicine on your own to treat diarrhoea. Contact your doctor if your symptoms get worse or persist.
Headache:
Rest and relax. Drink plenty of water and electrolytes. Apply a pain-relieving balm on the head if required. Contact your doctor if your symptoms get worse or persist.
ADVENT DROPS is not recommended for use in pregnant women unless clearly necessary. Consult your doctor before taking ADVENT DROPS.
ADVENT DROPS should be used with caution in breast feeding women as it may pass through breastmilk. Consult your doctor before taking ADVENT DROPS.
Do not drive or operate machinery after taking ADVENT DROPS.
ADVENT DROPS is not recommended for use in patients with severe kidney impairment. Consult your doctor taking ADVENT DROPS.
ADVENT DROPS is not recommend for use in patients who had history of liver problems or jaundice after taking penicillin antibiotics. Consult your doctor before taking ADVENT DROPS.
Do not take ADVENT DROPS if you are allergic to Amoxicillin, Clavulanic acid, or any other ingredients in this medicine.
Before taking ADVENT DROPS inform your doctor if you have:
Use in paediatrics:
ADVENT DROPS should be used with caution neonates and infants less than 12 weeks of age. Consult your doctor before giving ADVENT DROPS to your child.
A. Drug-Drug interactions:
Before taking ADVENT DROPS, inform your doctor if you are taking any of the following medicine:
Overdosage:
In case you or anybody else accidently take too much of ADVENT DROPS then consult your doctor immediately or visit the nearby hospital. Symptoms of overdose of ADVENT DROPS are nausea, diarrhoea, fits, disturbed fluid and electrolyte balance, crystalluria which may cause kidney failure.
| Drug | : |
Amoxicillin, Clavulanic acid |
| Pharmacological Category | : |
Penicillin and Beta-Lactamase Inhibitors |
| Therapeutic Indication | : |
Bacterial Infections |
| Dosage Forms | : | Tablet, Syrup, Oral Drops, Eye Drops, Ear Drops, Oral Suspension, Infusion, Dispersible Tablet, Dry Suspension, Dry Syrup, Granules |
What are uses of ADVENT DROPS?
ADVENT DROPS is used in children for treatment of various bacterial infections such as respiratory tract infections which includes pneumonia, urinary tract infections (cystitis, urethritis, pyelonephritis), bone and joint infections, middle ear infections (otitis media), tonsillitis, sinusitis, skin, and soft tissue infections ex. cellulitis, animal bites, dental infections (severe dental abscess), etc.
Can ADVENT DROPS cause tooth discolouration?
Yes, ADVENT DROPS can cause tooth discolouration in children which can be removed by regular brushing.
What are side effects of ADVENT DROPS?
The most common side effects after taking ADVENT DROPS are vomiting, diarrhoea, nausea, thrush (fungal infection), etc. Consult your doctor immediately in case any of side effects worsens.
How ADVENT DROPS works?
ADVENT DROPS help in treating bacterial infection where Amoxicillin works by inhibiting penicillin binding proteins (which are involved in the synthesis of bacterial cell wall) leading to activation of autolytic enzymes in the bacterial cell wall. Therefore, leading to lysis of the cell wall and death of bacterial cell and clavulanic acid inhibits the activity of bacterial enzymes known as beta lactamases and hence enhancing the antibacterial activity of amoxicillin.
Who should not take ADVENT DROPS?
ADVENT DROPS is not recommended for use in patients with severe kidney impairment, who had history of liver problems or jaundice after taking penicillin antibiotics. Consult your doctor before taking ADVENT DROPS.
1. KD Tripathi. Antimicrobial Drugs. Essentials of Medical Pharmacology, 7th edition. 2013. Page-723, 724.
2. Justin Evans, Maryam Hannoodee, Micah Wittler. Amoxicillin Clavulanate. National Centre for Biotechnology. NLM. National Institute of Health. Statpearls. December 2021. [Accessed on 21st October 2022] https://www.ncbi.nlm.nih.gov/books/NBK538164/#article-17475.s5
3. Misom Labs Ltd. Human Products and Regulatory Authority (HPRA). [Revised in June 2022] [Accessed on 21st October 2022] https://www.hpra.ie/img/uploaded/swedocuments/e910f270-5ef8-4a8f-8fac-bbefca807caa.pdf
4. Glaxo Wellcome Production. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 21st October 2022] https://www.medicines.org.uk/emc/files/pil.10038.pdf
5. GlaxoSmithKline Pharmaceuticals Limited. Amoxicillin + Clavulanic acid. [Revised in May 2022] [Accessed on 21st October 2022] https://india-pharma.gsk.com/media/6334/augmentin-duo-suspension.pdf
6. Medreich Limited. Amoxicillin + Clavulanic acid. [Revised in June 2015] [Accessed on 21st October 2022] http://www.paradigmpharma.com/CMS/IMAGES/pdfuploads/1503656556_Fleming%20(Co-Amoxiclav).pdf
7. Cipla Limited. Amoxicillin + Clavulanic acid. [Revised in December 2013] [Accessed on 21st October 2022] https://www.ciplamed.com/content/novamox-cv-injection-tablets-dt-syrup-drops#undesirable%20effects
8. Augpen Drops (Amoxicillin + Clavulanic acid). Zuventus Healthcare Limited. [Accessed on 21st October 2022] http://www.zuventus.co.in/doctor_wise_products_selected.aspx?Medi_Id=64
9. Bactoclav (Amoxicillin + Clavulanic acid). Micro Labs. [Accessed on 21st October 2022] http://www.microlabsltd.com/elibrary/node/1992
10. Noir Drops (Amoxicillin + Clavulanic acid). Arlak Biotech. [Accessed on 21st October 2022] https://www.arlakbiotech.com/products-offering/amoxycillin-potassium-clavulanate-oral-suspension-ip/
Written By Dr. Dhivakaran R, BDS
Last updated on 11 Nov 2022 | 05:48 PM(IST)