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INTRODUCTION AB PHYLLINE N TABLET is a combination of Acebrophylline and N-Acetylcysteine which belongs to the group of medicines called Bronchodilators and Mucolytics respectively. It is used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). It can also be used to t...
AB PHYLLINE N TABLET is a combination of Acebrophylline and N-Acetylcysteine which belongs to the group of medicines called Bronchodilators and Mucolytics respectively. It is used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). It can also be used to treat inflammation of the airways (such as bronchitis or cystic fibrosis) and reduce the onset of other complications caused due to mucus obstruction in the airways such as bronchospasm (paralysis of airways) and wheezing or shortness of breath.
Take AB PHYLLINE N TABLET preferably with meals or as advised by your physician. Before taking AB PHYLLINE N TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have fits, stomach ulcers, viral infections, hypertension or hyperthyroidism as a precaution.
AB PHYLLINE N TABLET is not recommended for use in pregnant and in breastfeeding women. The most common side effects of taking AB PHYLLINE N TABLET are epigastric pain, stomach discomfort, nausea, vomiting, dizziness, drowsiness, diarrhea and constipation. Consult your doctor if any of these side effects trouble you.
It is used to treat and prevent:
AB PHYLLINE N TABLET is a bronchodilator with anti-inflammatory and mucolytic properties. It blocks the release of certain chemicals (such as phosphodiesterase) in the respiratory tract that triggers airway inflammation, swelling and narrowing. As a result, it widens the airways, and reduces airway inflammation. It also loosens the mucus accumulated in the airways which allows the air to pass through more freely through the airways and makes breathing easier.
Take AB PHYLLINE N TABLET preferably with meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose and duration of therapy depending upon your age, body weight and disease condition.
Do not stop taking AB PHYLLINE N TABLET once your symptoms subside without consulting your doctor.
Stop taking this medicine and contact your doctor immediately if you experience any of the following side effects:
Nausea and Vomiting
Take AB PHYLLINE N TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your symptom worsens.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
AB PHYLLINE N TABLET is not recommended for use in pregnancy. Therefore, consult your doctor before taking it.
AB PHYLLINE N TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
AB PHYLLINE N TABLET usually does not affect your ability to drive or operate any machinery. However, do not drive or handle any heavy tools or machines if you feel dizzy or drowsy after taking AB PHYLLINE N TABLET.
AB PHYLLINE N TABLET is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems. Therefore, consult your doctor before taking it.
AB PHYLLINE N TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with hepatic dysfunction. Therefore, consult your doctor before taking it.
Do not take AB PHYLLINE N TABLET if you are allergic to N-Acetylcysteine, Acebrophylline or to any other methylxanthines (such as theophylline, doxophylline).
AB PHYLLINE N TABLET is not recommended for use in patients suffering from myocardial infarction or arrythmias. It should be used with caution in patients with heart failure or any other heart problems. Therefore, consult your doctor before taking it.
AB PHYLLINE N TABLET is not recommended for use if you:
Before taking AB PHYLLINE N TABLET, inform your doctor if you:
Use in paediatrics:
AB PHYLLINE N TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Use in geriatrics:
AB PHYLLINE N TABLET should be used with caution in the elderly patients. Therefore, consult your doctor before taking it.
A. Drug - Drug interactions:
Before taking AB PHYLLINE N TABLET, inform your doctor if you are taking any of the following medicines such as:
Overdosage:
If you or anyone else accidentally took more AB PHYLLINE N TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include nausea, vomiting, upper stomach pain, restlessness, fits, fast heart rate and hyperactivity.
| Drug | : | Acebrophylline, N-Acetylcysteine |
| Pharmacological Category | : | Methylxanthines, Mucolytics |
| Therapeutic Indication | : | Asthma, COPD, Bronchitis |
| Dosage Forms | : | Tablet, Capsule |
Q: How AB PHYLLINE N TABLET works?
A: AB PHYLLINE N TABLET widens the airways and reduces airway inflammation. It also loosens the mucus accumulated in the airways which allows the air to pass through more freely through the airways and makes breathing easier.
Q: What is the use of AB PHYLLINE N TABLET?
A: AB PHYLLINE N TABLET is used to treat asthma, COPD and bronchitis (inflammation of the airways). It can also reduce unpleasant symptoms associated with bronchospasm such as wheezing.
Q: Can I take AB PHYLLINE N TABLET daily?
A: AB PHYLLINE N TABLET is generally prescribed as one or two doses per day. However, your doctor will decide the number of doses per day depending upon your age, body weight and disease condition.
Q: How long does it take for AB PHYLLINE N TABLET to start working?
A: AB PHYLLINE N TABLET may start working within 2 hours of oral administration. However, it may take 2 weeks for AB PHYLLINE N TABLET to show improvements in your condition. Therefore, take AB PHYLLINE N TABLET regularly as informed by your doctor without fail to achieve better results.
Q: Is AB PHYLLINE N TABLET effective?
A: Yes. AB PHYLLINE N TABLET effectively controls the symptoms of asthma, COPD and bronchitis, by blocking the release of certain chemicals (phosphodiesterase) in the respiratory tract that triggers the allergic and inflammatory response. It also loosens the mucus and prevents the narrowing of the airway tract which makes breathing easier.
Q: What will happen if I consume a high dose of AB PHYLLINE N TABLET than prescribed by my doctor?
A: Do not consume a higher dose of AB PHYLLINE N TABLET than the one prescribed by your doctor, as it may lead to unwanted side effects. Your doctor will decide the correct dose for you, depending on your age and disease condition. If the prescribed dose, is not working for you, consult your doctor for advice.
Q: Is AB PHYLLINE N TABLET safe?
A: AB PHYLLINE N TABLET is considered safe at doses prescribed by the physician. However, it may cause few side effects such as epigastric pain, stomach discomfort, nausea, vomiting, dizziness, drowsiness, diarrhea and constipation in some individuals. Consult your doctor if any of these side effects trouble you.
Q: What should I do if I forgot to take a dose of AB PHYLLINE N TABLET?
A: If you forgot to take a dose of AB PHYLLINE N TABLET, take it as soon as possible. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose of AB PHYLLINE N TABLET to compensate the missed dose.
Q: Will taking a higher dose of AB PHYLLINE N TABLET be more effective?
A: No. Do not take a higher dose of AB PHYLLINE N TABLET than prescribed by your doctor, as it could lead to toxicity. Always consume the dose prescribed by your doctor. If you feel that the prescribed dose is not working for you, consult your doctor for advice.
Q: Can the use of AB PHYLLINE N TABLET make me feel dizzy?
A: AB PHYLLINE N TABLET may cause dizziness in some individuals. If you experience dizziness, try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Q: I’m pregnant. Can I take AB PHYLLINE N TABLET?
A: AB PHYLLINE N TABLET is generally not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
Q: Can AB PHYLLINE N TABLET be used in children?
A: AB PHYLLINE N TABLET is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Q: Can AB PHYLLINE N TABLET make you sleepy?
A: Yes. This medicine may make you feel sleepy or drowsy. Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.
Q: Can AB PHYLLINE N TABLET be used on an asthma attack?
A: No. AB PHYLLINE N TABLET is only used to prevent or manage the symptoms of asthma. If your asthma or breathing gets worse suddenly, contact your doctor immediately or go to the hospital straight away to avoid further exacerbation of the attack. Meanwhile use a fast-acting rescue inhaler along with AB PHYLLINE N TABLET.
Q: Can I stop using AB PHYLLINE N TABLET once my symptoms subside?
A: No. Continue to use AB PHYLLINE N TABLET as long as your doctor prescribes it to you. Do not stop using this medicine or reduce the dose suddenly without consulting your doctor as it may make it less effective.
1. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 219 & 224.
2. Sumit Roy Tapadar, Maumita Das, Arunabha Datta Chaudhuri, Santanu Basak, and Anil Baran Singha Mahapatra. The Effect of Acebrophylline vs Sustained Release Theophylline in Patients of COPD- A Comparative Study. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. September 2014. [Accessed on 11th January 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225926/
3. Pureun-Haneul Lee, Jisu Hong, and An-Soo Jang. N-acetylcysteine decreases airway inflammation and responsiveness in asthma by modulating claudin 18 expression. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. February 2020. [Accessed on 11th January 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487305/
4. Cipla Ltd. Mucophylin Capsules (Acebrophylline). [Revised in November 2013] [Accessed on 11th January 2023] https://www.ciplamed.com/print-product-pdf/24147
5. Ennogen Healthcare Limited. Acetylcysteine 600mg Capsules. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 1th January 2023] https://www.medicines.org.uk/emc/files/pil.11586.pdf
6. LaRenon Healthcare Pvt Ltd. Aphyren-N. Acetylcysteine 600mg+Acebrophylline 100mg Tablets. 2019. [Accessed on 11th January 2023] https://www.larenon.com/wp-content/uploads/2020/06/1.-Aphyren-N-LBL_ctc.pdf
7. Leeford Healthcare Pvt Ltd. Broncofil-N. [Accessed on 11th January 2023] https://www.leeford.in/product/566/broncofil-n
Written By Srilekha. R, B.Pharm
Last updated on 12 Jan 2023 | 03:59 PM(IST)