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INTRODUCTION FIBRICOR 0.1MG INJECTION contains Ibutilide, which belongs to the group of medicines called Antiarrhythmics. FIBRICOR 0.1MG INJECTION is used for converting the abnormal heart rhythm to a normal heart rhythm in conditions such as atrial flutter (due to rapid abnormal contraction o...
FIBRICOR 0.1MG INJECTION contains Ibutilide, which belongs to the group of medicines called Antiarrhythmics. FIBRICOR 0.1MG INJECTION is used for converting the abnormal heart rhythm to a normal heart rhythm in conditions such as atrial flutter (due to rapid abnormal contraction of the ventricles (lower heart chambers) of the heart) or atrial fibrillation (due to irregular electric impulses of the heart).
Atrial fibrillation and atrial flutter are conditions due to an uneven contraction of the parts in the heart, resulting in a fast and irregular heartbeat. Symptoms of the conditions may include palpitations, tiredness, shortness of breath, feeling faint or light-headed, and chest pain.
Your doctor may advise you to take relevant tests and evaluate your condition for hypokalaemia (low potassium levels) and hypomagnesemia (low magnesium levels) and stabilise their levels to reduce the potential for proarrhythmic events that may occur after receiving FIBRICOR 0.1MG INJECTION.
FIBRICOR 0.1MG INJECTION is not recommended for use in patients suffering from polymorphic ventricular tachycardia, such as torsade de pointes (the lower chambers of the heart work faster than the upper heart chambers), congenital long QT syndrome (a hereditary heart condition causing ventricular arrhythmia), sinus node disease, structural heart disease, and uncorrected electrolyte abnormalities.
FIBRICOR 0.1MG INJECTION should be used with caution in patients with QT prolongation, a family history of QT prolongation, recent myocardial infarction, bradycardia (slow heart rate), congestive heart failure or low ejection fraction, and heart block.
FIBRICOR 0.1MG INJECTION is not recommended for use and should be used with caution in pregnant women, only if recommended by your doctor, as it may cause harm to the unborn as its safety and risk are not known. [GBN] is not recommended for use in breastfeeding mothers or children less than 18 years of age, as its safety and risks have not been established. In elderly patients over the age of 65, FIBRICOR 0.1MG INJECTION should be used with caution.
The most common side effects of receiving FIBRICOR 0.1MG INJECTION may include headache, low blood pressure and bradycardia (slow heart rate). Contact your physician if any of the symptoms get worse.
FIBRICOR 0.1MG INJECTION works by regulating the heartbeat by blocking the abnormal electrical signals in the heart. Thus, treating abnormal heart rhythm effectively.
FIBRICOR 0.1MG INJECTION will be given to you only by a doctor or a nurse as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and severity of the disease.
Headache:
Take rest and relax. Drink plenty of water and electrolytes sufficient amount of fluids recommended by your doctor to keep yourself hydrated. Apply a pain-relieving balm to your forehead if needed. Contact your doctor if your headache did not improve.
Take rest and relax. Drink plenty of water and electrolytes a sufficient amount of fluids recommended by your doctor to keep yourself hydrated. Apply a pain-relieving balm to your forehead if needed. Contact your doctor if your headache did do not improve.
FIBRICOR 0.1MG INJECTION should be used with caution in pregnant women, only if recommended by your doctor as its safety and risk are not known. Consult your doctor before receiving it.
FIBRICOR 0.1MG INJECTION is not recommended for use in breastfeeding women as it is not known whether it could pass through breast milk. Consult your doctor before receiving it.
The safety and effectiveness of FIBRICOR 0.1MG INJECTION in patients with kidney disease have not been established. Consult your doctor before receiving it.
The safety and effectiveness of FIBRICOR 0.1MG INJECTION in patients with liver disease have not been established. Consult your doctor before receiving it.
Do not receive FIBRICOR 0.1MG INJECTION if you are allergic to ibutilide, tolbutilide fumarate, or any of the other ingredients of this medicine.
FIBRICOR 0.1MG INJECTION is not recommended for use in patients suffering from polymorphic ventricular tachycardia such as torsade’s de pointes pointes (the lower chambers of the heart work faster than the upper heart chambers), congenital long QT syndrome (hereditary heart condition causing ventricular arrhythmia), sinus node disease and structural heart disease. Consult your doctor before receiving it.
FIBRICOR 0.1MG INJECTION should be used with caution in patients with QT prolongation, a family history of QT prolongation, recent myocardial infarction, bradycardia (slow heart rate), Congestive heart failure or low ejection fraction and heart block. Consult your doctor before receiving it.
FIBRICOR 0.1MG INJECTION is not recommended for use if you have:
Use in paediatrics:
FIBRICOR 0.1MG INJECTION is not recommended for use in children below 18 years of age as its safety and risks in children are not yet established. Consult your doctor before receiving it.
Use in geriatrics:
FIBRICOR 0.1MG INJECTION should be used with caution in elderly patients 65 years of age. Consult your doctor before it.
A. Drug-Drug interactions:
Before receiving FIBRICOR 0.1MG INJECTION, inform your doctor if you are taking any of the following medicine:
Overdosage:
FIBRICOR 0.1MG INJECTION will be administered to you only by a doctor or a nurse in the hospital, so it is unlikely for you to receive an overdose. However, contact your physician immediately if you experience any unusual side effects. Symptoms of overdosage may include increased ventricular ectopy (extra abnormal heartbeats) and monomorphic ventricular tachycardia, AV block- 3rd degree and non-sustained polymorphic ventricular tachycardia.
| Drug | : | Ibutilide |
| Pharmacological Category | : | Antiarrhythmics |
| Therapeutic Indication | : | Rapid conversion of atrial flutter or atrial fibrillation into normal sinus rhythm |
| Dosage Forms | : | Injection |
What is FIBRICOR 0.1MG INJECTION used for?
FIBRICOR 0.1MG INJECTION is used for rapid conversion of atrial flutter or atrial fibrillation of rapid onset into normal sinus rhythm. Contact your doctor before receiving FIBRICOR 0.1MG INJECTION.
What are the side effects of FIBRICOR 0.1MG INJECTION?
The most common side effects of receiving FIBRICOR 0.1MG INJECTION are headache, low blood pressure and bradycardia (slow heart rate). Contact your doctor if any of the side effects get worsen.
How FIBRICOR 0.1MG INJECTION works?
FIBRICOR 0.1MG INJECTION works by regulating the heartbeat by blocking the abnormal electrical signals in the heart. Thus, treating abnormal heart rhythm effectively.
What is the difference between atrial fibrillation and atrial flutter?
Atrial fibrillation and Atrial flutter are conditions due to an uneven contraction of the parts of the heart resulting in a fast and irregular heartbeat. Atrial flutter occurs due to rapid abnormal contraction of the ventricles (lower heart chambers) of the heart. Atrial fibrillation occurs due to irregular electric impulses of the heart.
How quickly does FIBRICOR 0.1MG INJECTION work?
FIBRICOR 0.1MG INJECTION will start work in less than 90 minutes of administration. Consult your doctor for advice.
How do you administer FIBRICOR 0.1MG INJECTION?
FIBRICOR 0.1MG INJECTION will be given to you only by a doctor or a nurse as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and severity of the disease.
1. KD Tripathi. Antiarrhythmic Drugs. Essentials of medical pharmacology. 7th edition. 2013. Page- 535.
2. Linda Skidmore-Roth. Ibutilide. Mosby’s 2021 Nursing Drug Reference. 34th edition. 2021. Page- 657.
3. Michael W. Szymanski, Manouchkathe Cassagnol. National Centre for Biotechnology Information. NLM. National Institute of Health. Statpearls. April 2022. [Accessed on 3rd September 2022] https://www.ncbi.nlm.nih.gov/books/NBK526021/#article-23332.s6
4. Pharmacia & Upjohn Company LLC. Ibutilide. [Revised in January 2021] [Accessed on 3rd September 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=2428969a-7431-4e94-9503-ad5c680e2ea4
5. Pharmacia & Upjohn Company LLC. Ibutilide. [Revised in August 2016] [Accessed on 3rd September 2022] https://labeling.pfizer.com/showlabeling.aspx?id=673
6. Pfizer Canada Inc. Ibutilide. [Revised in October 2016] [Accessed on 3rd September 2022] https://pdf.hres.ca/dpd_pm/00036644.PDF
7. Ibutilide. Zuventus healthcare limited. [Accessed on 3rd September 2022] http://www.zuventus.co.in/doctor_wise_products_selected.aspx?Medi_Id=278
Written By Dr. Dhivakaran R, BDS
Last updated on 06 Dec 2022 | 05:06 PM(IST)