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INTRODUCTION DURON 150MG INJECTION contains Amiodarone which belongs to the group of medicines called Antiarrhythmics. It is used to treat uneven or fast heartbeats (like atrial flutter or atrial fibrillation), fast heartbeats which may happen suddenly and may be uneven only when other medicin...
DURON 150MG INJECTION contains Amiodarone which belongs to the group of medicines called Antiarrhythmics. It is used to treat uneven or fast heartbeats (like atrial flutter or atrial fibrillation), fast heartbeats which may happen suddenly and may be uneven only when other medicines either have not worked or cannot be used.
It also treats Wolff-Parkinson-White Syndrome (unusually fast heartbeats). It is normally only given in a hospital when a quick response is needed or when tablets cannot be given.
Your doctor might want you to keep out of direct sunlight while receiving DURON 150MG INJECTION and for a few months after you have finished receiving it. Avoid consumption of alcohol and grapefruit juice during treatment with DURON 150MG INJECTION.
DURON 150MG INJECTION is not recommended for use if you have severe breathing and blood circulation problems, slower than usual heartbeat (called ‘sinus bradycardia’) or an illness called sino-atrial heart block.
It is also not recommended if you have other problems with your heartbeat without a pacemaker fitted, are going to have a heart transplantation, have ever had thyroid problems or low blood pressure.
Before receiving DURON 150MG INJECTION, inform your doctor if you have heart failure or weak heart (cardiomyopathy), liver, kidney, thyroid, lung problems or asthma, require oxygen treatment, are to undergo a general anesthetic, or have eyesight problems (optic neuritis).
Also inform your doctor if you are about to have any surgery, blistering or peeling of the skin around the lips, eyes, mouth, nose and genitals, flu-like symptoms and fever (Stevens-Johnson syndrome), layers of the skin skin peeling off to leave large areas of raw exposed skin over the body (Toxic Epidermal Necrolysis).
DURON 150MG INJECTION is not recommended for pregnant or breastfeeding women. DURON 150MG INJECTION is contraindicated in premature babies or neonates and should be used with caution in infants and children up to 3 years old. Safety data has not been established in children and adolescents above 3 years of age.
DURON 150MG INJECTION should be used with caution in elderly patients above 60 years of age. The most common side effects of receiving DURON 150MG INJECTION are blurred eyesight, rashes, muscle weakness, difficulty sleeping, nightmares. Consult your doctor if any of the symptoms worsen.
It is usually used in hospitals when tablets cannot be given and a quick response is needed to treat:
DURON 150MG INJECTION works by blocking certain electrical signals and reducing the excitability of cardiac tissues which prevents the initiation and conduction of any new impulses in the heart that cause irregular heartbeats, thus making your heartbeat return to normal.
DURON 150MG INJECTION must be given by a doctor or nurse into the vein as an intravenous injection or infusion. Your doctor will decide the correct dose and duration of DURON 150MG INJECTION for you depending upon your age, body weight and disease condition.
Stop receiving DURON 150MG INJECTION and consult your doctor immediately if you experience any of the following side effects:
Dizziness, Fainting:
When you start receiving DURON 150MG INJECTION, you may feel faint or dizzy. This is caused by your blood pressure dropping. If this happens, resting or lying down for some time can help. Consult your doctor if symptoms don't improve.
Rash:
Applying a cold compress, cool showers or damp cloth, cold water can bring immediate relief to swelling and reduce itching. Consult your doctor if symptoms don't improve.
Muscle pain:
Hot compress helps to increase blood flow, which relaxes sore muscles and joints and reduces pain. Cold compress can reduce inflammation around the aching muscle or joint. Consult your doctor if symptoms don't improve.
DURON 150MG INJECTION is not recommended for use in pregnant women or women planning to have a baby, except in life-threatening circumstances. Consult your doctor before receiving it.
DURON 150MG INJECTION is not recommended for use in breastfeeding women. Consult your doctor before receiving it.
DURON 150MG INJECTION may affect your ability to drive or use machines. Consult your doctor before receiving it.
Limit the consumption of alcohol during treatment with DURON 150MG INJECTION. Consult your doctor before receiving it.
DURON 150MG INJECTION should be received with caution in patients with kidney problems. Consult your doctor before receiving DURON 150MG INJECTION.
DURON 150MG INJECTION should be received with caution in patients with liver problems. Consult your doctor before receiving it.
Do not receive DURON 150MG INJECTION if you are allergic to Amiodarone or any of the other ingredients of this medicine. Consult your doctor before receiving it.
DURON 150MG INJECTION is not recommended for use if you have severe breathing problems. DURON 150MG INJECTION should be received with caution in patients with asthma, or any other lung diseases. Consult your doctor before receiving it.
DURON 150MG INJECTION should not be given in patients with slower than usual heartbeat (called ‘sinus bradycardia’) or an illness called sino-atrial heart block, other problems with your heartbeat without a pacemaker fitted, are going to have a heart transplantation or have low blood pressure.
DURON 150MG INJECTION should be used cautiously in patients with heart failure or weak heart (cardiomyopathy) or low blood pressure. Consult your doctor before receiving DURON 150MG INJECTION.
DURON 150MG INJECTION is not recommended for use if you:
Before receiving DURON 150MG INJECTION, inform your doctor if you:
Use in pediatrics:
DURON 150MG INJECTION is contraindicated in premature babies or neonates and should be used with caution in infants and children up to 3 years old.
Safety data has not been established in children and adolescents above 3 years of age.
Use in geriatrics:
DURON 150MG INJECTION should be used with caution in elderly patients aged above 60 years. Consult your doctor before receiving DURON 150MG INJECTION.
A. Drug - Drug interactions:
Before receiving DURON 150MG INJECTION, inform your doctor if you are taking any of the following medicine:
B. Drug - Food interaction:
Avoid drinking grapefruit juice while receiving DURON 150MG INJECTION as it may increase the risk of side effects.
Overdosage:
DURON 150MG INJECTION will be given to you only by a doctor or nurse in a hospital and so it is unlikely to receive an overdose. However, if you experience any unusual symptoms like feeling dizzy, faint, sick, tired, confused or abnormally slow or fast heartbeats, contact your doctor immediately.
| Drug | : | Amiodarone |
| Pharmacological Category | : | Antiarrhythmic |
| Therapeutic Indication | : | Arrhythmias, Wolff-Parkinson-White Syndrome |
| Dosage Forms | : | Tablet, Injection |
What is DURON 150MG INJECTION used for?
DURON 150MG INJECTION is used to treat uneven or fast heartbeats (like atrial flutter or atrial fibrillation), fast heartbeats which may happen suddenly and may be uneven only when other medicines either have not worked or cannot be used. It also treats Wolff-Parkinson-White Syndrome (unusually fast heartbeats).
How does DURON 150MG INJECTION work?
DURON 150MG INJECTION works by blocking certain electrical signals and reducing the excitability of cardiac tissues which prevents the initiation and conduction of any new impulses in the heart that cause irregular heartbeats, thus making your heartbeat return to normal.
Can DURON 150MG INJECTION make my skin sensitive to the sun?
Yes. your skin will become much more sensitive to the sun after receiving DURON 150MG INJECTION and may burn, tingle or severely blister. Do not expose yourself to direct sunlight while receiving this medicine and for a few months after you have finished receiving it. Use high factor sun cream without fail. Always wear a hat and clothes which cover your whole body.
What should I avoid while receiving DURON 150MG INJECTION?
Avoid drinking grapefruit juice while receiving DURON 150MG INJECTION as it may increase the risk of side effects. Avoid consumption of alcohol during treatment with DURON 150MG INJECTION, as it may increase the chances of liver problems.
Will DURON 150MG INJECTION cause any reaction at the site of injection?
DURON 150MG INJECTION may cause swelling, pain, redness, infection and blue or grey marks on parts of your skin exposed to sunlight, especially the face. You can apply cold compress for relief. Consult your doctor before using any product for the reaction, other than DURON 150MG INJECTION.
1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Arrhythmias. Pharmacotherapy handbook. Ninth edition. Page- 48, 49.
2. KD. Tripathi. Antiarrhythmic Drugs. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 533.
3. HBM Pharma. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 20th April 2022] https://www.medicines.org.uk/emc/files/pil.3940.pdf, https://www.medicines.org.uk/emc/product/3940/smpc
4. Bioindustria Laboratorio Medicinali S.p.A. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 20th April 2022] https://www.medicines.org.uk/emc/files/pil.8739.pdf
Written By Dr. Shruthi M R, BDS
Last updated on 12 Jan 2023 | 10:04 AM(IST)