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INTRODUCTION CARNOSIN contains Adenosine which belongs to the group of medicines called Antiarrhythmics agents. It is used to treat arrhythmia (irregular heartbeat) in both adults and in children. It helps in bringing back the heartbeat to normal in case of a heart condition called paroxysmal...
CARNOSIN contains Adenosine which belongs to the group of medicines called Antiarrhythmics agents. It is used to treat arrhythmia (irregular heartbeat) in both adults and in children. It helps in bringing back the heartbeat to normal in case of a heart condition called paroxysmal supraventricular tachycardia or Wolff Parkinson-White Syndrome (fast heart rate caused due to abnormal electrical signals in the heart chambers). It can also be used to diagnose certain heart problems (such as the type of arrhythmia) during cardiac stress testing.
Before receiving CARNOSIN inform your doctor if you have any other heart problems other than arrhythmia (such as high or low blood pressure, prolonged QT interval, inflammation of heart lining, fluid build-up in heart, history of heart attack or heart transplantation surgery). You must also inform your doctor if you have low blood volume, epilepsy or any breathing difficulties such as asthma.
Consult your doctor before receiving CARNOSIN if you are pregnant or breastfeeding. During treatment with CARNOSIN your doctor will closely monitor your heart functions to avoid any unwanted side effects. Avoid consuming tea, coffee or cola at least for 12 hours before receiving CARNOSIN.
The common side effects of receiving CARNOSIN are nausea, dizziness, numbness, flushing or warmth and difficulty in breathing. Consult your doctor if any of these side effects trouble you.
CARNOSIN is an anti-arrhythmic medicine. It regulates the heart rate by blocking the generation of abnormal electrical signals in the heart. This normalizes your heart rate which therefore provides relief from the unpleasant symptoms of arrhythmia.
When used during stress testing, CARNOSIN improves blood supply to the heart by dilating the coronary arteries. This simulates an effect of a physical exercise (such as walking on a treadmill) in patients, which would help in diagnosing the problems with their heart functions.
CARNOSIN will be given to you only by a doctor or a nurse into the vein as an intravenous injection. Your doctor will decide the correct dose, duration of therapy and frequency of administration depending upon your age, body weight and health condition.
Consult your doctor if you experience any of the following side effects after receiving CARNOSIN:
Headache:
Try to take rest. Apply a pain-relieving balm on your forehead. If the symptom does not improve, consult with your doctor.
Dizziness:
Lie down until dizziness passes away and then move slowly and carefully. Take plenty amount of rest and drink plenty of fluids. If your symptom does not improve consult your doctor.
CARNOSIN is not recommended for use in pregnant women unless considered necessary by your doctor. Therefore, consult your doctor for advice before receiving it.
CARNOSIN is not recommended for use in breastfeeding mothers. Therefore, consult your doctor for advice before receiving it.
Do not drive or operate any heavy tools or machines if your ability is affected by CARNOSIN.
Avoid consumption of alcohol while receiving CARNOSIN.
Do not receive CARNOSIN if you are allergic to Adenosine.
CARNOSIN is not recommended for use in patients with severe lung disease (such as asthma or other breathing problems). Therefore, consult your doctor for advice before receiving it.
CARNOSIN should not be used in patients who have problems in their heart rhythm without a pacemaker. It is also not recommended for use in patients with other heart problems (such as severe low blood pressure or heart failure). It should be used with caution in patients having narrowed arteries or valves in heart, prolong QT interval, presence of shunt in the heart, or previous history of heart attack or heart transplantation. Therefore, consult your doctor for advice before receiving it.
Before receiving CARNOSIN, inform your physician if you:
Use in pediatrics:
CARNOSIN should be used in children and adolescents (aged below 18 years) only if prescribed by the physician. Therefore, consult your doctor for advice before administration.
Use in geriatrics:
CARNOSIN should be used with caution in elderly patients. Therefore, consult your doctor for advice before receiving it.
A. Drug - Drug interactions:
Before receiving CARNOSIN, inform your doctor if you are taking any of the following medicines:
Overdosage:
CARNOSIN will be given to you only by a doctor or a trained health care practitioner in a hospital. However, if you experience any unpleasant symptoms such as very low blood pressure or slow heartbeat contact your doctor immediately.
| Drug | : | Adenosine |
| Pharmacological Category | : | Group V Antiarrhythmic Agents |
| Therapeutic Indication | : | Arrhythmia |
| Dosage Forms | : | Injection |
What is the use of CARNOSIN?
CARNOSIN is used to treat arrhythmia (irregular heartbeat) in both adults and in children. It can also be used to diagnose certain heart problems (such as the type of arrhythmia) during cardiac stress testing.
How CARNOSIN works for stress testing?
When used during stress testing, CARNOSIN improves blood supply to the heart by dilating the coronary arteries. This simulates an effect of a physical exercise (such as walking on a treadmill) in patients, which would help in diagnosing the problems with their heart functions.
Is CARNOSIN safe?
CARNOSIN is safe when used under proper medical supervision and at the prescribed doses.
Can CARNOSIN cause low blood pressure?
Yes. The use of CARNOSIN may cause low blood pressure (hypotension) in some individuals. Therefore, inform your doctor before receiving CARNOSIN if you already have a very low blood pressure.
What foods should be avoided while receiving CARNOSIN?
It is advised not to consume tea, coffee chocolate, cola and other xanthine containing foods and drinks for at least 12 hours before receiving CARNOSIN. However, consult your doctor for advice.
What CARNOSIN does to my heart?
CARNOSIN regulates the heart rate by blocking the generation of abnormal electrical signals in the heart. This normalizes your heart rate which therefore provides relief from the unpleasant symptoms of arrhythmia. It also mimics the effect of a physical exercise by increasing blood supply to the heart which helps in diagnostic heart problems.
Is CARNOSIN safe for use while taking a blood thinner?
Before receiving CARNOSIN inform your doctor if you are taking medications used to thin the blood such as dipyridamole. Your doctor will evaluate the risks and benefits and suggest you a proper solution.
How long should I take CARNOSIN?
CARNOSIN will be given to you by a doctor or trained health care professional after outweighing the risks and benefits. Your doctor will decide the dose and frequency of CARNOSIN for use depending upon your age, body weight and severity of your disease condition. Consult your doctor for advice.
Is CARNOSIN safe for use in patient with asthma?
CARNOSIN is not recommended for use in patients with severe lung diseases or severe breathing illnesses such as asthma. Consult your doctor before receiving CARNOSIN.
Can CARNOSIN change my taste sensation?
Yes. CARNOSIN may cause changes in the taste sensation (such as metallic taste in the mouth). Consult your doctor if it bothers you.
1. KD. Tripathi. Antiarrhythmic Drugs. Essentials of medical pharmacology. 8th Edition. 2019. Page – 581.
2. John P. Dimarco, T. Duncan Sellers, Robert M. Berne, G. Alexander West, And Luiz Belardinelli. Adenosine: electrophysiologic effects and therapeutic use for terminating paroxysmal supraventricular tachycardia. Therapy and Prevention Arrhythmia. AHA journals. June 2020. [Accessed on 6th September 2022]. https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.68.6.1254
3. Wockhardt UK Ltd. Electronic Medicines Compendium (EMC). [Revised in April 2019]. Accessed on 6th September 2022]. https://www.medicines.org.uk/emc/files/pil.4766.pdf
4. Astellas Pharma US, Inc. U.S. Food and Drug Administration (FDA). [Accessed on 4th June 2021]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019937s026lbl.pdf