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INTRODUCTION CAFIRATE ORAL 20MG SOLUTION contains Caffeine which belongs to the group of medicines called CNS stimulants. It is used to treat primary apnea (episodes of interrupted breathing) in premature babies. Primary apnea in premature babies happens due to immature development of baby’s b...
CAFIRATE ORAL 20MG SOLUTION contains Caffeine which belongs to the group of medicines called CNS stimulants. It is used to treat primary apnea (episodes of interrupted breathing) in premature babies. Primary apnea in premature babies happens due to immature development of baby’s breathing centers.
CAFIRATE ORAL 20MG SOLUTION has been shown to reduce the number of episodes of interrupted breathing in premature newborns babies. It can also be used to treat and prevent bronchopulmonary dysplasia (airway damage) among premature babies.
Before CAFIRATE ORAL 20MG SOLUTION is administered, inform your doctor if you child has any liver, kidney or heart problems. You must also inform your doctor if your child suffers from seizure disorders, slow weight gain or frequent regurgitation (spitting up of milk or food) as a precaution.
If you are the mother of the premature infant who receives the treatment, you must not drink coffee or take foods which has high caffeine content. This is because the caffeine taken by the breastfeeding mother may pass through the breast milk to the nursing premature infant who is already receiving caffeine therapy and may lead to an overdosage. The most common side effect of CAFIRATE ORAL 20MG SOLUTION is fast or irregular heart rate. Consult your doctor if it worsens.
CAFIRATE ORAL 20MG SOLUTION is a CNS stimulant. It works by stimulating a part of the brain that controls breathing. As a result, the brain transfers a lot of breathing signals to the lungs which makes the lungs breathe more deeper and faster. It also increases the number of breathing cycles, prevents the airway damage and reduces the need for mechanical ventilation.
CAFIRATE ORAL 20MG SOLUTION will be administered orally (via gastric feeding tube) to your child only by a doctor or a nurse.
Your doctor will decide the correct dose and duration of therapy for your child based on their gestational age, body weight and health condition.
Contact your doctor immediately if you notice any of the following side effects in your child after CAFIRATE ORAL 20MG SOLUTION is administered:
If you are the mother of the premature infant who receives the treatment, you must not drink coffee or take foods which has high caffeine content. This is because the caffeine taken by the breastfeeding mother may pass through the breast milk to the nursing premature infant who is already receiving caffeine therapy and may lead to an overdosage.
CAFIRATE ORAL 20MG SOLUTION should be used with caution in babies with kidney problems. Therefore, inform your doctor as a precaution.
CAFIRATE ORAL 20MG SOLUTION should be used with caution in babies with liver problems. Therefore, inform your doctor as a precaution.
If your child is allergic to caffeine, kindly inform your doctor before CAFIRATE ORAL 20MG SOLUTION is administered to the child.
CAFIRATE ORAL 20MG SOLUTION should be used with caution in babies with heart problems (such as irregular heart rate). Therefore, inform your doctor as a precaution.
CAFIRATE ORAL 20MG SOLUTION can be used in premature infants born between 28-33 gestation weeks (7-8 months of pregnancy) under careful medical supervision.
Before CAFIRATE ORAL 20MG SOLUTION is administered to the baby, kindly inform the doctor if your baby suffers from any of the following conditions:
A. Drug-Drug interactions:
Before CAFIRATE ORAL 20MG SOLUTION is administered to the child, kindly inform the doctor if your child is given any of the following medicines as a precaution:
Overdosage:
CAFIRATE ORAL 20MG SOLUTION will be administered only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor if you notice fits or any other side effects in your child.
| Drug | : | Caffeine |
| Pharmacological Category | : | Methylxanthines |
| Therapeutic Indication | : | Apnea of prematurity in infants |
| Dosage Forms | : | Tablet, Injection, Oral solution, Suspension |
Q: What is the use of CAFIRATE ORAL 20MG SOLUTION?
A: CAFIRATE ORAL 20MG SOLUTION is used to treat primary apnea (episodes of interrupted breathing) in premature babies. It can also be used to treat and prevent bronchopulmonary dysplasia (airway damage) among premature babies.
Q: How CAFIRATE ORAL 20MG SOLUTION helps in breathing problems?
A: CAFIRATE ORAL 20MG SOLUTION is a CNS stimulant. It works by stimulating a part of the brain that controls breathing. As a result, the brain transfers a lot of breathing signals to the lungs which makes the lungs breathe more deeper and faster. It also increases the number of breathing cycles, prevents the airway damage and reduces the need for mechanical ventilation.
Q: Is CAFIRATE ORAL 20MG SOLUTION safe for use in children?
A: CAFIRATE ORAL 20MG SOLUTION can be used in premature infants born between 28-33 gestation weeks (7-8 months of pregnancy) under careful medical supervision.
Q: Why newborn babies suffer from apnea?
A: Primary apnea in premature babies happens due to immature development of baby’s breathing centers.
Q: What are the side effects of CAFIRATE ORAL 20MG SOLUTION?
A: The most common side effect of CAFIRATE ORAL 20MG SOLUTION is fast or irregular heart rate. Consult your doctor if it worsens.
Q: Is CAFIRATE ORAL 20MG SOLUTION effective?
A: CAFIRATE ORAL 20MG SOLUTION effectively improves breathing among infants suffering from apnea of prematurity. It works by stimulating a part of the brain that controls breathing. It also increases the number of breathing cycles, prevents the airway damage and reduces the need for mechanical ventilation.
1. KD. Tripathi. Drugs for Cough and Bronchial asthma. CNS Stimulants and Cognition Enhancers. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 224, 227& 488.
2. Justin Evans; John R. Richards; Amanda S. Battisti. Caffeine. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2022. [Accessed on 25th March 2023] https://www.ncbi.nlm.nih.gov/books/NBK519490/
3. Macarthys Laboratories Limited. Caffeine Citrate Oral solution. Electronic Medicines Compendium [Revised in July 2018] [Accessed on 25th March 2023] https://www.medicines.org.uk/emc/files/pil.5145.pdf
4. American Regent, Inc. Caffeine Citrate Injection, Solution. Dailymed.com. [Revised in September 2020]. [Accessed on 25th March 2023] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d17e3be5-514f-454a-8347-d804cd5ec37f
5. Central Drugs Standard Control Organization. Caffeine Citrate Oral Solution. July 2009. [Accessed on 25th March 2023] https://cdscoonline.gov.in/CDSCO/Drugs
Written By Srilekha. R, B.Pharm
Last updated on 27 Mar 2023 | 05:47 PM(IST)