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INTRODUCTION ANXIPAN CAPSULE is a combination of Amitriptyline, Pantoprazole which belongs to the group of medicines called Antidepressants and Proton pump inhibitors respectively. It is used in the treatment of Gastroesophageal reflux disease associated with anxiety. Gast...
ANXIPAN CAPSULE is a combination of Amitriptyline, Pantoprazole which belongs to the group of medicines called Antidepressants and Proton pump inhibitors respectively. It is used in the treatment of Gastroesophageal reflux disease associated with anxiety.
Gastroesophageal reflux disease is a condition characterized by the backflow of stomach contents like acid into the esophagus (food pipe), causing several symptoms, such as heartburn, chest pain and discomfort in which some patients may develop psychotic factors like anxiety and depression.
ANXIPAN CAPSULE is not suitable for use in patients with severe liver disease and heart problems such as heart attack. Consult your doctor for advice.
ANXIPAN CAPSULE is not recommended for use in pregnant or breast-feeding woman. Consult your doctor for advice.
ANXIPAN CAPSULE is generally not recommended for use in children and adolescents below 12 years of age and it should be used with caution in patients above 65 years of age.
The common side effects of taking ANXIPAN CAPSULE are slurred speech, excessive sweating, drowsiness, dry mouth and constipation Consult your doctor if the symptom does not improve.
ANXIPAN CAPSULE is a combination of Amitriptyline and Pantoprazole which treat gastroesophageal reflux disease (GERD) associated with anxiety. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression. Pantoprazole is a proton pump inhibitor which reduces the amount of acid in the stomach and relieves acid-related indigestion and heartburn.
Take ANXIPAN CAPSULE as advised by your physician. Swallow the medicine with a glass of water and do not crush or chew the medicine. Your doctor will decide the correct dose depending upon your age, body weight and disease condition.
Stop taking ANXIPAN CAPSULE and contact your doctor immediately if you experience any of the following side effects:
Constipation:
Eat plenty of fibre-rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly.
Drowsiness:
When you feel drowsy, lie, or sit down immediately. If you're feeling severe episodes of vertigo, lie in a dark and quiet place with your eyes closed. Vehicle driving should be avoided if you experience frequent drowsiness without warning. Talk to your doctor if the symptom is not improving.
Dry mouth:
Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your physician for advice.
Stomach pain:
Try to rest and relax. Try to have smaller and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.
Flatulence:
Eat smaller and more frequent meals. Eat and drink slowly, and exercise regularly. If the symptom does not improve. Contact your doctor for advice.
ANXIPAN CAPSULE is not recommended for use in pregnant woman or if you think you might become pregnant. Consult your doctor before taking ANXIPAN CAPSULE.
ANXIPAN CAPSULE is not recommended for use in breastfeeding women as it may pass through breastmilk to the baby. Consult your doctor for advice.
Do not drive or operate any machines if you feel dizzy or have vision disturbance after taking this medicine. Consult your doctor before taking ANXIPAN CAPSULE.
Avoid consumption of alcohol while taking this medicine as it may cause sleepiness.
ANXIPAN CAPSULE is not recommended for use in patients with severe liver disease. Consult your doctor before taking ANXIPAN CAPSULE.
Do not take ANXIPAN CAPSULE if you are allergic to Amitriptyline and Pantoprazole or any other ingredients of this medicine.
ANXIPAN CAPSULE is not recommended for use in patients who had heart attack or any other heart problems like disturbance in heart rhythm. Consult your doctor before taking ANXIPAN CAPSULE.
Before taking ANXIPAN CAPSULE, inform your doctor if you:
Use in pediatrics:
ANXIPAN CAPSULE is not recommended for use in children and adolescents below 12 years of age. Consult your doctor before taking ANXIPAN CAPSULE.
Use in geriatrics:
ANXIPAN CAPSULE should be used with caution in elderly patients. Before taking ANXIPAN CAPSULE, consult your doctor.
A. Drug-Drug interactions:
Before taking ANXIPAN CAPSULE inform your doctor if you are taking any of the following medicine:
Overdosage:
If you or anyone else accidentally took too much of ANXIPAN CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include dilated pupils, fast or irregular heartbeats, difficulty in urination, dry mouth and tongue, fits, fever, agitation, confusion, hallucinations, uncontrolled movements, low blood pressure, weak pulse, pallor, difficulty breathing, and drowsiness.
| Drug | : | Amitriptyline, Pantoprazole |
| Pharmacological Category | : | Tricyclic Antidepressants, Proton pump inhibitors |
| Therapeutic Indication | : | Gastroesophageal reflux disease associated with anxiety diorders |
| Dosage Forms | : | Capsule |
Q: What is ANXIPAN CAPSULE and why it is given?
A: ANXIPAN CAPSULE contains Amitriptyline and Pantoprazole which is used for treatment of Gastroesophageal reflux disease (backflow of stomach contents into food pipe) associated with anxiety.
Q: Can pregnant and breastfeeding woman take ANXIPAN CAPSULE?
A: ANXIPAN CAPSULE is not recommended for use in pregnant woman and breastfeeding women as it may pass through breastmilk to the baby. Consult your doctor for advice before taking ANXIPAN CAPSULE.
Q: Does ANXIPAN CAPSULE cause dry mouth?
A: One of the common side effects of ANXIPAN CAPSULE is dry or sore mouth and throat. It can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying.
Q: Can I take ANXIPAN CAPSULE if I have heart disease?
A: ANXIPAN CAPSULE is not recommended for use in patients who had heart attack or any other heart problems like disturbance in heart rhythm. Discuss with your doctor before taking it.
1. KD. Tripathi. Antidepressants and Anti-Anxiety Drugs, Drugs for Peptic Ulcer and Gastroesophageal Reflux Disease. Essentials of medical pharmacology. Eighth edition. 2019. Page –485-486, 701.
2. Arif A. Faruqui. Gastroesophageal Reflux Disease Associated with Anxiety: Efficacy and Safety of Fixed Dose Combination of Amitriptyline and Pantoprazole. National Library of Medicine, National center for biotechnology information. PubMed Central. Revised in October 2017. [Accessed 14th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667696/
3. Efficacy And Safety of Fixed Dose Combination of Pantoprazole And Low Dose Amitriptyline In Indian Population Suffering From GERD With Co- Existing Anxiety. Arif A. Faruqui. Symbiosis. Revised in March 2018. [Accessed 14th June 2022] https://symbiosisonlinepublishing.com/gastroenterology-pancreatology-liverdisorders/gastroenterology-pancreatology-liverdisorders122.php
4. APL Swift Services (Malta) Limited. Electronic Medicines Compendium (EMC). [Revised in December 2020] [Accessed 14th June 2022] https://www.medicines.org.uk/emc/files/pil.7090.pdf
5. Accord, Barnstaple, EX32 8NS, UK. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed 14th June 2022] https://www.medicines.org.uk/emc/files/pil.5698.pdf
Written By Dr. Janet.C, Pharm.D
Last updated on 03 Jan 2023 | 01:58 PM(IST)