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INTRODUCTION ANGIDIL SR TABLET contains Ranolazine which belongs to the group of medicines called Antianginals. It is used to treat chronic angina. Angina pectoris can be defined as a sudden, sharp and severe chest pain that originates from the apex of the heart and radiat...
ANGIDIL SR TABLET contains Ranolazine which belongs to the group of medicines called Antianginals. It is used to treat chronic angina.
Angina pectoris can be defined as a sudden, sharp and severe chest pain that originates from the apex of the heart and radiates to the left shoulder. It can be characterized by the presence of severe and crushing pain along with a feeling of pressure and suffocation, especially behind the breastbone.
ANGIDIL SR TABLET is not recommended for use in patients with severe kidney disease, moderate to severe liver disease. Contact your doctor before taking.
ANGIDIL SR TABLET should be used with caution in patients with mild to moderate kidney disease, mild liver disease and moderate to severe heart failure, abnormal ECG changes like like QT prolongation or long QT syndrome. Contact your doctor before taking.
ANGIDIL SR TABLET is generally not recommended for use in pregnant women unless considered clearly necessary. Contact your doctor before taking. ANGIDIL SR TABLET is not recommended for use in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before taking it.
ANGIDIL SR TABLET is not recommended for use in children and adolescents under 18 years of age. Contact your doctor before taking.
ANGIDIL SR TABLET should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking.
Avoid drinking grapefruit juice as it may lead to unwanted effects. The most common side effects of taking ANGIDIL SR TABLET are nausea, vomiting, constipation, dizziness headache and weakness. Contact your doctor if any of the above side effects worsen.
ANGIDIL SR TABLET works by inhibiting the entry of sodium and potassium into the heart cells, thereby preventing the calcium influx causing vasodilation and reduces ventricular tension, myocardial oxygen demand. Thus, relieving angina symptoms.
Take ANGIDIL SR TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Stop taking ANGIDIL SR TABLET and contact your doctor immediately if you experience any of the following side effects:
Headache:
Rest and relax. Drink plenty of fluids such as water and electrolytes. Apply a pain-relieving balm on the head if necessary. Do not consume alcohol. Contact your doctor if the symptom did not improve.
Nausea and Vomiting:
Take the medicine, with or just after a meal. Stick to simple meals. Avoid eating oily or spicy food.
Constipation:
Eat plenty of fibre rich foods such as fresh fruits, vegetables and cereals. Drink plenty of water and exercise more regularly.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Contact your doctor if the symptom did not improve.
ANGIDIL SR TABLET is not recommended for use in pregnant women unless considered clearly necessary. Contact your doctor before taking ANGIDIL SR TABLET.
ANGIDIL SR TABLET is not recommended for use in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before taking ANGIDIL SR TABLET.
Do not drive or operate any machines if you feel dizziness, lightheadedness, faintness, blurred vision, confusion, hallucination, double vision and coordination problems after taking ANGIDIL SR TABLET.
ANGIDIL SR TABLET is not recommended for use in patients with severe kidney disease and should be used with caution in mild to moderate kidney disease. Contact your doctor before taking ANGIDIL SR TABLET.
ANGIDIL SR TABLET is not recommended for use in patients with moderate to severe liver disease and should be used with caution in mild liver disease. Contact your doctor before taking ANGIDIL SR TABLET.
Do not take ANGIDIL SR TABLET if you are allergic to Ranolazine or to lactose or other sugars or to any other ingredients of this medicine.
ANGIDIL SR TABLET should be used with caution in patients with moderate to severe heart failure, abnormal ECG changes like QT prolongation or long QT syndrome. Contact your doctor before taking ANGIDIL SR TABLET.
ANGIDIL SR TABLET is not recommended for use if you have:
Use in pediatrics:
ANGIDIL SR TABLET is not recommended for use in children and adolescents under 18 years of age. Contact your doctor before taking ANGIDIL SR TABLET.
Use in geriatrics:
ANGIDIL SR TABLET should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking ANGIDIL SR TABLET.
A. Drug - Drug interactions:
Before taking ANGIDIL SR TABLET, inform your doctor if you are taking any of the following medicine:
B. Drug - Food interaction:
Avoid drinking grapefruit juice with this medicine as it may lead to unwanted effects. Consult your doctor for advice.
Overdosage:
If you or anyone else accidentally takes too much of ANGIDIL SR TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are dizziness, nausea and vomiting.
| Drug | : | Ranolzine |
| Pharmacological Category | : | Antianginals |
| Therapeutic Indication | : | Chronic angina |
| Dosage Forms | : | Tablet |
Who should avoid taking ANGIDIL SR TABLET?
ANGIDIL SR TABLET is not recommended for use in patients with allergic history to Ranolazine or lactose or rare hereditary problems like galactose intolerance, the Lapp lactase deficiency and glucose-galactose malabsorption, severe kidney disease, moderate to severe liver disease. Contact your doctor before taking ANGIDIL SR TABLET.
How ANGIDIL SR TABLET works?
ANGIDIL SR TABLET works by inhibiting the entry of sodium and potassium into the heart cells, thereby preventing the calcium influx causing vasodilation and reduces ventricular tension, myocardial oxygen demand. Thus, relieving angina symptoms.
What are the side effects of taking ANGIDIL SR TABLET?
The most common side effects of taking ANGIDIL SR TABLET are nausea, vomiting, constipation, dizziness headache and feeling weak. Contact your doctor if any of the symptoms worsen.
Does ANGIDIL SR TABLET cause hyponatremia?
Yes. ANGIDIL SR TABLET may cause hyponatremia. Contact your doctor if you experience any unusual symptoms like tiredness, confusion, muscle twitching, cramps.
Can I take grapefruit juice while taking ANGIDIL SR TABLET?
No. Avoid drinking grapefruit juice with this medicine as it may lead to unwanted effects. Contact your doctor before taking.
1. KD. Tripathi. Cardiovascular drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page -554.
2. Robert J. Kizior, Keith J. Hodgson. Ranolazine. Saunders Nursing Drug Handbook 2021. 28th edition. 2021. page-1000.
3. Menarini. Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC). [Revised on December 2021] [Accessed on 4th June 2022] https://www.medicines.org.uk/emc/files/pil.6442.pdf
4. Gilead Sciences, Inc. U.S. Food & Drug Administration. [Revised on January 2016] [Accessed on 4th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021526s029lbl.pdf
5. Gilead Sciences, Inc. Ranolazine. [Revised on April 2010] [Accessed on 4th June 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8d442b8c-97a8-40a9-8603-f9cd0542cedc
6. Ranolazine. Torrent Pharmaceuticals ltd. [Revised on July 2019] [Accessed on 4th June 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1344.pdf
Written By Dr. Janet.C, Pharm.D
Last updated on 22 Nov 2022 | 11:30 PM(IST)