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INTRODUCTION ABOUT AMDEPIN AT TABLET AMDEPIN AT TABLET is a combination of Amlodipine and Atenolol which belongs to the group of medicine called Antihypertensive agents. It is used to treat hypertension (also known as high blood pressure) and angina pectoris (chest pain caused due to lack of o...
AMDEPIN AT TABLET is a combination of Amlodipine and Atenolol which belongs to the group of medicine called Antihypertensive agents. It is used to treat hypertension (also known as high blood pressure) and angina pectoris (chest pain caused due to lack of oxygen supply to the heart). It can also be used to reduce the risk of heart attack (myocardial infarction) among heart patients.
Take AMDEPIN AT TABLET as advised by your physician. Avoid drinking grapefruit juice while taking AMDEPIN AT TABLET, as it could further decrease your blood pressure and may make you feel dizzier, drowsier or faint.
Before taking AMDEPIN AT TABLET, inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have asthma, diabetes, overactive thyroid gland or low blood volume as a precaution.
AMDEPIN AT TABLET is not recommended for use in patients with other severe heart problems apart from hypertension and angina (such as heart failure). It is also not suitable for use in patients with severe hypotension (low blood pressure).
Consult your doctor before taking AMDEPIN AT TABLET if you are pregnant or breastfeeding. The most common side effects of taking AMDEPIN AT TABLET are swelling of ankles or other body parts, headache, dizziness, sleepiness, tiredness, racing heartbeat, indigestion, constipation, muscle cramps, cold hands and feet and slow heartbeat. Contact your doctor if any of these side effects trouble you.
AMDEPIN AT TABLET contains two medicines namely amlodipine and atenolol. Atenolol blocks the effects of certain hormones (adrenaline) in the body that naturally increases heart rate. This slows down the heartbeat and makes the heart to pump blood with a lesser force.
Amlodipine is a vasodilator. It relaxes the blood vessels supplying the heart which improves blood flow and oxygen supply to the heart muscles. Collectively, they reduce the strain on the heart and improves heart functions.
Take AMDEPIN AT TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. AMDEPIN AT TABLET can be taken with or without meals.
Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Continue to take AMDEPIN AT TABLET for the stipulated duration instructed by your doctor to achieve better results.
Stop taking AMDEPIN AT TABLET and contact your doctor immediately if you experience any of the following side effects:
Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Take AMDEPIN AT TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.
AMDEPIN AT TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.
AMDEPIN AT TABLET should be used with caution in breastfeeding women as it may pass through the breast milk to the nursing infant. Therefore, consult your doctor before taking it.
Do not drive or operate any heavy tools or machines if you feel dizzy after taking AMDEPIN AT TABLET.
Avoid consumption of alcohol while taking AMDEPIN AT TABLET as it could make you feel dizzier.
AMDEPIN AT TABLET should be used with caution in patients with kidney problems (such as dialysis). Therefore, consult your doctor before taking it.
AMDEPIN AT TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.
Do not take AMDEPIN AT TABLET if you are allergic to Atenolol, Amlodipine or to any other beta blockers (such as propranolol) or calcium antagonists (such as nifedipine, diltiazem).
AMDEPIN AT TABLET should be used with caution in patients who have or previously had any breathing problems such as asthma. Therefore, consult your doctor before taking it.
AMDEPIN AT TABLET is not recommended for use in patients with severe heart problems such as heart failure, aortic stenosis (narrowing of arteries) or cardiogenic shock (inability of heart to pump blood). It should be used with caution in patients having a history of recent heart attack or heart failure. Therefore, consult your doctor before taking it.
AMDEPIN AT TABLET is not recommended for use in children and adolescents (aged below 18 years) due to lack of safety data. Therefore, consult your doctor for advice.
AMDEPIN AT TABLET should be used with caution in the elderly patients. Therefore, consult your doctor before taking it.
AMDEPIN AT TABLET is not recommended for use if you:
Before taking AMDEPIN AT TABLET, inform your doctor if you:
A. Drug-Drug interactions:
Before taking AMDEPIN AT TABLET, inform your doctor if you are taking any of the following medicines such as:
B. Drug-Food interaction:
Avoid drinking grapefruit juice while taking AMDEPIN AT TABLET, as it could lead to further decrease your blood pressure and may make you feel dizzier, drowsier or faint.
Overdosage:
If you or anyone else accidentally took more AMDEPIN AT TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include dizziness, fainting, light-headedness, weakness, shock, cool or clampy skin and shortness of breath.
| Drug | : | Amlodipine, Atenolol |
| Pharmacological Category | : | Calcium Channel Blocker, Beta blockers |
| Therapeutic Indication | : | Hypertension, Angina pectoris |
| Dosage Forms | : | Tablet, Capsule, Tabcap, Captab |
A: AMDEPIN AT TABLET is used to manage hypertension (also known as high blood pressure) and angina pectoris (chest pain caused by a lack of oxygen supply to the heart). It can also be used to reduce the risk of heart attack (myocardial infarction) among heart patients.
A: AMDEPIN AT TABLET is an antihypertensive medicine. Atenolol blocks the effects of certain hormones (adrenaline) in the body that naturally increase heart rate. This slows down the heartbeat and makes the heart pump blood with less force. Amlodipine is a vasodilator. It relaxes the blood vessels supplying the heart, which improves blood flow and oxygen supply to the heart muscles. Collectively, they reduce the strain on the heart and improve heart function.
A: Take AMDEPIN AT TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. AMDEPIN AT TABLET can be taken with or without meals. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition. Continue to take AMDEPIN AT TABLET for the stipulated duration instructed by your doctor to achieve better results.
A: If you have missed a dose of AMDEPIN AT TABLET, take it as soon as you remember. However, if it is time for the next dose of AMDEPIN AT TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of AMDEPIN AT TABLET to compensate for the missed ones.
A: Before taking AMDEPIN AT TABLET, inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have severe high or low blood pressure or other heart problems (such as narrowing of the arteries, cardiogenic shock, or a recent heart attack). Consult your doctor before taking AMDEPIN AT TABLET if you are pregnant and breastfeeding. Regularly visit your doctor and take all the necessary blood tests recommended by your doctor without fail.
A: Avoid consumption of alcohol while taking AMDEPIN AT TABLET, as it might make you feel dizzy.
A: If you or anyone else accidentally took more AMDEPIN AT TABLET, consult your doctor immediately. Symptoms of overdosage might include dizziness, fainting, light-headedness, weakness, shock, cool or clampy skin, and shortness of breath.
A: AMDEPIN AT TABLET may cause edema or swelling of the ankles in a few patients. If you experience ankle swelling, keep your legs on a table or slightly elevated from ground level. If this symptom bothers you, contact your doctor.
A: The most common side effects of taking AMDEPIN AT TABLET are swelling of ankles or other body parts, headache, dizziness, sleepiness, tiredness, racing heartbeat, indigestion, constipation, muscle cramps, cold hands and feet, and a slow heartbeat. Contact your doctor if any of these side effects trouble you.
A: No. Do not stop taking AMDEPIN AT TABLET without consulting your doctor. As hypertension is a chronic condition, long term treatment may be necessary to control its symptoms. Therefore, take AMDEPIN AT TABLET as advised by your doctor for the stipulated duration. Premature discontinuation of therapy may increase your blood pressure once again.
A: AMDEPIN AT TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.
A: AMDEPIN AT TABLET should be used with caution in breastfeeding women as it may pass through the breast milk to the nursing infant. Therefore, consult your doctor before taking it.
A: Before taking AMDEPIN AT TABLET, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, non-prescription, or any herbal medicine, as these might interact with each other and cause serious side effects.
A: Yes. AMDEPIN AT TABLET should be used with caution in patients with liver problems. Consult your doctor before taking it.
A: AMDEPIN AT TABLET may cause problems in erection in a few individuals. Consult your doctor if it bothers you.
A: AMDEPIN AT TABLET is not recommended for use in patients with severe heart problems such as heart failure, aortic stenosis (narrowing of arteries), or cardiogenic shock (inability of the heart to pump blood). It should be used with caution in patients with a history of recent heart attacks or heart failure. Therefore, consult your doctor before taking it.
1. KD. Tripathi. Antiadrenergic agents and drugs for glaucoma. Antianginal and Other Anti-ischaemic Drugs, Antihypertensive Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 149, 549 & 562-563.
2. Gerald G. Briggs and Roger K. Freeman. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 196-198 and 306-316.
3. Gang Ling, Ai-jun Liu, Fu-ming Shen, Guo-jun Cai, Jian-guo Liu & Ding-feng Su. Effects of combination therapy with atenolol and amlodipine on blood pressure control and stroke prevention in stroke-prone spontaneously hypertensive rats. Acta Pharmacologica Sinica. November 2007. [Accessed on 3rd January 2023] https://www.nature.com/articles/aps2007215
4. Kishen G. Bulsara; Manouchkathe Cassagnol. Amlodipine. StatPearls. NIH. National Library of Medicine, National Center for biotechnology information. PMC. PubMed Central. January 2022. [Accessed on 3rd January 2023] https://www.ncbi.nlm.nih.gov/books/NBK519508/
5. Dr. Reddy’s Laboratories (UK) Ltd. Electronic Medicines Compendium (EMC). [Revised in July 2022] [Accessed on 3rd January 2023] https://www.medicines.org.uk/emc/files/pil.3478.pdf
6. Zentiva Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 3rd January 2023] https://www.medicines.org.uk/emc/files/pil.13960.pdf
7. Accord Healthcare Limited, Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 3rd January 2023] https://www.medicines.org.uk/emc/files/pil.6025.pdf
8. Cipla Ltd. AMLOPRES AT Tablets (Amlodipine + Atenolol). Ciplamed. [Revised in December 2020]. [Accessed on 3rd January 2023] https://www.ciplamed.com/content/amlopres-at-tablets
9. Central Drugs Standard Control Organization. Amlodipine besylate eq. to Amlodipine 5mg+ Atenolol 50mg Besylate uncoated tablets. May 1996. [Accessed on 3rd January 2023] https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/dciApprovedfdc.pdf
10. Leeford Healthcare Pvt Ltd. Wellamo AT. [Accessed on 3rd January 2023] https://www.leeford.in/product/1150/wellamo-at
Written By Srilekha. R, B.Pharm
Last updated on 26 Feb 2024 | 12:19 PM(IST)