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INTRODUCTION LIGNOX 2% INJECTION contains Lignocaine, which belongs to the group of medicines called Local anaesthetic agents. It is used to cause numbness (loss of sensation) of body parts in the regions where it has been administered (local anesthesia). It is generally used prior to spinal a...
LIGNOX 2% INJECTION contains Lignocaine, which belongs to the group of medicines called Local anaesthetic agents. It is used to cause numbness (loss of sensation) of body parts in the regions where it has been administered (local anesthesia). It is generally used prior to spinal anesthesia or before surgical procedures to cause a temporary loss of sensation. It also helps to control the heartbeat in patients with arrythmia (an irregular heartbeat).
LIGNOX 2% INJECTION will be given to you only by a trained anaesthesiologist around the areas (such as hands, legs, abdomen, pelvis, and spine) locally where loss of sensation (numbness) is required.
Before receiving LIGNOX 2% INJECTION, inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you have any breathing disorders, blood problems, epilepsy, glaucoma, stroke, dehydration, low blood potassium levels, or muscle weakness.
LIGNOX 2% INJECTION should be used in pregnant or breastfeeding women only if considered necessary by the physician. The most common side effects of receiving LIGNOX 2% INJECTION are nausea, slow heart rate, dizziness, lower back pain, difficulty walking, and an inability to control urine or bowel movements. Inform your doctor if any of these side effects worsen.
LIGNOX 2% INJECTION is an anaesthetic agent. It reduces pain sensation and causes numbness in body parts by blocking the flow of certain ions (sodium ions) through the nerves that cause pain sensation. As a result, it limits the transfer of pain signals from the peripheral parts of the body (i.e., the face, hands, legs, abdomen, and pelvis) to the brain, which leads to a loss of sensation. It also normalizes heart rate by blocking the generation of abnormal electrical signals in the heart.
LIGNOX 2% INJECTION will be given to you only by a doctor or by a trained anaesthesiologist. Your doctor or anaesthesiologist will decide the correct dose and site of administration for you depending upon your age, body weight, health condition, and the type of nerve block that is required to provide anesthesia or pain relief.
It can be administered locally to the region where loss of sensation (numbness) is required or can be administered in a vein, around the spinal cord, or a nerve to cause numbness during surgeries (caesarean section or other major surgeries) to stop pain sensation.
Consult your doctor immediately if you experience any of the following side effects after receiving LIGNOX 2% INJECTION:
Avoid standing or walking after surgery. Try to rest and relax. Get enough sleep. Consult your doctor if you continue to feel dizzy for a prolonged period of time.
Place an ice pack on the injected site. Do not move the affected area frequently. If the symptom worsens, consult your doctor.
LIGNOX 2% INJECTION should be used in pregnant women only if it is considered necessary by the physician. Therefore, inform your doctor if you are pregnant or think you may be pregnant before receiving LIGNOX 2% INJECTION.
LIGNOX 2% INJECTION should be used for breastfeeding women only if it is considered necessary by the physician. Therefore, inform your doctor before receiving LIGNOX 2% INJECTION if you are breastfeeding.
LIGNOX 2% INJECTION may make you feel dizzy or drowsy for some time after administration. Therefore, do not drive or operate any heavy tools or machines if your abilities are affected by LIGNOX 2% INJECTION.
Avoid the consumption of alcohol before receiving LIGNOX 2% INJECTION.
LIGNOX 2% INJECTION should be used with caution in patients with kidney problems. Therefore, consult your doctor before receiving it.
LIGNOX 2% INJECTION should be used with caution in patients with liver problems. Therefore, consult your doctor before receiving it.
Inform your doctor before receiving LIGNOX 2% INJECTION if you are allergic to lignocaine or to any other local anaesthetics (such as bupivacaine).
LIGNOX 2% INJECTION should be used with caution in patients with breathing disorders (such as asthma or COPD). Therefore, consult your doctor before receiving it.
LIGNOX 2% INJECTION is not recommended for use in patients with heart diseases (such as heart block, an abnormal heartbeat, or a very slow heartbeat). It should be used with caution in patients with other heart disorders. Therefore, consult your doctor before receiving it.
LIGNOX 2% INJECTION should be used in children and adolescents (aged below 18 years) only if it is considered necessary by the physician. It is not recommended for use in neonates aged less than 1 month. Therefore, consult your doctor for advice before administration.
LIGNOX 2% INJECTION should be used with caution with elderly patients. Therefore, consult your doctor for advice before receiving it.
LIGNOX 2% INJECTION is not recommended for use if you:
Before receiving LIGNOX 2% INJECTION, inform your physician if you:
A. Drug-Drug interactions:
Before receiving LIGNOX 2% INJECTION, inform your doctor if you are receiving any of the following medicines:
Overdosage:
LIGNOX 2% INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms. Symptoms of overdosage might include lightheadedness, numbness of the tongue, or a ringing sound in the ears.
| Drug | : | Lignocaine |
| Pharmacological Category | : | Voltage Gated Sodium Channel Blockers |
| Therapeutic Indication | : | Local anesthesia, Arrythmia |
| Dosage Forms | : | Injection, Gel, Cream, Ointment, Jelly, Topical Solution, Spray, Oral solution, Plaster |
Q: How long will it take for LIGNOX 2% INJECTION to induce numbness?
A: It may take around 2–5 minutes for LIGNOX 2% INJECTION to create numbness in body parts. However, this period may vary from person-to-person based on the dose and amount of the LIGNOX 2% INJECTION that is administered to you.
Q: Is LIGNOX 2% INJECTION a narcotic medicine?
A: No. LIGNOX 2% INJECTION is not a narcotic. It is a local anaesthetic agent that is used to create a loss of sensation (numbness) in certain body parts following administration.
Q: Can LIGNOX 2% INJECTION affect blood pressure?
A: Yes. LIGNOX 2% INJECTION may cause changes in blood pressure (high or low blood pressure), so if you experience any unusual symptoms, like feeling extremely dizzy or lightheaded after receiving LIGNOX 2% INJECTION, consult your doctor.
Q: What are the common side effects of LIGNOX 2% INJECTION?
A: The most common side effects of receiving LIGNOX 2% INJECTION are nausea, slow heart rate, dizziness, lower back pain, difficulty walking, and an inability to control urine or bowel movements. Inform your doctor if any of these side effects worsen.
Q: What are the symptoms that could appear if I received an excessive amount of LIGNOX 2% INJECTION?
A: LIGNOX 2% INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms. Symptoms of overdosage might include light-headedness, numbness of the tongue, or a ringing sound in the ears.
Q: Can LIGNOX 2% INJECTION be used with children?
A: Yes. LIGNOX 2% INJECTION is used in children and in adolescents (aged between 18 years) only if it is considered necessary by the physician. It is not recommended for use in neonates aged below 1 month due to a lack of safety data.
Q: Can LIGNOX 2% INJECTION cause nerve damage?
A: Yes. LIGNOX 2% INJECTION may cause nerve damage when administered in excess. Therefore, inform your doctor if you experience signs of nerve damage (such as tingling in the hands and feet) while receiving LIGNOX 2% INJECTION.
Q: Is LIGNOX 2% INJECTION safe for use by pregnant women?
A: LIGNOX 2% INJECTION should be used in pregnant women only if it is considered necessary by the physician. Therefore, inform your doctor if you are pregnant or think you may be pregnant before receiving LIGNOX 2% INJECTION.
Q: How long do the effects of LIGNOX 2% INJECTION last in the body?
A: The effects of LIGNOX 2% INJECTION may last about 10–20 minutes after intravenous administration and for about 60–90 minutes after intramuscular administration. However, the recovery period may vary from person-to-person based on the dose and amount of the LIGNOX 2% INJECTION that is administered to you.
1. KD. Tripathi. Drugs acting on peripheral (somatic) nervous system. Essentials of medical pharmacology. 8th Edition. 2019. Page – 392.
2. Weinberg L, Peake B, Tan C and Nikfarjam M. Pharmacokinetics and pharmacodynamics of lignocaine: A review. World Journal of Anesthesiology. July 2015. [Accessed on 8th September 2022] https://www.wjgnet.com/2218-6182/full/v4/i2/17.htm
3. JOSE E. USUBIAGA, WILLIAM GUSTAFSON, FRANK MOYA AND BURTON GOLDSTEIN Departments of Anesthesiology and Psychiatry, University of Miami, School of Medicine and Jackson Memorial Hospital, Miami, Florida, US.A. The Effect of Intravenous Lignocaine on Cardiac Arrhythmias During Electroconvulsive Therapy. British Journal of Anesthesia. [Accessed on 8th September 2022] https://www.bjanaesthesia.org.uk/article/S0007-0912(17)51889-9/pdf
4. Mercury Pharmaceuticals Limited. Electronic Medicines Compendium (EMC). [Revised in May 2021] [Accessed on 8th September 2022] https://www.medicines.org.uk/emc/files/pil.4781.pdf
5. Hameln pharma ltd. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed on 8th September 2022] https://www.medicines.org.uk/emc/files/pil.6277.pdf
6. Mercury Pharmaceuticals (Ireland) Ltd. Electronic Medicines Compendium (EMC). [Revised in April 2016] [Accessed on 8th September 2022] https://www.hpra.ie/img/uploaded/swedocuments/2143491.PA0073_112_006.8f88df24-b092-4c3b-bf3f-294aa775a103.000001Lidocaine%20Hydrochloride%202%20PIL.170524.pdf
7. Innovative Pharmaceuticals Pvt Ltd. LIGNOCIN Injection 30ml. [Accessed on 8th September 2022] https://www.innovativepharma.in/product/lignocin-injection/
Written By Dr. N. Sai Swaroop, Pharm.D
Last updated on 02 Dec 2023 | 11:04 AM(IST)