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INTRODUCTION NIZONIDE 500MG TABLET contains Nitazoxanide which belongs to the group of medicines called Antiprotozoals. It is used to treat diarrhoea caused by Giardia lamblia or Cryptosporidium parvum. Diarrhoea occurs when not enough water is removed from the stool, or too much fluid is secr...
NIZONIDE 500MG TABLET contains Nitazoxanide which belongs to the group of medicines called Antiprotozoals. It is used to treat diarrhoea caused by Giardia lamblia or Cryptosporidium parvum. Diarrhoea occurs when not enough water is removed from the stool, or too much fluid is secreted into the stool, making it loose.
Avoid consumption of alcohol while taking this medicine. NIZONIDE 500MG TABLET is not effective for the treatment of diarrhoea caused by C. parvum in HIV-infected or immunodeficient patients. Before taking NIZONIDE 500MG TABLET, inform your doctor if you have kidney, liver, biliary problems.
NIZONIDE 500MG TABLET should be used with caution among pregnant women and breastfeeding women as safety data has not been established yet. NIZONIDE 500MG TABLET is not recommended for use in children under 11 years of age. It should be used with caution in elderly patients above 65 years of age. The most common side effects of taking NIZONIDE 500MG TABLET are abdominal pain, diarrhoea, headache, and nausea. Contact your doctor if any of the above symptoms worsen.
NIZONIDE 500MG TABLET works by disturbing the energy metabolism in anaerobic microbes. It changes the structure of protozoa cell membranes, mitochondrial membranes, and stops viral replication. Thus killing the protozoa and causing diarrhoea.
Take NIZONIDE 500MG TABLET as advised by your physician.
For Tablet, Capsule: Swallow NIZONIDE 500MG TABLET with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse NIZONIDE 500MG TABLET in the specified quantity of water as mentioned on the label. Consume the mixture immediately after reconstitution.
Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight and disease condition.
Headache:
Rest and relax. Keep yourself hydrated by drinking more fluids such as water or electrolytes. If needed apply a pain-relieving balm on the forehead. Avoid consumption of alcohol. If the symptoms do not improve, contact your physician for advice.
Nausea:
Stick to simple meals. Avoid eating oil-rich or spicy foods. If the symptoms do not improve, contact your physician for advice.
Diarrhoea:
Drink more fluids like water or fruit juice to keep yourself hydrated. Do not take any medicine on your own for diarrhoea without consulting your physician. If the symptoms do not improve, contact your physician for advice.
Stomach pain:
Rest and relax. Eat and drink slowly or try to have fewer and more frequent meals. Keep a heating pad on your stomach. If the symptoms do not improve, contact your physician for advice.
NIZONIDE 500MG TABLET should be used with caution in pregnant women or women planning to have a baby as safety data has not been established yet. Consult your doctor before taking it.
NIZONIDE 500MG TABLET should be used with caution in breastfeeding women as it is not known if it is excreted in breastmilk. Your doctor will weigh the potential benefits against the potential risks. Consult your doctor before taking it.
Avoid consumption of alcohol while taking NIZONIDE 500MG TABLET.
NIZONIDE 500MG TABLET should be used with caution in patients with kidney problems as safety data has not been established yet. Consult your doctor before taking it.
NIZONIDE 500MG TABLET should be taken with caution in patients with liver problems as safety data has not been established yet. Consult your doctor before taking it.
Do not take NIZONIDE 500MG TABLET if you are allergic to Nitazoxanide or any of the other ingredients of this medicine.
NIZONIDE 500MG TABLET is not recommended for use if you:
Before taking NIZONIDE 500MG TABLET inform your doctor if you:
Use in pediatrics:
NIZONIDE 500MG TABLET is not recommended for use in children under 11 years of age. Consult your doctor before taking it.
Use in geriatrics:
NIZONIDE 500MG TABLET should be used with caution in elderly patients (65 years and above). Consult your doctor before taking it.
A. Drug-Drug interactions:
Before taking NIZONIDE 500MG TABLET, inform your doctor if you are taking any of the following medicine:
Overdosage:
If you or anyone else accidentally took more of NIZONIDE 500MG TABLET, consult your doctor immediately or visit the nearby hospital.
| Drug | : | Nitazoxanide |
| Pharmacological Category | : | Antiprotozoals |
| Therapeutic Indication | : | Diarrhoea |
| Dosage Forms | : | Tablet, Oral Suspension, Suspension, Syrup, Dispersible |
What is NIZONIDE 500MG TABLET used for?
NIZONIDE 500MG TABLET is used to treat diarrhea caused by Giardia lamblia or Cryptosporidium parvum. Diarrhea occurs when not enough water is removed from the stool, or too much fluid is secreted into the stool, making it loose.
Can NIZONIDE 500MG TABLET cause headaches?
Yes. Headache is one of the most common side effects of taking NIZONIDE 500MG TABLET. In case your child is experiencing a headache after taking NIZONIDE 500MG TABLET, rest and relax. Keep hydrated by drinking more fluids such as water or electrolytes. If needed apply a pain-relieving balm on the forehead. Avoid consumption of a. If the symptoms do not improve, please consult your doctor.
What precaution is to be taken before taking NIZONIDE 500MG TABLET?
NIZONIDE 500MG TABLET should be used with caution in lactating and not recommended in children below 11 years of age. NIZONIDE 500MG TABLET should be used with caution in patients who have renal problems, hepatic problems, pregnant women, and elderly patients. Please consult your doctor before taking NIZONIDE 500MG TABLET.
Does NIZONIDE 500MG TABLET change urine colour?
Yes, NIZONIDE 500MG TABLET may change the colour of urine. This is normal and not harmful. if symptoms do not improve or get worse consult your doctor immediately.
How does NIZONIDE 500MG TABLET work?
NIZONIDE 500MG TABLET works by disturbing the energy metabolism in anaerobic microbes. It changes the structure of protozoa cell membranes, mitochondrial membranes, and stops viral replication. Thus killing the protozoa causing diarrhoea.
1. KD. Tripathi. Antiamoebic and Other Antiprotozoal Drugs. Drugs Essentials of medical pharmacology. Seventh edition. 2013. Page – 840-841.
2. Mohammad Rashidul Hashan, Khaled Mosaad Elhusseiny, Le Huu-Hoaiz, Thuan Minh Tieu , Soon Khai Low et.al. Effect of nitazoxanide on diarrhoea: A systematic review and network meta-analysis of randomized controlled trials. Journal of Acta Tropica. Science Direct. October 2020 [Accessed on 10th August 2022] https://www.sciencedirect.com/science/article/abs/pii/S0001706X19316328?via%3Dihub
3. Samarendra Mahapatro, Nijwm Mahilary, Amit Kumar Satapathy, and Rashmi Ranjan Das. Nitazoxanide in Acute Rotavirus Diarrhea: A Randomized Control Trial from a Developing Country. NIH. National Library of Medicine, National Center for Biotechnology information. Pubmed Central. February 2017 [Accessed on 10th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346365/
4. Romark Pharmaceuticals. US Food and Drug Administration. [Revised in June 2005] [Accessed on 10th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021818lbl.pdf
5. Romark Pharmaceuticals. ALINIA Tablets and Oral suspension. [Revised in April 2017] [Accessed on 10th August 2022] https://www.alinia.com/wp-content/uploads/2017/08/prescribing-information.pdf
6. Nitazoxanide. Mayoclinic. [Revised in November 2022] [Accessed on 10th August 2022] Nitazoxanide (Oral Route) Proper Use - Mayo Clinic
Written By Dr. Shruthi M R, BDS
Last updated on 13 Jan 2023 | 05:00 PM(IST)