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INTRODUCTION ADMENTA 5MG TABLET contains Memantine which belongs to the group of medicines called Anti-dementia drugs. It is used to treat moderate to severe Alzheimer’s disease. Alzheimer’s disease is a neurodegenerative disease that destroys memory and other important mental functions in an...
ADMENTA 5MG TABLET contains Memantine which belongs to the group of medicines called Anti-dementia drugs. It is used to treat moderate to severe Alzheimer’s disease. Alzheimer’s disease is a neurodegenerative disease that destroys memory and other important mental functions in an individual. It is caused due to formation and accumulation of certain toxic proteins in the brain that destroys brain cells. It can be characterized by loss of memory and forgetfulness of day-to-day activities.
Memantine is a N-methyl-D-aspartate (NMDA) receptor antagonist. It acts by blocking the over activation of certain chemicals (glutamate and beta-amyloid peptide) in the brain that causes Alzheimer’s disease. It can also block the activity of other chemical messengers (like serotonin and acetylcholine) which are responsible for affecting thoughts, memory and mental state.
Before taking ADMENTA 5MG TABLET, inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you have or have a family history of fits or if you made any sudden changes to your diet. During treatment with ADMENTA 5MG TABLET, your doctor would closely monitor your health condition to access the improvement and to avoid unwanted side effects.
ADMENTA 5MG TABLET should not be used in pregnant or breastfeeding women. It is also not suitable for use in children aged below 18 years. It should be used with caution in the elderly patients.
The most common side effects of taking ADMENTA 5MG TABLET are headache, dizziness, sleepiness and constipation. Consult your doctor if they trouble you. Also, inform your doctor if you unusually feel sad or depressed with suicidal thoughts after taking ADMENTA 5MG TABLET.
ADMENTA 5MG TABLET is a NMDA receptor antagonist. It acts by blocking the over activation of certain chemicals (glutamate and beta-amyloid peptide) within the brain that causes Alzheimer’s disease. It can also block the activity of other chemical messengers (like serotonin and acetylcholine) that affects thoughts, memory and mental state. As a result, it improves memory and stabilizes mental health.
Take ADMENTA 5MG TABLET as advised by your doctor. It can be taken with or without meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Try to take the medicine at the same time each day. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking ADMENTA 5MG TABLET without consulting your doctor.
Stop taking ADMENTA 5MG TABLET and contact your doctor immediately if you experience any of the following side effects:
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Consult your doctor if your dizziness worsens.
Constipation:
Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.
ADMENTA 5MG TABLET is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
ADMENTA 5MG TABLET is not recommended for use in breast feeding women. Therefore, consult your doctor before taking it.
Do not drive or operate heavy machines if your ability is affected by ADMENTA 5MG TABLET.
Avoid consumption of alcohol while taking ADMENTA 5MG TABLET as it might make you feel dizzy or drowsy.
ADMENTA 5MG TABLET should be used with caution in patients with kidney problems (such as renal tubulary acidosis, severe infections of the urinary tract or have problem in passing urine). Therefore, consult your doctor before taking it.
ADMENTA 5MG TABLET should be used with caution in patients with liver problems (such as jaundice or liver failure). Therefore, consult your doctor before taking it.
Do not take ADMENTA 5MG TABLET if you are allergic to Memantine.
ADMENTA 5MG TABLET should be used with caution in patients with heart problems (such as congestive heart failure, uncontrollable high blood pressure or a recent heart attack). Therefore, consult your doctor before taking it.
Before taking ADMENTA 5MG TABLET, inform your doctor if you have:
Use in pediatrics
ADMENTA 5MG TABLET is not recommended for use in children and adolescents (below 18 years). Therefore, consult your doctor before taking it.
Use in geriatrics
ADMENTA 5MG TABLET should be used with caution in elderly patients (65 years and above). Therefore, consult your doctor before taking it.
A. Drug-Drug interactions
Before taking ADMENTA 5MG TABLET, inform your doctor if you are taking any of the following medicines such as:
B. Drug - Food interactions
Consult your doctor if you have recently changed your diet (Ex. from normal diet to strict vegetarian diet) as there may be a need for dose adjustments.
Overdosage
If you or anyone else accidentally took more ADMENTA 5MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include feeling tired, slow heart rate, confusion, dizziness, increased blood pressure, feeling faint, psychosis, feeling agitated, restless or sleepy, slowed movement, unsteady movements, hallucinations, sensation of spinning and vomiting.
| Drug | : | Memantine |
| Pharmacological Category | : | N-methyl-D-aspartate (NMDA) receptor antagonist |
| Therapeutic Indication | : | Alzheimer’s disease |
| Dosage Forms | : | Tablet |
Is ADMENTA 5MG TABLET addictive in nature?
No. ADMENTA 5MG TABLET is not addictive in nature. However, consult your doctor if you experience any unusual withdrawal symptoms.
How and when ADMENTA 5MG TABLET should be taken?
Take ADMENTA 5MG TABLET as advised by your doctor. It can be taken with or without meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Try to take ADMENTA 5MG TABLET at the same time each day. Your doctor will decide the time of administration and number of doses per day depending upon your age, body weight and disease condition. Do not stop taking ADMENTA 5MG TABLET without consulting your doctor.
Can ADMENTA 5MG TABLET cure dementia?
ADMENTA 5MG TABLET can treat dementia which is caused due to Alzheimer’s disease. However, consult your doctor before taking it.
How long should I use ADMENTA 5MG TABLET to see the results?
Take ADMENTA 5MG TABLET until your doctor advises you to stop. Research shows that it may take around 6 months for ADMENTA 5MG TABLET to show results in the affected patients. However, this period may not be the same for everyone. It differs from patient-to-patient depending upon the severity of the disease. Therefore, consult your doctor for advice.
Can ADMENTA 5MG TABLET be used to enhance memory in children?
No. ADMENTA 5MG TABLET is not a memory enhancer. It only prevents the destruction of brain cells that carries memories in the aging people. It is not suitable for use in children and adolescents (under 18 years) to enhance memory.
Can I stop taking ADMENTA 5MG TABLET without consulting the doctor once I feel better?
Do not stop taking ADMENTA 5MG TABLET without consulting your doctor. There is no cure for Alzheimer’s disease. Medicines are available only to manage its symptoms, and so discontinuation of the therapy may make your symptoms to reappear once again. However, if you feel that your symptoms have disappeared, consult your doctor for advice. Your doctor will carefully evaluate your health condition before stopping the therapy.
Can ADMENTA 5MG TABLET make me feel sleepy?
Yes. ADMENTA 5MG TABLET may make you feel sleepy. If you feel sleepy, rest, and relax. Restrict yourself from doing activities that may put you in danger. Avoid driving or handling heavy tools or machines. Consult your doctor if this side effect bothers you.
What medicines should be avoided while taking ADMENTA 5MG TABLET?
Before taking ADMENTA 5MG TABLET it is important for you to inform your doctor about the use of other medicines that can make you feel more sleepy or drowsy such as ketamine, dextromethorphan, carbamazepine, or phenobarbital. You must also inform your doctor if you have any heart problems, mental disorders, stomach problems or muscle problems and taking medicines to treat the same (such as thioridazine, chlorpromazine, thiothixene, dantrolene, baclofen, cimetidine, ranitidine, quinidine, procainamide amiodarone, flecainide).
What happens when ADMENTA 5MG TABLET is taken along with hydrochlorothiazide?
Avoid taking ADMENTA 5MG TABLET with hydrochlorothiazide as it may reduce the effectiveness of ADMENTA 5MG TABLET. Inform your doctor if you are already taking hydrochlorothiazide before starting therapy with ADMENTA 5MG TABLET.
Can ADMENTA 5MG TABLET be taken along with donepezil?
Studies have shown better results in treatment of Alzheimer’s disease when ADMENTA 5MG TABLET is combined with donepezil. However, consult your doctor for advice.
Can ADMENTA 5MG TABLET be used in pregnant women?
ADMENTA 5MG TABLET is not recommended for use in pregnant women and in those who are planning to become pregnant. Therefore, consult your doctor before taking it.
Can ADMENTA 5MG TABLET cause headaches?
Yes. ADMENTA 5MG TABLET may cause headache in some individuals. In case of you are experiencing a headache after taking ADMENTA 5MG TABLET, try to rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on your forehead if needed. Do not consume too much of alcohol. Consult your doctor if your headache persists for a long time.
Can I use ADMENTA 5MG TABLET without consulting a doctor?
No. ADMENTA 5MG TABLET should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the disease. Do not take ADMENTA 5MG TABLET without consulting your doctor.
What can be done if I forget to take a dose of ADMENTA 5MG TABLET?
If you forget to take a dose of ADMENTA 5MG TABLET take it as soon as you remember. However, skip the missed dose if it is time for the next dose. Do not take a double dose to make up for a forgotten dose.
1. K.D Tripathi. CNS Stimulants and Cognition Enhancers. Essentials of Medical Pharmacology. Seventh edition. 2013. Page - 490.
2. Shinji Matsunaga, Taro Kishi, Ikuo Nomura, Kenji Sakuma, Makoto Okuya, Toshikazu Ikuta, Nakao Iwata. The efficacy and safety of memantine for the treatment of Alzheimer's disease. NIH: National Library of Medicine, National centre of biotechnology Information Pubmed.gov. October 2018. [Accessed on 21st May 2022] https://pubmed.ncbi.nlm.nih.gov/30222469/
3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in June 2021] [Accessed on 20th May 2022] https://www.medicines.org.uk/emc/files/pil.5295.pdf
4. Forest Pharmaceuticals, Inc. U.S. Food & Drug Administration. [Revised in October 2013] [Accessed on 20th May 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021487s010s012s014,021627s008lbl.pdf
Written By Srilekha. R, B.Pharm
Last updated on 29 Sep 2022 | 12:09 PM(IST)