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INTRODUCTION ACOLATE M TABLET is a combination of Levocetirizine and Montelukast which belongs to the group of medicines called H1 receptor antagonists and Leukotriene receptor antagonists respectively. ACOLATE M TABLET is indicated for the treatment and prevention of allergic rhinitis, chroni...
ACOLATE M TABLET is a combination of Levocetirizine and Montelukast which belongs to the group of medicines called H1 receptor antagonists and Leukotriene receptor antagonists respectively. ACOLATE M TABLET is indicated for the treatment and prevention of allergic rhinitis, chronic idiopathic urticaria (allergic skin reaction with red raised itchy bumps on skin) and bronchial asthma in adults and in adolescents (aged 15 years or above).
Allergic rhinitis (also known as hay fever) is a heterogeneous disorder characterized by inflammation of the inner lining of nose accompanied by nasal decongestion, repeated sneezing, wheezing, or a red, watery and itchy eyes.
It is usually caused by allergens such as pollens, dusts, mould or flakes of skin from certain animals and can occur seasonally or year-round. Bronchial asthma is a long-term medical condition in which the path of the airways becomes inflamed, narrow and swollen. Symptoms include coughing, wheezing and chest tightness.
ACOLATE M TABLET is contraindicated for use in patients having severe kidney impairment. Consult your doctor before use. Avoid consumption of alcohol while taking ACOLATE M TABLET as it could make you feel drowsier.
ACOLATE M TABLET may cause certain unpleasant neuropsychiatric events (such as anxiety, depression, nightmares, hallucinations or even suicidal thoughts) in some individuals. Contact your doctor immediately if you or anyone else experience such events during treatment with ACOLATE M TABLET.
The most common side effects of taking ACOLATE M TABLET are upper respiratory tract infection, fever, cough, inflammation of the pharynx, dryness of mouth, headache and sleepiness. Consult your doctor if any of the side effects worsen.
ACOLATE M TABLET provides relief from the symptoms of allergic rhinitis, asthma and urticaria where levocetirizine acts by blocking the actions of histamines (a substance that cause allergic reaction), at the H1 receptors present on the surface of cells and montelukast acts by blocking the action of leukotrienes D4 (an inflammatory molecule causing narrowing and swelling of the airways) in the lungs, thus causing relaxation of smooth muscle, reduction in swelling and/or inflammation of the airways and a marked decrease in the onset of allergic reactions.
Take ACOLATE M TABLET as advised by your physician. Swallow ACOLATE M TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of ACOLATE M TABLET for you depending upon your age, body weight and disease condition.
Stop giving ACOLATE M TABLET to your child and contact doctor immediately if your child experiences any of the following side effects:
Drink lots of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom did not improve.
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.
Try to take ACOLATE M TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom did not improve.
Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom did not improve.
ACOLATE M TABLET should be used with caution during pregnancy only if considered clearly necessary. Consult your doctor before taking ACOLATE M TABLET.
ACOLATE M TABLET should be used with caution in breast-feeding. Consult your doctor before taking ACOLATE M TABLET.
Do not drive or operate any machines if you experience sleepiness/drowsiness, fatigue or physical weakness. Consult your doctor before taking ACOLATE M TABLET.
Avoid consumption of alcohol while taking ACOLATE M TABLET as it could cause reduction in alertness and impairment of performance. Consult your doctor before taking ACOLATE M TABLET.
ACOLATE M TABLET is not recommended for use in patients with severe kidney impairment. It should be taken with extreme caution in patients with kidney disease. Consult your doctor before taking ACOLATE M TABLET.
ACOLATE M TABLET should be taken with caution in patients with liver disease. Consult your doctor before taking ACOLATE M TABLET.
Do not take ACOLATE M TABLET if you are allergic to Montelukast or Levocetirizine. Consult your doctor before taking ACOLATE M TABLET.
ACOLATE M TABLET is not recommended for use in patients with asthma attacks. Consult your doctor before taking ACOLATE M TABLET.
ACOLATE M TABLET is strictly not recommended for use in infants and children (aged below 15 years). Consult your child’s doctor for advice.
ACOLATE M TABLET should be used with caution in elderly patients (aged 65 years or above). Proper dose titrations and careful monitoring of kidney functions are required in such patients. Consult your doctor before taking ACOLATE M TABLET.
ACOLATE M TABLET is not recommended for use if you:
Before taking ACOLATE M TABLET, inform your physician if you:
A. Drug-Drug interactions:
Before taking ACOLATE M TABLET, inform your doctor, if you are taking any of the following medicines:
Overdosage:
If you or anyone else take too much of ACOLATE M TABLET, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms of ACOLATE M TABLET might include stomach pain, thirst, sleepiness, headache, vomiting, hyperactivity, agitation, excitation and restlessness.
| Drug | : | Levocetirizine, Montelukast |
| Pharmacological Category | : | H1 receptor antagonist, Leukotriene receptor antagonist |
| Therapeutic Indication | : | Allergic rhinitis, Bronchial asthma, Chronic idiopathic urticaria |
| Dosage Forms | : | Tablet, Capsule, Softgel capsule, Dispersible tablet, Syrup, Suspension |
Q: How long does it take for ACOLATE M TABLET to provide relief from symptoms?
A: Following oral administration with ACOLATE M TABLET, it is believed to provide relief from the symptoms of allergy and asthma within 30 minutes to an hour. Please note that the onset of action varies from product to product and consult your doctor if you have any queries.
Q: Can ACOLATE M TABLET be used to treat acute asthma attacks?
A: No, ACOLATE M TABLET is used only to prevent asthma attacks. ACOLATE M TABLET should not be used on an asthma attack that has been started already. Contact your doctor or go to the nearby hospital to avoid exacerbation of the attack.
Q: Can ACOLATE M TABLET be used in infants?
A: No, ACOLATE M TABLET is only meant to be used in adults and in adolescents (aged 15 years or above). ACOLATE M TABLET is strictly not recommended for use in children aged between 6 months to 11 years of age without consulting your doctor.
Q: Can ACOLATE M TABLET make you feel sleepy?
A: Yes, ACOLATE M TABLET may make you feel sleepy or drowsy. Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling sleepy. Avoid alcohol intake, as it could aggravate your existing condition. Consult your doctor if the symptom did not improve.
Q: Is ACOLATE M TABLET safe to use in patients with kidney problems?
A: ACOLATE M TABLET is not recommended for use in patients with severe kidney impairment. It should be taken with extreme caution in patients with kidney disease. Consult your doctor before taking ACOLATE M TABLET.
1. KD. Tripathi. Histamines and Antihistamines & Drugs for cough and bronchial asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 166-168 & 228-229.
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Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 24 Feb 2023 | 10:19 AM(IST)