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INTRODUCTION ABOUT TYFUSIN 500MG TABLET TYFUSIN 500MG TABLET contains Disulfiram which belongs to the group of medicines called Aldehyde Dehydrogenase Inhibitors. It is used to manage in patients with alcohol dependence (or alcohol addiction). It helps to manage...
TYFUSIN 500MG TABLET contains Disulfiram which belongs to the group of medicines called Aldehyde Dehydrogenase Inhibitors. It is used to manage in patients with alcohol dependence (or alcohol addiction). It helps to manage the habit of alcoholism in patients having a habit of drinking excessive alcohol (chronic alcoholism). TYFUSIN 500MG TABLET helps in reducing alcohol dependence. It creates aversion towards alcohol by creating various unpleasant symptoms (such as flushing, burning sensation, throbbing headache, increased sweating, chest tightness, dizziness, vomiting, visual disturbances and confusion).
Before taking TYFUSIN 500MG TABLET inform your doctor if you have any lung, liver, kidney or heart problems. You must also inform your doctor if you have diabetes, high or low blood pressure, thyroid problems, brain damage, fits or any mental disorders as a precaution. TYFUSIN 500MG TABLET should not be used in patients who have already consumed alcohol. It should be used only in patients who have not drunk alcohol for at least 24 hours prior to the first dose.
It is also not suitable for use in pregnant or breastfeeding women and in children (aged below 18 years). The most common side effects of taking TYFUSIN 500MG TABLET are drowsiness, tiredness, impotence, low sex drive, headache, sleepiness and metallic taste. Consult your doctor if any of these side effect worsens.
TYFUSIN 500MG TABLET helps in reducing alcohol dependence. It acts by blocking the actions of certain enzymes (such as aldehyde dehydrogenase) within the body that helps in breaking down a substance called acetaldehyde. As a result, it leads to the accumulation of an excessive amount of acetaldehyde in the body causing unpleasant physical reactions (such as flushing, burning sensation, throbbing headache, increased sweating, chest tightness, dizziness, vomiting, visual disturbances and confusion) that can create aversion towards alcohol which will eventually help in quitting alcoholism.
Take TYFUSIN 500MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Do not consume alcohol for at least 24 hours before taking the first dose of TYFUSIN 500MG TABLET. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight and disease condition.
Stop taking TYFUSIN 500MG TABLET and contact your doctor immediately if you experience any of the following side effects:
Try to rest and relax. Get enough sleep. Avoid driving or operating heavy tools or machinery while you feel drowsy. Avoid the consumption of alcohol as it could aggravate your drowsiness. Contact your doctor if the condition worsens.
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Try to take TYFUSIN 500MG TABLET with or just after meals. Stick to simple meals and avoid oily-rich or spicy foods. Consult your doctor if the nausea worsens.
TYFUSIN 500MG TABLET is generally not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it.
TYFUSIN 500MG TABLET is generally not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before taking it.
TYFUSIN 500MG TABLET may cause drowsiness and tiredness. Therefore, do not drive or operate any heavy tools or machinery if your ability is affected by [GBNEYWORD].
Avoid consumption of alcohol while taking TYFUSIN 500MG TABLET as it may lead to serious unwanted side effects.
TYFUSIN 500MG TABLET should be used with caution in patients with kidney diseases. Therefore, consult your doctor before taking it.
TYFUSIN 500MG TABLET should be used with caution in patients with liver diseases. Therefore, consult your doctor before taking it.
Do not take TYFUSIN 500MG TABLET if you are allergic to Disulfiram or any other ingredients of this medicine.
[GBNEYWORD] should be used with caution in patients with lung diseases such as asthma. Therefore, consult your doctor before taking it.
TYFUSIN 500MG TABLET is not recommended for use in patients with severe heart diseases (such as heart failure or coronary occlusion). Therefore, consult your doctor before taking it.
TYFUSIN 500MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
TYFUSIN 500MG TABLET should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.
TYFUSIN 500MG TABLET is not recommended for use if you:
Before taking TYFUSIN 500MG TABLET, inform your doctor if you:
A. Drug-Drug interactions:
Before taking TYFUSIN 500MG TABLET, inform your doctor if you are taking any of the following medicines such as:
Overdosage:
If you or anyone else accidentally took more of TYFUSIN 500MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include nausea, vomiting, stomach pain, diarrhoea, headache, drowsiness, fatigue, mental disorders, tiredness, rapid heartbeat, rapid breathing, high body temperature, low blood pressure, loss of muscle control and/or high blood sugar.
| Drug | : | Disulfiram |
| Pharmacological Category | : | Aldehyde Dehydrogenase Inhibitor |
| Therapeutic Indication | : | Chronic Alcoholism |
| Dosage Forms | : | Tablet |
A: It is used to manage in patients with alcohol dependence (or alcohol addiction). It helps to manage the habit of alcoholism in patients having a habit of drinking excessive alcohol (chronic alcoholism).
A: TYFUSIN 500MG TABLET acts by blocking the actions of certain enzymes (such as aldehyde dehydrogenase) within the body that helps in breaking down a substance called as acetaldehyde. This leads to the accumulation of an excessive amount of acetaldehyde in the body causing unpleasant physical reactions which will eventually help in quitting alcoholism.
A: TYFUSIN 500MG TABLET is considered safe at doses prescribed by the physician.
A: The most common side effects of taking TYFUSIN 500MG TABLET are drowsiness, tiredness, impotence, low sex drive, headache, sleepiness and metallic taste. Consult your doctor if any of these side effects worsen.
A: No. Take TYFUSIN 500MG TABLET every day until your doctor tells you to stop. Do not stop taking this medicine abruptly or reduce the dose without consulting your doctor. Your doctor will assess your disease condition regularly and will increase or decrease the dose accordingly.
A: Always consume the dose prescribed for you by your physician. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight and severity of the disease. Do not take a higher dose of this medicine without consulting your doctor as it could lead to unwanted side effects. If your symptoms are not relieved by the prescribed dose, consult your doctor so that he might adjust the dose according to your health condition or can suggest an alternative therapy.
A: TYFUSIN 500MG TABLET is generally not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it.
A: TYFUSIN 500MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
A: If you forget to take TYFUSIN 500MG TABLET, take it as soon as you remember. However, if it's time for the next dose, skip the missed dose and take the next dose. Do not take a double dose to compensate for the missed dose.
A: Take TYFUSIN 500MG TABLET as advised by your physician. Your doctor will evaluate your health condition and suggest whether can you take TYFUSIN 500MG TABLET every day or not.
1. KD. Tripathi. Ethyl and Methyl alcohol. Drugs acting on CNS. Essentials of medical pharmacology. Seventh edition. 2013. Page – 394.
2. Maranda Stokes; Sara Abdijadid. Disulfiram. StatPearls [Internet]. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. [Revised in November 2021]. [Accessed on 2nd December 2022] https://www.ncbi.nlm.nih.gov/books/NBK459340/
3. Marilyn D. Skinner, Pierre Lahmek, Héloïse Pham and Henri-Jean Aubin. Disulfiram Efficacy in the Treatment of Alcohol Dependence: A Meta-Analysis. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. February 2014. [Accessed on 2nd December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919718/
4. Brown & Burk UK Ltd. Electronic Medicines Compendium (EMC). [Revised in June 2021] [Accessed on 2nd December 2022] https://www.medicines.org.uk/emc/files/pil.11168.pdf
5. Leeford Healthcare Pvt Ltd. Recopress 500. [Accessed on 2nd December 2022] https://www.leeford.in/product/791/recopress-500
Written By Dr. Janet.C, Pharm.D
Last updated on 17 Feb 2024 | 12:45 PM(IST)