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INTRODUCTION ACNESOL GEL contains Clindamycin, which belongs to the group of medicines called Antibiotics. It is used in the treatment of acne vulgaris. Acne vulgaris is a common skin condition that occurs when hair follicles get blocked with oil and dead skin cells. Symptoms include whitehead...
ACNESOL GEL contains Clindamycin, which belongs to the group of medicines called Antibiotics. It is used in the treatment of acne vulgaris. Acne vulgaris is a common skin condition that occurs when hair follicles get blocked with oil and dead skin cells. Symptoms include whiteheads, blackheads, small red, tender bumps, pimples, and pus-filled lumps on the skin.
Before applying ACNESOL GEL, inform your doctor if you have or ever had diarrhea, bloody diarrhea and pseudomembranous colitis. ACNESOL GEL is not recommended for use if you have a history of regional enteritis (inflammation of the small intestine), ulcerative colitis (inflammation of the large intestine) or antibiotic-associated colitis.
ACNESOL GEL should be used with caution during pregnancy or by breastfeeding women only if clearly needed. The safety and effectiveness of ACNESOL GEL in children under the age of 12 has not been established. The most common side effects of applying ACNESOL GEL are burning, itching, and redness of the skin. Consult your doctor if symptoms worsen.
ACNESOL GEL acts against the bacteria by binding to the 50S subunit of the bacterial ribosome (site of protein synthesis), which in turn prevents protein synthesis and kills the infection-causing bacteria.
Apply ACNESOL GEL as advised by your physician. It is for external use only. Wash your hands before use. Wash and dry the whole area, apply a thin film once daily to the skin where acne lesions appear and use enough to cover the entire affected area. In case of contact with the eyes, mouth or nostrils, rinse it off immediately and thoroughly with water. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
Stop applying ACNESOL GEL and contact your doctor immediately if you experience any of the following side effects:
The safety and effectiveness of ACNESOL GEL in pregnant women or women planning to have a baby have not been established yet. It will be given to you by the doctor only if clearly needed. Consult your doctor before applying ACNESOL GEL.
ACNESOL GEL should be used with caution in breastfeeding women as it is not known if the medicine is excreted in human milk. Your doctor will decide whether to discontinue nursing or the medicine, considering the benefits to the mother and baby. If it is applied to the chest, care should be taken to avoid accidental ingestion by the infant. Consult your doctor before applying ACNESOL GEL.
Do not apply ACNESOL GEL if you are allergic to Clindamycin or any other ingredients of this medicine.
ACNESOL GEL is not recommended for use if you:
Before applying ACNESOL GEL inform your doctor if you:
Use in pediatrics:
Safety and effectiveness of ACNESOL GEL in children under the age of 12 have not been established. Consult your doctor before applying ACNESOL GEL.
A. Drug-Drug interactions:
Before applying ACNESOL GEL, inform your doctor if you are taking any of the following medicine:
Overdosage:
If you or anyone else accidentally applied too much of ACNESOL GEL, consult your doctor immediately or visit the nearby hospital.
| Drug | : |
Clindamycin |
| Pharmacological Category | : |
Lincosamides |
| Therapeutic Indication | : |
Acne vulgaris |
| Dosage Forms | : |
Injection, Tablet, Capsule, Gel, Cream, Lotion, Solution, Spray, Soap |
What is ACNESOL GEL used for?
ACNESOL GEL is used in the treatment of acne vulgaris. Acne vulgaris is a common skin condition that occurs when hair follicles get blocked with oil and dead skin cells. Symptoms include whiteheads, blackheads, small red, tender bumps, pimples, and pus-filled lumps on the skin.
How to use ACNESOL GEL?
Apply ACNESOL GEL as advised by your physician. It is for external use only. Wash your hands before use. Wash and dry the whole area, apply a thin film once daily to the skin where acne lesions appear and use enough to cover the entire affected area. In case of contact with the eyes, mouth or nostrils, rinse it off immediately with plenty of water.
How does ACNESOL GEL work?
ACNESOL GEL acts against the bacteria by binding to the 50S subunit of the bacterial ribosome (site of protein synthesis), which in turn prevents protein synthesis and kills the infection-causing bacteria.
Can ACNESOL GEL be used in pregnancy?
The safety and effectiveness of ACNESOL GEL in pregnant women or women planning to have a baby have not been established yet. It will be given to you by the doctor only if clearly needed. Consult your doctor before applying ACNESOL GEL.
Can ACNESOL GEL be used in breastfeeding women?
ACNESOL GEL should be used with caution in breastfeeding women as it is not known if the medicine is excreted in human milk. Your doctor will decide whether to discontinue nursing or the medicine, considering the benefits to the mother and baby. If it is applied to the chest, care should be taken to avoid accidental ingestion by the infant. Consult your doctor before applying ACNESOL GEL.
1. KD Tripathi. Macrolide, Lincosamide, Glycopeptide and Other Anti bacteria IN Antibiotics. Urinary Antiseptics. Essentials of Medical Pharmacology. Eighth Edition. 2019. Page –805-806.
2. Patrick B, Murphy, Karlyle G. Bistas, Jacqueline K.Le. Clindamycin. National Library of medicine, National center for biotechnology information. [Revised in July 2021] [Accessed on 11th May 2022] https://www.ncbi.nlm.nih.gov/books/NBK519574/
3. Manuel Polanco Morales, Anna Paola Thome Carvallo, Karla Adriana Bautista Espinosa,and Edgar Enrique Meza Murillo. A young man with myelosuppression caused by clindamycin: a case report. National Library of medicine, National center for biotechnology information. Pubmed Central 2014. [Accessed on 11th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917410/
4. DPT Laboratories, Ltd.U.S. Food & Drug Administration. (Clindamycin topical gel). [Revised in November 2000] [Accessed on 11th May 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2001/50782lbl.pdf
5. Perrigo Yeruham. Daily med. (Clindamycin phosphate lotion). [Revised in December 2021] [Accessed on 11th May 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=a10dda0c-28fa-4678-8cea-a6ce2fce4b52
6. Pharmaceutical Society of Singapore. Clindamycin gel/solution/lotion 1%. [Revised in March 2016] [Accessed on 11th May 2022] https://www.pss.org.sg/sites/default/files/public-resource/clindamycin_pil_31-3-2016.pdf
7. Taro Pharmaceutical Industries Ltd. Dailymed. (Clindamycin topical solution). [Revised in April 2021] [Accessed on 11th May 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=5b8a6767-2d46-401c-9f85-d427dda9eff7
8. Torque Pharma. Ticin Gel. (Clindamycin gel 1%). [Accessed on 11th May 2022] https://www.torquepharma.com/ticin-gel/
Written By Dr. Dhivakaran R, BDS
Last updated on 26 Oct 2022 | 04:32 PM(IST)