INTRODUCTION

ACNELAK CLZ CREAM is a combination of Clindamycin and Zinc acetate which belongs to a group of medicines known as Antibiotics and Minerals respectively. It is used to treat mild to moderate acne.

Acne is a long-term skin condition that occurs when hair follicles plug with oil and dead skin cells which may be triggered by bacteria. It is characterised by uninflamed blackheads to pus-filled pimples or large, red and tender bumps.

Before using ACNELAK CLZ CREAM inform your doctor if you have inflammatory bowel disease (Ex. colitis or Crohn’s disease). Consult your doctor for advice.

ACNELAK CLZ CREAM should be used with caution in pregnant and breastfeeding woman as it may excrete in breastmilk and may pass to the baby. Consult your doctor for advice.

ACNELAK CLZ CREAM is not recommended for use in children and adolescents below 12 years of age. Consult with your physician.

The common side effects are skin dryness, skin burning sensation, redness of skin, worsening of acne, itchiness, irritation around the eyes. Consult your doctor if any of the side effects worsens.

USES OF ACNELAK CLZ CREAM

• Used to treat mild to moderate acne

HOW ACNELAK CLZ CREAM WORKS

ACNELAK CLZ CREAM works effectively where Clindamycin acts by inhibiting the protein synthesis which is necessary for the bacterial growth thereby it stops the growth of acne causing bacteria. Zinc acetate reduces the sebum production, inhibits the neutrophils and TNF production (substances responsible for inflammation), increases the tissue healing capacity and it also supress the bacterial growth.

DIRECTIONS FOR USE

Use ACNELAK CLZ CREAM as directed by your physician. It is for external use only. Wash as usual and pat dry the skin. A thin film of ACNELAK CLZ CREAM should be applied in affected area only.

SIDE EFFECTS OF ACNELAK CLZ CREAM

WARNING & PRECAUTIONS

PREGNANCY

ACNELAK CLZ CREAM should be used with caution in pregnant woman or if you think you might be pregnant. Consult your doctor for advice.

BREASTFEEDING

ACNELAK CLZ CREAM should be used with caution in breastfeeding woman as it is excreted in breastmilk and may pass to the baby. Consult your doctor for advice.

ALLERGY

Do not use ACNELAK CLZ CREAM if you are allergic to Clindamycin and Zinc acetate or any other ingredients of this medicine.

INTERACTIONS

A. Drug - Drug interactions:

Before using ACNELAK CLZ CREAM, inform your doctor if you are taking any of the following medicine:

• erythromycin, metronidazole, gentamicin, neomycin (medicines used to treat infections)

Overdosage:

If you or anyone else accidentally applies too much of ACNELAK CLZ CREAM, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep ACNELAK CLZ CREAM out of reach of children
• Store at a temperature below 25°C

FAQs ABOUT ACNELAK CLZ CREAM

Q: What is ACNELAK CLZ CREAM used for?

A: ACNELAK CLZ CREAM is a combination of Clindamycin and Zinc acetate. It is used to treat mild to moderate acne characterised by uninflamed blackheads to pus-filled pimples or large, red and tender bumps.

Q: How to use ACNELAK CLZ CREAM?

A: Always use ACNELAK CLZ CREAM as directed by your physician. Wash as usual and pat dry the skin. A thin film of ACNELAK CLZ CREAM should be applied in affected area only. It is for external use only.

Q: Is ACNELAK CLZ CREAM safe in pregnant and breastfeeding women?

A: ACNELAK CLZ CREAM should be used with caution in pregnant and breastfeeding woman as it may excrete in breastmilk and may pass to the baby, consult your doctor for advice.

Q: Is ACNELAK CLZ CREAM safe for use in children?

A: ACNELAK CLZ CREAM is not recommended for use in children and adoelscents below 12 years of age. Consult your doctor for advice before taking ACNELAK CLZ CREAM.

Q: Does ACNELAK CLZ CREAM cause burning sensation?

A: Yes, it may cause burning sensation in some individuals. Try to avoid hot showers because it may cause skin irritation. Avoid frequent contact and rubbing over the affected area. Use sunscreen and protective clothing when outdoors. If this symptom does not get better, speak to a doctor.

REFERENCES

1. KD. Tripathi. Macrolide, Lincosamide, Glycopeptide and Other Anti bacteria I Antibiotics; Urinary Antiseptics. Essentials of medical pharmacology. Eighth edition. 2019. Page – 805.

2. Capitanio B., Sinagra J. L. Role of clindamycin and zinc acetate in topic acne therapy. Edizioni Minerva Medica. March 2012. [Accessed 11th August 2022] https://www.minervamedica.it/en/journals/esperienze-dermatologiche/article.php?cod=R50Y2012N01A0021&acquista=1

3. Mrinal Gupta, Vikram K. Mahajan, Karaninder S. Mehta and Pushpinder S. Chauhan. Zinc Therapy in Dermatology: A Review. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. July 2014. [Accessed 11th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120804/

4. Clindamycin. NIH National Library of Medicine, National centre for biotechnology information. PubChem. August 2022. [Accessed 11th August 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Clindamycin

5. Patrick B. Murphy; Karlyle G. Bistas; Jacqueline K. Le. Clindamycin. NIH National Library of Medicine, National center for biotechnology information. StatPearls. May 2022. [Accessed 11th August 2022] https://www.ncbi.nlm.nih.gov/books/NBK519574/

6. Dr. August Wolff GmbH & Co. Health Products Regulatory Authority (HPRA). Revised in January 2021. [Accessed 11th August 2022] https://www.hpra.ie/img/uploaded/swedocuments/8e822675-a0ec-424a-89e2-d5813f57203a.pdf

USEFUL DIAGNOSTIC TESTS

• Complete blood count

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 04 Jan 2023 | 05:46 PM(IST)